Global ETD Search

1	Study and comparison of next generation sequence algorithms and tools Yates, Heath Landon January 1900 (has links) Master of Science / Department of Computing and Information Sciences / Doina Caragea / This study is a comparison and exploration of next generation sequencing algorithms and tools. A simulation study was done to compare the performance of edgeR, DESeq, and baySeq in detecting differential gene expression. The methods were compared in context of a balanced pairwise design. The simulation results suggest that the methods are compa- rable under the conditions simulated. The study also explored real data comprised of one biological replicate between two treatments. Cufflinks and CummerRBund were used to detect differential gene expression. The visualization results from the real data suggest no differential expression is present. NGS BaySeq EdgeR DESeq Cufflinks Computer Science (0984)
2	Improved tag-count approaches for label-free quantitation of proteome differences in bottom-up proteomic experiments Branson, Owen E. January 2016 (has links) No description available. Biochemistry Proteomics Shotgun Proteomics label-free spectral counting spectral count edgeR DESeq baySeq MultiSpec