The subject of this thesis is the design and project documentation of a new multifunctional house in Strakonice. The building has four floors, without basement, and is located on a slightly sloping land in the suburban part of the town of Strakonice. It is based on shallow foundations and covered with a flat roof. It is a transverse wall structural system, build with clay block masonry, with the semi-assembled ceiling structures of ceramic and concrete beams and inserts. It is conceived as a double-aisle layout. The ground floor of each wing consists of the establishment of shops and house facilities. The overground floors are designed as six residential units of varying size category. Both tracts have separate entrances to both the residential portion and to individual businesses. The building is designed from traditional building materials. In addition to the architectural construction and civil-engineering design, a part of this project is also a fire safety design and an assessment from the perspective of building physics.