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Génomique des populations appliquée : détection de signatures de sélection au sein de populations expérimentales / Applied population genomics : detection of signatures of selection in experimental populationsHubert, Jean-Noël 21 June 2018 (has links)
La génomique des populations rend possible la mise en évidence de traces de sélection dans le génome. Les travaux effectués considèrent en général une échelle de temps longue (~ 10³ générations). En comparaison, peu d’intérêt a été porté aux études expérimentales de court terme (~ 10 générations). De telles expériences sont pourtant susceptibles de nous renseigner sur la base génétique de caractères complexes. Nous proposons une méthode de vraisemblance basée sur un modèle de Wright-Fisher pour détecter la sélection à partir d’échantillons génétiques temporels acquis sur une période de dix générations. Nous montrons par simulation que notre méthode permet de différencier les signaux dus à la combinaison de la sélection et de la dérive génétique de ceux dus à la dérive seule. Nous montrons également par simulation qu’il est possible d’estimer le coefficient de sélection appliqué à un locus testé. De plus, nous illustrons l’intérêt de notre méthode pour la détection de marqueurs candidats à la sélection au travers de deux études génomiques sur données réelles, chez le diable de Tasmanie (Sarcophilus harrisii) et chez la truite arc-en-ciel (Oncorhynchus mykiss). Ces applications mettent en évidence des régions génomiques candidates pour des phénotypes complexes dans des contextes différents. Dans l’ensemble, nos résultats montrent qu’il est possible de détecter des gènes sujets à une sélection directionnelle intense à partir d’échantillons génétiques temporels, même si la sélection est de courte durée et si les populations examinées ont un faible effectif. / Population genomics makes it possible to detect traces of selection in the genome. Studies in this field have mainly focused on long time scale (~ 10³ generations). In comparison, short-term experimental studies (~ 10 generations) have attracted much less interest. Such experiments are, however, likely to inform us about the genetic basis of complex characters. We propose a likelihood method based on a Wright-Fisher model to detect selection from genetic temporal samples collected over ten generations. We show through simulation that our method can disentangle signals due to the combination of genetic drift and selection to those due to drift alone. We also show through simulation that it is possible to estimate the selection coefficient applied to a tested locus. In addition, we illustrate the interest of our method for the detection of candidate markers for selection through two genome scans performed on real data, in the Tasmanian devil (Sarcophilus harrisii) and in the rainbow trout (Oncorhynchus mykiss). These practical applications highlight candidate genomic regions for complex phenotypes in different contexts. Collectively, our results show the possibility of detecting genes submitted to strong directional selection from genetic time-series, even if selection is applied on a short time period and if the examined populations are small.
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Revolutionary Satan: A Reevaluation of the Devil's Place in Paradise LostLavelle, William H. 30 April 2015 (has links)
No description available.
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Female Friendship Films: A Post-Feminist Examination of Representations of Women in the Fashion IndustryGeloğullari, Gülin 12 1900 (has links)
This thesis focuses on three fashion industry themed female friendship films: Pret-a-Porter/Ready to Wear (1994) by Robert Altman, The Devil Wears Prada (2006) by David Frankel, and The September Issue (2009) by R.J. Cutler. Female interpersonal relationships are complex – women often work to motivate, encourage and transform one another but can just as easily use tactics like intimidation, manipulation, and exploitation in order to save their own jobs and reputations. Through the lens of post-feminist theory, this thesis examines significant female interpersonal relationships in each film to illustrate how femininity is constructed and driven by consumer culture in the fashion industry themed films.
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Investigating the prevalence of Satanism in Zambia with particular reference to the Kabwe districtKayuni, Hachintu Joseph 04 1900 (has links)
This study examined the alleged prevalence of Satanism in Zambia, with a particular reference to the Kabwe District during the period 2010-2013. The overall objective was to ascertain the claims and speculations on the alleged prevalence of Satanism in the district of Kabwe.
The claims about the alleged prevalence of Satanism and the satanic scare were found by this study to be a reality in Kabwe, with eighty-eight per cent (88%) of the respondents acknowledging the alleged prevalence of the phenomenon. People’s knowledge of Satanism was mainly through rumours, messages from Churches and the electronic media. Studies on rumours (by Stephen Ellis, Gerrie Ter Haar and Jeffrey Victor) have shown that rumours can be investigated in the search for facts, especially rumours that offer plausible explanations for people’s shared anxieties. The above mentioned scholars argue that with efforts at corroboration, such as by interviewing key informants, the researcher can seek credibility on prevailing rumours by verifying or dismissing mere rumours from true stories.
The assertions from scholars above justified the use of rumours as a methodological tool in this study. From sources of information the study relied on, claims about the alleged prevalence of Satanism in the district were investigated. The study refuted the satanic claims in a number of cases that were analysed, because they were mostly based on ‘pious legends’ hence lacked objective evidence. From the few incidents that suggested the prevalence of Satanism, there were still two basic problems faced in assessing their credibility: the first being the difficulty in determining the reliability of the confessions from informants who in this case either claimed they were ex-Satanists or served on behalf of Satanists. The second problem consisted in what seemed to be the inconsistency in the explanations of motives behind human killings found in the ritual murders. Some explanations did not suggest satanic motives.
One example of refuted claims concerned the two locations within Kabwe district which were highly rumoured to be sites for Satanists, which were found by this study to be Freemasonry Lodges, contrary to what was rumoured.From the findings of this study, it was believed that people joined Satanism either because of the greedy for riches or to avoid poverty. It was also believed that other peoples joined Satanism unconsciously through luring methods used by Satanists.
The study also found the satanic scare to have effects on the lives of people in the district. For example, it caused some people to become more committed Christians in their defence against the alleged satanic forces. Because people had associated riches to Satanism, certain individuals avoided getting rich for fear of being labelled ‘Satanists’. / Religious Studies & Arabic / D. Litt. et Phil. (Religious Studies)
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Sounds of satire, echoes of madness : performance and evaluation in Cefalonia, GreecePollatou, Efpraxia January 2009 (has links)
This thesis is about the construction of 'satire' as an exclusive practice among the Cefalonian and hence proposes the term satiricity (satirikotita). It explores the construction of the category of the Cefalonian "madman" by means of dialogics between performance and evaluation. It is observed that the relation depends on three principles that obtain among audience members and a performer: conditioning the performance, participation in and observation of the performance and evaluation of it. Being one of the few anthropological studies on the Ionian islands of Greece, this thesis aims to contribute to the anthropology of the Ionian islands and of Cefalonia in particular. It looks at the relation between a town and a village on the ground of teasing events and refutes the argument of satire as an urban phenomenon only. It sets the elementary principles towards anthropology of satire and emphasizes the importance of studying everyday teasing events. It also contributes to understanding a 'native' researcher's presence in different ways. Satiricity is seen as a 'par excellence' feature that Cefalonians have. No matter if Cefalonia is a part of the Greek nation-state and people follow 'modern Greek culture', they still employ satiricity as a way of distancing themselves from Greeks. 'Distance' is forged on the basis of absolute exclusion of Greeks from having, practising and understanding satiricity in the way that Cefalonians do. The Conclusions leave the ground open for more investigation on teasing events and application of such viewpoints around other areas of the island, and of the Ionian islands or other Greek islands. I also point to studies looking at island and mainland teasing events and potential differences. After all, we need to examine not only how people construct the claim on the exclusivity of 'satire'. We need to examine how such a claim is applied, supported or contrasted and possibly rejected when Cefalonians engage with other Greeks away from the island.
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Penser le mal moral, une généalogie de la volonté moderne / Thought about evil a genealogy of modern willTauty, Anne-Charlotte 20 September 2016 (has links)
Le mal est par sa nature un scandale car il se définit par ce qui ne devrait pas être à l’opposé du bien qui se présente comme ce qui doit être. Cette affirmation, qui relève de la tautologie, marque la réalité éprouvée face au mal. Il a d’abord été une évidence criante : comment réagir face aux maux de l’existence humaine ? Ainsi le mal est inscrit dans l’histoire de la pensée et commence pour notre travail avec le platonisme. Avant la conceptualisation platonicienne, le mal est une donnée factuelle de la vie avec laquelle il faut composer. Les figures divines sont ambivalentes à l’image des hommes et alternent vices et vertus. Platon postule une entité divine unique, omnisciente, omnipotente et bienveillante. Ce dieu devient intelligence, calcul et raison : le monde devient une création parfaite, belle et ordonnée et non plus le théâtre d’un affrontement entre les diverses passions des dieux. Le mal se transforme alors en un enjeu métaphysique : comment concilier cette perfection avec l’émergence du mal ? Il faut désormais expliquer et tenter de justifier la violence et les crimes. S’il est possible de proposer une théodicée qui rende le mal physique et métaphysique nécessaire, légitimer la méchanceté se révèle plus ardu. Les penseurs du platonisme, du néoplatonisme et du stoïcisme vont tenter d’apporter une première réponse au mal moral. Dans leur sillage, une rupture conceptuelle advient et révolutionne le concept : le christianisme invente le péché. En devenant péché, le mal se retrouve désormais sous la responsabilité de l’homme coupable. Le mal entre dans le giron de la liberté : il est voulu, consenti. A la suite des penseurs chrétiens, certains philosophes continueront ce travail d’élucidation de la volonté du mal. L’objectif est de retracer l’histoire de ces systèmes conceptuels qui s’entremêlent et se répondent les uns aux autres. Le mal moral se construit dans cette progression qui a des conséquences anthropologiques importantes : l’homme se pense à travers le mal. La méchanceté n’est donc pas seulement un problème à résoudre, elle devient le paradigme à travers lequel définir l’homme. Notre problématique est de montrer comment la question de la méchanceté est à la base du problème de la morale et comment elle conditionne notre représentation de la nature de la volonté humaine. Cette évolution s’est nouée lors d’étapes clés de la pensée philosophique. En effet, si dans toute philosophie morale, le concept du mal est évoqué, il n’est pas en général le centre de l’argumentaire. Le premier moment est celui de la pensée antique. Platon fait naître Dieu et le monde dans l’histoire des concepts puis se retrouve face l’énigme de nos crimes. La théodicée mise en place et qui sera reprise par Plotin et les Stoïciens ne cessera de nier l’existence d’un instinct pervers. Le mal voulu est une absurdité. L’irruption de la faute chrétienne bouleverse la donne. Saint Augustin en sera le théoricien le plus investi affectivement. Ayant expérimenté une double conversion dans sa vie spirituelle, il théorise une méchanceté issue de notre faiblesse, de notre faute première. Le mal est voulu car il n’est plus possible de vouloir autre chose. Saint Anselme reprend également le dogme de la chute mais lui apporte une dimension logique et sémantique en proposant une méchanceté égoïste. Le mal est certes voulu mais par dédain du bien. Notre dernière étape est kantienne. Le mal radical est le concept qui permet enfin de penser une volonté normale qui voudrait le mal simplement parce qu’elle a en elle cette possibilité et la liberté fondamentale de le choisir. Nous pourrons donc constater le chemin parcouru entre notre point de départ et notre point d’arrivée et comment cette problématisation du mal fait apparaître une généalogie de la volonté. Au fil de la pensée, elle passe de l’ombre à la lumière, n’étant jamais aussi présente que quand elle se retrouve confrontée aux obstacles. Penser le mal moral c’est faire l’archéologie de la volonté. / Evil provokes scandal by nature because it is what it should not be unlike good which is what it has to be. This tautological assertion expresses our feelings toward evil. It was first perfectly obvious : how must we face human pain ? Evil is a part of thinking’s history : our study starts with Platonism. Before his work, evil is just a fact of life you have to live with. The gods of Antiquity are like men : good or bad. The God of Plato is the one, omniscient, all-powerful and kindly. God is just intelligence, calculation and reason : the world he created is beautiful, ordered and perfect and it is no longer the place for the vices of ancient gods. Evils turns into a metaphysical issue : how can be the world perfect despite evil ? We have now to explain, to justify violence and crimes. Theodicy can justify pain and illness. It does not work with wickedness. Platonism, Neo-Platonism and Stoicism tried to answer this question. Following them, a conceptual break happens : Christendom invented sin. When evil became sin, man became liable and guilty. It is now a matter of liberty : man wants evil. After them, some philosophers will keep to work on the subject of the bad will. Our purpose is to find the story of these concepts and to connect thoughts between themselves. Evil has been made by this story and brings many anthropological consequences : man understands himself through evil. Wickedness is not just a matter to solve, wickedness becomes a way to define mankind. We want to show that wickedness issue is the foundations of morality and how it makes us see and think human will. Several stages occurred in this philosophical evolution. Every ethic deals with evil, not all put it at the heart of their system. Our first stage is Antiquity. Plato brings the ideas of God and perfect world in philosophy but faces the riddle of our crimes. His theodicy adopted by Plotinus and Stoics will always refuse pervert instinct in man. A man who want evil is nonsense. Christian sin appearance changes everything. Augustine will be his strongest defender. By living a double spiritual conversion, he understands wickedness as weakness due to original sin. Man want evil because he is no longer able to will something else. Anselmus follows the dogma of the fall but puts logical and semantic dimension in it and presents a self-interested wickedness. Man wants evil not for itself, man does not want enough good. Our last stage is Kant. Radical will is the first concept which allows to conceive a normal bad will which would evil just because it is one of his options and it has the liberty to do so. We can see the difference between our starting point and our arrival. We see now how the concept of will has grew up and changed. Little by little, will comes from darkness to light. The more will faces obstacles, the more it is obvious. Thinking on evil is the archaeology of the will.
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Playing dead : living death in early modern dramaAlsop, James January 2014 (has links)
This thesis looks at occurrences of "living death" – a liminal state that exists between life and death, and which may be approached from either side – in early modern English drama. Today, reference to the living dead brings to mind zombies and their ilk, creatures which entered the English language and imagination centuries after the time of the great early modern playwrights. Yet, I argue, many post-Reformation writers were imagining states between life and death in ways more complex than existing critical discussions of “ghosts” have tended to perceive. My approach to the subject is broadly historicist, but informed throughout by ideas of stagecraft and performance. In addition to presenting fresh interpretations of well-known plays such as Thomas Middleton’s The Maiden’s Tragedy (1611) and John Webster’s The White Devil (1612), I also endeavour to shed new light on various non-canon works such as the anonymous The Tragedy of Locrine (c.1591), John Marston's Antonio's Revenge (c.1602), and Anthony Munday's mayoral pageants Chruso-thriambos (1611) and Chrysanaleia (1616), works which have received little in the way of serious scholarly attention or, in the case of Antonio's Revenge, been much maligned by critics. These dramatic works depict a whole host of the living dead, including not only ghosts and spirits but also resurrected Lord Mayors, corpses which continue to “perform” after death, and characters who anticipate their deaths or define themselves through last dying speeches. By exploring the significance of these characters, I demonstrate that the concept of living death is vital to our understanding of deeper thematic and symbolic meanings in a wide range of dramatic works.
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O DIABO ESTÁ ENTRE NÓS: o discurso da Igreja Universal do Reino de Deus e o processo de demonização dos cultos afro-brasileiros em São Luís, MA (1992 - 2017). / El DIABLO ESTÁ ENTRE NOSOTROS: el discurso de la Iglesia Universal del Reino de Dios y el el proceso de demonización de los cultos afro-brasileños en São Luís, MA (1992 - 2017). / THE DEVIL IS BETWEEN US: the discourse of the Universal Church of the Kingdom of God and the process of demonization of Afro-Brazilian cults in São Luís, MA (1992 - 2017).PESTANA, Isa Prazeres 10 July 2017 (has links)
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Isa Prazeres Pestana.pdf: 1967644 bytes, checksum: 126e377e02ce70433d5512a91248e655 (MD5)
Previous issue date: 2017-07-10 / Este estudio tiene como objetivo analizar el discurso y las prácticas religiosas de la Igreja
Universal do Reino de Deus, destacando la guerra contra el diablo y el proceso de
demonización de los cultos afro-brasileños, en el período entre 1992 - en la primera edición
del diario Folha Universal y 2017 - año de la realización de las entrevistas. Además, se busca
comprender la figura del diablo en el imaginario cristiano, que tuvo presencia marcada desde
el período medieval y resurge como elemento central en el discurso de la Igreja Universal en
el siglo XX, período analizado por algunos investigadores como: de la secularización y del
desencanto. Las fuentes utilizadas durante la investigación fueron orales (entrevistas),
documentación escrita (periódicos, procesos, publicaciones), bibliografía especializada sobre
la temática. / This study aims to analyze the discourse and religious practices of the Church
Universal of the Kingdom of God, highlighting the war against the devil and the
demonization of Afro-Brazilian cults, in the period between 1992 - in the first edition
of the newspaper Folha Universal and 2017 - year of the interviews. In addition, we are looking for
understand the figure of the devil in the Christian imaginary, which had a marked presence since
the medieval period and resurges as a central element in the discourse of the Universal Church in
the twentieth century, a period analyzed by some researchers such as: secularization and
disenchantment The sources used during the research were oral (interviews),
written documentation (newspapers, processes, publications), specialized bibliography on
thematic. / Este estudo tem como objetivo analisar o discurso e as práticas religiosas da Igreja Universal
do Reino de Deus, destacando a guerra contra o diabo e o processo de demonização dos cultos
afro-brasileiros, no período compreendido entre 1992 – ano da primeira edição do jornal
Folha Universal e 2017 – ano da realização das entrevistas. Além disso, busca-se
compreender a figura do diabo no imaginário cristão, que teve presença marcada desde o
período medieval e ressurge como elemento central no discurso da Igreja Universal no século
XX, período analisado por alguns pesquisadores como: da secularização e do
desencantamento. As fontes utilizadas durante a pesquisa foram orais (entrevistas),
documentação escrita (jornais, processos, publicações), bibliografia especializada sobre a
temática.
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Acting and its refusal in theatre and film.McCurdy, Marian Lea January 2014 (has links)
This thesis examines works of theatre and film that explore a refusal of acting. Acting has traditionally been considered as something false or as pretending, in opposition to everyday life, which has been considered as something real and truthful. This has resulted in a desire to refuse acting, evident in the tradition of the anti-theatrical prejudice where acting is considered to be seductive and dangerous. All the works that I examine in this thesis are relatively recent and all of them explore the paradox that in our (postmodern) times a gradual reversal has occurred where everyday life is seen as more and more false or as pretending or simulating (ie. containing acting and theatricality) and conversely, acting in theatre and film has become the place where people have begun searching for reality and truth and where ‘acting’ and pretending in life can be revealed and refused. The result of this paradox - and what I also discuss as a confusion of acting and living - is that the place in which acting can be refused has shifted; the ethical desire to refuse acting (in theatre and in life) is turning up in the aesthetic domain of acting itself.
In my first chapter I study works by filmmaker István Szabó and playwright Werner Fritsch, who represent the desire to refuse acting in the context of fascism where theatrical and filmic spectacle was used by the Nazis to seduce the population and where actors during this period also experienced an inability to separate their political and artistic lives. In my second chapter I look at the way Genet’s The Balcony and Ang Lee’s Lust, Caution explore the desire to refuse acting as a result of a confusion of acting and living in the context of sexual (sadomasochistic) role-play. And in my third chapter I examine the way Warhol’s The Chelsea Girls, von Trier’s The Idiots and Affleck’s I’m Still Here represent a refusal of acting and theatricality altogether, responding to the way that ‘acting’ in life may have become an all-pervasive substitute (a simulation) for living. Foundational to the development of this thesis and a major source of material is my analysis of three theatrical productions with Free Theatre Christchurch, directed by Peter Falkenberg, in which I was involved as an actor and in which a refusal of acting was explored.
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Investigating the prevalence of Satanism in Zambia with particular reference to the Kabwe districtKayuni, Hachintu Joseph 04 1900 (has links)
This study examined the alleged prevalence of Satanism in Zambia, with a particular reference to the Kabwe District during the period 2010-2013. The overall objective was to ascertain the claims and speculations on the alleged prevalence of Satanism in the district of Kabwe.
The claims about the alleged prevalence of Satanism and the satanic scare were found by this study to be a reality in Kabwe, with eighty-eight per cent (88%) of the respondents acknowledging the alleged prevalence of the phenomenon. People’s knowledge of Satanism was mainly through rumours, messages from Churches and the electronic media. Studies on rumours (by Stephen Ellis, Gerrie Ter Haar and Jeffrey Victor) have shown that rumours can be investigated in the search for facts, especially rumours that offer plausible explanations for people’s shared anxieties. The above mentioned scholars argue that with efforts at corroboration, such as by interviewing key informants, the researcher can seek credibility on prevailing rumours by verifying or dismissing mere rumours from true stories.
The assertions from scholars above justified the use of rumours as a methodological tool in this study. From sources of information the study relied on, claims about the alleged prevalence of Satanism in the district were investigated. The study refuted the satanic claims in a number of cases that were analysed, because they were mostly based on ‘pious legends’ hence lacked objective evidence. From the few incidents that suggested the prevalence of Satanism, there were still two basic problems faced in assessing their credibility: the first being the difficulty in determining the reliability of the confessions from informants who in this case either claimed they were ex-Satanists or served on behalf of Satanists. The second problem consisted in what seemed to be the inconsistency in the explanations of motives behind human killings found in the ritual murders. Some explanations did not suggest satanic motives.
One example of refuted claims concerned the two locations within Kabwe district which were highly rumoured to be sites for Satanists, which were found by this study to be Freemasonry Lodges, contrary to what was rumoured.From the findings of this study, it was believed that people joined Satanism either because of the greedy for riches or to avoid poverty. It was also believed that other peoples joined Satanism unconsciously through luring methods used by Satanists.
The study also found the satanic scare to have effects on the lives of people in the district. For example, it caused some people to become more committed Christians in their defence against the alleged satanic forces. Because people had associated riches to Satanism, certain individuals avoided getting rich for fear of being labelled ‘Satanists’. / Religious Studies and Arabic / D. Litt. et Phil. (Religious Studies)
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