This study examines the traditional claim that in 1903, while an employee of the Edison Manufacturing Company, Edwin Stanton Porter discovered the principle of editing construction which made possible the fictional motion picture narrative. It will show that Edison studio policy in the period would have discouraged such an achievement and that the crucial first step in the elaboration of the early film narrative was the development of a compositional aesthetic derived from the staged or 'fake' newsreel. Based on that aesthetic between 1904 and 1907 film directors including Edwin Porter turned out a short-lived, tableau-action narrator-dependent story film in actuality style that became the basis of the nickelodeon boom dating from 1906. The social and industrial pressures engendered by that success led to the fragmentation of the complete action tableau and the displacement of the tableau narrative by a shot-dependent, autonomous narrative constrained by the formal features of actuality composition. The final chapter analyzes a leading example, the 1907 emergence of parallel editing in the production of one-reel screen tales of last-minute rescue.

Mitochondrial gene expression in trypanosomatid pathogens requires extensive post transcriptional modification called RNA editing. This unique molecular mechanism, catalyzed by a multiprotein complex (the editosome), generates translatable transcripts for essential components of parasite respiratory complex. How editosome proteins are assembled and perform RNA editing is not fully understood. Moreover, previous studies have shown that editosome proteins are essential for parasite survival, which makes editosome as a suitable target for drug discovery. Currently, researchers use radio-labeled based assays to monitor RNA editing process. However, these assays are not suitable for high throughput screening of editosome inhibitors, have low detection limits, and cannot monitor RNA editing in real time. / Therefore, to develop a sensitive high throughput RNA editing assay, we have designed a sensitive hammerhead ribozyme-based fluorescence assay. Ribozyme structure was remodeled by adding or removing uridylate in its conserved catalytic core to make an inactive ribozyme. In the presence of the editosome, inactive ribozyme is edited to an active ribozyme. Consequently, hammerhead ribozyme activity can be measured by cleaving its fluorescently labeled substrate. We have shown that higher sensitivity is achieved using fluorescent based assay than conventional radio-labeled assay. Moreover, we can use this assay for rapid identification and characterization of the editosome inhibitors against RNA editing activities in trypanosomatids.

PLA (Atkarpomis tiesinių agregatų) formalizavimo metodas gali būti naudojamas sistemų formalių specifikacijų sudarinėjimui. Sistemų formalios specifikacijos gali būti užrašomos tekstiniu pavidalu, tačiau tai yra labai varginantis procesas, ko pasėkoje gautas rezultatas yra vaizdiniai neinformatyvus ir vartotojai negali lengvai perprasti sistemos specifikacijos. Šiame dokumente pateikiamas būdas vizualiai ir pakankamai lengvai užrašyti sistemų formalias specifikacijas naudojant PLA formalizavimo metodą. Šiame dokumente taip pat pristatomas grafinis redaktorius – sudėtingų formalių specifikacijų integruotos analizės automatizavimo sistemos posistemė, skirta agregatinių specifikacij�� kūrimui ir redagavimui. / PLA method can be used to formally specify systems. Systems specifications are written as text, what is exhaustive and understandable, but unfortunately are not visual, and user can’t quickly acquaintance with the formalized system. This article presents a way to visually and quite easily write systems specifications using PLA formalization method. This article also presents a software tool to accomplish this task. That’s graphical editor – a subsystem of a formal complex systems integrated analysis automatization system (FSA).

Modern head in these days can‘t even imagine his life without a computer. Since the day of the first computer was created software companies like Microsoft, Apple and other are trying to make computer software faster, more stable, reliable and easier to understand. Faster micro processors enables graphic projection, three dimensional modeling or just graphical edition programs to run fast enough on home computers. System and graphical processors are getting faster and faster. In our days the ability to draw very complex three-dimensional worlds in the real time became a reality. Everyone knows that such worlds are made of many models coated with textures. There are many texture generation, creation and edition programs in today’s market. Textures are very popular between web and all other graphic and computer model creators. Texture makes a big sense in web design and computer model creation. Wrong texture color or pattern can make a website or a computer model look poorly. The same texture could look differently according to the properties, that have been applied to the surface of an object. If bump map property is used, we will get a different looking object. These palters are used in new games, who exploits much of the graphical card features. Reaching to find out better graphical object creation possibilities, it’s visualization and concretely – textures, I was working on two-dimensional and three-dimensional modeling programs. In analytical part you can find some... [to full text]

One approach to manage collections is to create data about the things in it. This descriptive data is called metadata, and this term is in this thesis used as a collective noun, i.e no plural form exists. A library is a typical example of an organization that uses metadata, to manage a collection of books. The metadata about a book describes certain attributes of it, for example who the author is. Metadata also provides possibilities for a person to judge if a book is interesting without having to deal with the book itself. The metadata of the things in a collection is a representation of the collection that is easier to deal with than the collection itself. Nowadays metadata is often managed in computer-based systems that enable search possibilities and sorting of search results according to different principles. Metadata can be created both by computers and humans. This thesis will deal with certain aspects of the human activity of creating metadata and includes an explorative study of this activity. The increased amount of public information that is produced is also required to be easily accessible and therefore the situation when metadata is a part of the Semantic Web has been considered an important part of this thesis. This situation is also referred to as the Web of Data or Linked Data. With the Web of Data, metadata records living in isolation from each other can now be linked together over the web. This will probably change what kind of metadata that is being created, but also how it is being created. This thesis describes the construction and use of a framework called Annotation Profiles, a set of artifacts developed to enable an adaptable metadata creation environment with respect to what metadata that can be created. The main artifact is the Annotation Profile Model (APM), a model that holds enough information for a software application to generate a customized metadata editor from it. An instance of this model is called an annotation profile, that can be seen as a configuration for metadata editors. Changes to what metadata can be edited in a metadata editor can be done without modifying the code of the application. Two code libraries that implement the APM have been developed and have been evaluated both internally within the research group where they were developed, but also externally via interviews with software developers that have used one of the code-libraries. Another artifact presented is a protocol for how RDF metadata can be remotely updated when metadata is edited through a metadata editor. It is also described how the APM opens up possibilities for end user development and this is one of the avenues of pursuit in future research related to the APM. / <p>QC 20141028</p>

The restoration of Gregorian chant throughout the nineteenth century culminated in the publication of new official Vatican chant books, particularly the Graduale Romanum of 1908. Major contributions were made by the monks at the abbey of Solesmes, who focused on the oldest available medieval manuscripts, and by scholars in the Cecilian movement, who favored sources compiled after the Middle Ages. These two viewpoints were fused into the Graduale Romanum to create a comprehensive historical perspective. To support this position, this thesis traces historical events and conflicts leading up to the publication of the Graduale Romanum. It also compares the Graduale Romanum with its most immediate source, the 1895 Liber Gradualis by Solesmes, focusing on the Propers of the four Sundays of Advent. Analysis of the differences between the two reveals that the Graduale Romanum closely resembles medieval manuscripts and reflects Renaissance and nineteenth-century sources to a limited degree. / The graduale romanum of 1908 : an exposition -- Toward a new edition of chant -- Graduale romanum and Liber gradualis compared -- Conclusions and proposals for further study. / School of Music

Fourteen Malawian news editors Q-sorted fifty-four stories under two situations: their real environment which is a developmental press system, and a hypothetical ideal situation emulating a western libertarian system. The Qconcourse was constructed using eighteen news value combinations developed by Water Ward through a 3x3x2 factorial design. The stories were sorted along an eleven point bi-polar continuum from "most likely to use" to "least likely to use."The study showed that in an ideal situation, all Malawian editors selected stories with conflict, known principal and impact. In their own situations, the editors split into two: Pro-government Editors who selected known principal, conflict and magnitude stories; and Privatelyowned Newspaper Editors who valued known principal and impact, followed by conflict and oddity. Despite the use of these news elements, the study showed that environmental factors in their own situations such as organizational policy and ownership also influenced story choices. Progovernment Editors would rather use a "normality" story, than use one with conflict, impact and known principal, but speaking ill of government. / Department of Journalism

Diss. (sammanfattning) Stockholm : Stockholms universitet, 2007. / Härtill 4 uppsatser.

Thesis (Ph. D.)--Ohio State University, 2007. / Title from first page of PDF file. Includes bibliographical references (p. 139-161).

Thesis (Ph. D.)--University of Washington, 1998. / Vita. Includes bibliographical references (leaves [87]-96).