Theoretical part of dissertation was written on the basis of studying professional literature. It provides overview of Scabies disease, its epidemiological incidence, transmission, clinical course, diagnostics and also of its treatment. Practical part was formed retrospectively by qualitative research and secondary data analysis. These data were collected from different publications from the State Health Institute in Prague and the Health Information and Statistics Institute in the Czech Republic. The main aim of this dissertation was analyzing the trend of scabies incidence in the Czech Republic within ten years period (2003 2012). Moreover the practical part of this dissertation contains information related to trends of scabies incidence in individual districts of the Czech Republic depending on age, sex, team, seasonal index, or epidemiological scabies incidence as occupational disease. Linear regression was used to assess the incidence trend. Subsequently correlations were ascertained by using method of correlation coefficient calculation. In the research it was found that registered scabies incidence seems to more likely be decreasing from the beginning of followed period (i.e. from the beginning of 2003). According to the seasonal index the most common incidence of this disease within followed period was in October. On the other hand the lowest scabies incidence was in June. The highest sickness rate was recorded in the district Ústí nad Labem with almost 50 cases per 100 000 inhabitants. Scabies as occupational disease belongs to the most common recorded transmissible and parasitic disease in the Czech Republic, mainly at nurses in the hospitals, attendants in retirement homes, in internal wards and in social care institutes. The highest incidence rate was notified in age categories from 5 to 9 years. There exists strong positive linear correlation between scabies incidence and age. Epidemiological scabies incidence in the Czech Republic had two main peaks during period 1965 2012, in 1970 and 1993.