The aim of the diploma thesis is to describe and analyse information sources, which are useful for the molecules portfolio selection suitable for the future development of a generic drug. These information sources should be examined on the case study of the portfolio selection in a given therapeutic area. The topic of the diploma thesis is presented in the context of basic principles and functions of the generic farmaceutical industry and its information needs. The introductory chapter characterizes the farmaceutical industry in general and warn on a competitive environment, which the farmaceutical companies can succeed in thanks to the advanced methods of the business intelligence. The second chapter focuses on the differences betwen the generic and original pharmaceutical industry, a drug lifecycle is also introduced there. The next chapter specifies the methods of the business intelligence in the generic pharmaceutical industry on the ground of its information needs. The fourth chapter plays a key role. First of all, it introduces general characteristics of information sources used in the strategic portfolio management. Secondly, the detailed description and analysis of eight main information sources used by the generic companies within business intelligence follows. In the last chapter these...

The aim of the diploma thesis is to describe and basically analyze representative databases and digital libraries that focus on pharmaceutical disciplines. The introductory chapter is concerned with related terminology, while the following chapters refer to significant subjects and principles in the field of pharmaceutical industry, and also to important classification systems and retrieval languages that can be found in some of the described resources. The fifth chapter focuses on pharmaceutical information resources which are offered by some of the world's leading database service companies. The sixth chapter contains a description and a basic analysis of 10 representative electronic resources for pharmaceutical disciplines. The empirical section of this diploma thesis consists of three major parts. One of them is a subject coverage analysis of bibliographic databases MEDLINE and EMBASE from the viewpoint of pharmaceutical information. Secondly, it contains a presentation of an indicative survey that is related to using electronic information resources by a commercial and a nonprofit subject. The last chapter deals with information brokering that is presented on example of the Medistyl company. Keywords Pharmaceutical industry, pharmacy, pharmacovigilance, factographic databases, bibliographic...