This masters thesis deals psychosocial specifics of patients with multiple sclerosis. My study consists of five main parts. In the first part I am discussing multiple sclerosis, the special emphasis placed on physical changes. In the second part I am discussingp sychosocial specifics of patients with multiple sclerosis. I try to show the wide complexity of the MS problem. In the third part I showing case studies of five patients with MS. In fourth I am discussingsocial system in Czech Republic, in the main support for patients with MS. In the last part I try to acquainted with the research results "Psychosocial Support for Patient with MS".