The aim of the study is to compare the ergonomic characteristics of swiveling forwarder cab with standard fixed cab. There are compared data measured during the operator's workshift inside both types of cabs. Part of the operator's shift proceeded after dark, while the effect of different workload and two different types of reflectors was evaluated. Additional reference measurements were carried out during the work with the simulator of harvester technology. The measured data representing the progress of physiological functions of the operator, responsive to the degree of the workload. A prerequisite is a system and an integrative approach and orientation about how interdisciplinary processing, in particular with regard to link topics, such as health and safety at work, stress and strain. The contents of the theoretical part of the work gives an overview of the background and the most important knowledge on the basis of study and analysis of available relevant literature of our and foreign provenance, formulates hypotheses basic research assumptions and the method of authentication. Data obtained using the measuring apparatus Biofeedback 2000 x-pert are evaluated in the practical part. The intention of the discussion is to compare the results with data in the literature, indicate the open questions and options of the application. The conclusions are incorporated into a broader context and compared with available literature.

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This thesis explores the human body on the basis of its anatomical disposition in connection with the functional principles which enable to develop the correct body posture, leg position en dehors, classical dance poses and coordination of movement leading to rotation and jump. In this thesis, I look upon the human body as the main dancer´s tool allowing to perform the classical dance technique and by the described functional principles, I attepmt to support the correct execution of individual parts of the classical dance technique. In conclusion of this thesis, I comment on general employing of these functional principles in classical dance lessons.

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Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Pharmacology & Toxicology Student: Klára Bechná Supervisor: Přemysl Mladěnka, PharmD., Ph.D. Title of diploma thesis: Copper and its pato/physiological importance in human organism Copper is an indispensable trace element of our organism. This thesis summarizes the current knowledge about copper, its role in the human body and diseases connected with copper dysbalance. The first part of the thesis deals with the physiological aspects. Functions of copper in the body are described here in detail, in particular the structure and properties of copper- containing enzymes - so-called cuproenzymes. The next section summarizes the current knowledge of the kinetics of copper in the body at the cellular and whole-body levels, including interactions with other trace elements. Details are also presented for each of the factors involved in the homeostasis of copper in the human organism. The second part of the thesis deals with patophysiology of copper. It is focused on the most important diseases that are directly linked to disorders of copper homeostasis in the organism. The greatest emphasis is given mainly on two of them - Wilson's disease and Menkes disease. The former is associated with an excess of copper in the body while...

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