v, 144 leaves : ill. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Thesis (Ph.D.)--University of Adelaide, Dept. of Medicine, 1971

Thesis (Ph.D.) -- University of Adelaide, Dept. of Medicine, 1971.

Thesis (Ph. D.)--University of Chicago, 1917. / "Private edition, distributed by the University of Chicago libraries, Chicago, Illinois." "From the Hull Physiological Laboratory of the University of Chicago." "Reprinted from the American journal of physiology, vol. 55, nos. 2 and 3, March and April, 1921." Bibliography at end of each study.

Salmonella species are among the major foodborne intestinal pathogens that are of public concern with respect to food safety. The ability of intestinal pathogens to resist gastric acidity corresponds to their oral infective dose (ID). The survival and lipopolysaccharide (LPS) profiles of Salmonella typhimurium grown at different pH values and to different phases of growth were examined in simulated gastric fluid (pH 1.5), ileal fluid (pH 7.0), colon fluid (pH 8.0). The survival and growth of S. typhimurium were also examined during sequential passage through all three fluids. Viable cells were rapidly reduced from 106 CFU.ml-1 to <10 CFU.ml-1 within 4 min in gastric fluid. Cells inoculated directly into ilea] and colon fluids survived and multiplied extensively. When low numbers of viable cells of Salmonella in contact with gastric fluid (0.5 min of contact) were transferred sequentially to ileal and colon fluids, only the early and late stationary phase cells were capable of recovery and growth to high numbers. The harsh environment of the gastric fluid did not change the LPS profiles of the inoculated Salmonella cells. Entrapment of S. typhimurium in calcium alginate beads and chocolate increased its survival in gastric fluid. This implies that Salmonella cells are protected from killing when ingested with food. These results may explain why Salmonella species have a very low ID when consumed as part of some contaminated food sources.

Akademische Habilitationsschrift zur Erlangugng der Venia legendi für innere Medicin--Hohen medicinischen Facultät der Universität Breslau. (Opponenten: Dr. R. Stern ... Dr. A. Tietze). / "Literatur": p. 41-43.

Thesis--University of Pennsylvania.

Thesis--University of Pennsylvania.

Thesis (M.D.)--University of Pennsylvania, 1802. / Includes bibliographical references. Microform version available in the Readex Early American Imprints series.

Thesis (M.D.)--University of Pennsylvania, 1803. / Microform version available in the Readex Early American Imprints series.

Inaug.-Diss.--Giessen. / Lebenslauf. "Beiträge zur chemischen physiologie und pathologie ... Sonder-abdruck aus Band VII, Heft 1/3." "Literaturverzeichnis": p. 35.