Background: The gearbox and machinery faults prediction are expensive both in terms of repair and loss output in production. These losses or faults may lead to complete machinery or plant breakdown.  Objective: The goal of this study was to apply advanced machine learning techniques to avoid these losses and faults and replace them with predictive maintenance. To identify and predict the faults in industrial machinery using Machine Learning (ML)  and Deep Learning (DL) approaches.  Methods: Our study was based on two types of datasets which includes gearbox and rotatory machinery dataset. These datasets were analyzed to predict the faults using machine learning and deep neural network models. The performance of the model was evaluated for both the datasets with binary and multi-classification problems using the different machine learning models and their statistics. Results: In the case of the gearbox fault dataset with a binary classification problem, we observed random forest and deep neural network models performed equally well, with the highest F1-score and AUC score of around 0.98 and with the least error rate of 7%.  In addition to this, in the case of the multi-classification rotatory machinery fault prediction dataset, the random forest model outperformed the deep neural network model with an AUC score of 0.98.  Conclusions: In conclusion classification efficiency of the Machine Learning (ML) and Deep Neural Network (DNN) model were tested and evaluated. Our results show Random Forest (RF) and Deep Neural Network (DNN) models have better fault prediction ability to identify the different types of rotatory machinery and gearbox faults as compared to the decision tree and AdaBoost.  Keywords: Machine Learning, Deep Learning, Big Data, Predictive Maintenance, Rotatory Machinery Fault Prediction, Gearbox Fault Prediction, Machinery Fault Database, Internet of Things (IoT), Spectra quest machinery fault simulator, Cloud Computing, Industry 4.0

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