The aim of this study is to find out the main psychological problems of inner migrants’ children in Guiyang and to give some suggestions to treat these problems. Compared to other social groups, inner migrants’ children meet specific psychological issue in migrate processing. It is a world-wide issue, especially in the developing countries today. In this research, both qualitative method and quantitative one are used. The research result shows that there are three aspects that influence the psychological condition of the inner migrants’ children most. They are social-economic condition of the family, school environment, and social policy.