- About
-
The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
provided by the
Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
Search results
Showing 1 to 10 of 12 (0.078 seconds)Spelling suggestions: "subject:"hypercholesterolemia"" "subject:"hypercholesterolemic""
| 1 |
Pediatric implications of heterozygous familial hypercholesterolemiaWiegman, Albert, January 1900 (has links)
Proefschrift Universiteit van Amsterdam. / Met lit. opg. - Met samenvatting in het Nederlands.
|
| 2 |
Familial hypercholesterolemia in childhoodJongh, Saskia de, Bor, Chris. January 1900 (has links)
Proefschrift Universiteit van Amsterdam. / Met lit. opg. - Met samenvatting in het Nederlands.
|
| 3 |
Genetics and therapy of familial hypercholesterolemiaSauvage Nolting, Pernette Régine Wilhelmine de, Bor, Chris. January 1900 (has links)
Proefschrift Universiteit van Amsterdam. / Met lit. opg. - Met samenvatting in het Nederlands.
|
| 4 |
Genetic insights, clinical efficacy and practical implications of genetic screening for familial hypercholesterolemiaUmans-Eckenhausen, Marina Adriana Wilhelmina, January 1900 (has links)
Proefschrift Universiteit van Amsterdam. / Met lit. opg. - Met samenvatting in het Nederlands.
|
| 5 |
Familial hypercholesterolemia the determination of phenotype /Jansen, Angelina Cornelia Maria, January 1900 (has links)
Proefschrift Universiteit van Amsterdam. / Auteursnaam op omslag: Angelique Jansen. Met lit. opg. - Met samenvatting in het Nederlands.
|
| 6 |
Aggressive lipid lowering in patients with familial hypercholesterolaemiaWissen, Sanne van, January 1900 (has links)
Proefschrift Universiteit van Amsterdam. / Met lit. opg. - Met samenvatting in het Nederlands.
|
| 7 |
Familial hypercholesterolemia in childhood diagnostics, therapeutical options and risk stratification /Rodenburg, Jessica, January 1900 (has links)
Proefschrift Universiteit van Amsterdam. / Met lit. opg. - Met samenvatting in het Nederlands.
|
| 8 |
Metabolic and vascular dysfunction during hyperglycemia induces inflammation the role of the endothelial glycocalyx on vascular homeostasis in vivo /Nieuwdorp, Max, January 1900 (has links)
Proefschrift Universiteit van Amsterdam. / Met een samenvatting in het Nederlands.
|
| 9 |
Četnost vybraných genetických polymorfismů cytochromu P450 v české populaci a vliv genotypu CYP2C9 na hypolipidemické působení fluvastatinu / Frequency of selected genetic polymorphisms of cytochrome P450 in the Czech population and the influence of CYP2C9 genotype on the hypolipidemic effect of fluvastatinBuzková, Helena January 2012 (has links)
55 Abstract Frequency of selected genetic polymorphisms of cytochrome P450 in the Czech population and the influence of CYP2C9 genotype on the hypolipidemic effect of fluvastatin Introduction: One of the main factors of genetically determined variability in response of humans to administered drugs are differences in catalytic activity of metabolizing enzymes, which are caused mainly by genetic polymorphisms in cytochrom P450 family enzymes. This thesis consists of two parts and it is presented as a commentary to the original papers. The first aim was to investigate the frequency of functionally important variant alleles of three main isoenzymes of cytochrome P450 gene: CYP2D6, CYP2C9, CYP2C19, throughout the Czech population, predict the prevalence of poor metabolizer phenotypes, and then to compare the results to the data from other populations. Secondly, we analysed the correlation between the CYP2C9 genotype and cholesterol-lowering effect of fluvastatin in human hypercholesterolemic patients. Methods: Genotypes were determined by PCR-RFLP. The presence of alleles CYP2D6*1, *6, *5, *4, *3, and gene duplication was analysed in 233 healthy volunteers, CYP2C9*1, *2 and*3 in 254 subjects and CYP2C19*1, *2 and *2 in 218 subjects. Eighty seven patients on fluvastatin therapy, and 48 patients on monotherapy...
|
| 10 |
Četnost vybraných genetických polymorfismů cytochromu P450 v české populaci a vliv genotypu CYP2C9 na hypolipidemické působení fluvastatinu / Frequency of selected genetic polymorphisms of cytochrome P450 in the Czech population and the influence of CYP2C9 genotype on the hypolipidemic effect of fluvastatinBuzková, Helena January 2012 (has links)
55 Abstract Frequency of selected genetic polymorphisms of cytochrome P450 in the Czech population and the influence of CYP2C9 genotype on the hypolipidemic effect of fluvastatin Introduction: One of the main factors of genetically determined variability in response of humans to administered drugs are differences in catalytic activity of metabolizing enzymes, which are caused mainly by genetic polymorphisms in cytochrom P450 family enzymes. This thesis consists of two parts and it is presented as a commentary to the original papers. The first aim was to investigate the frequency of functionally important variant alleles of three main isoenzymes of cytochrome P450 gene: CYP2D6, CYP2C9, CYP2C19, throughout the Czech population, predict the prevalence of poor metabolizer phenotypes, and then to compare the results to the data from other populations. Secondly, we analysed the correlation between the CYP2C9 genotype and cholesterol-lowering effect of fluvastatin in human hypercholesterolemic patients. Methods: Genotypes were determined by PCR-RFLP. The presence of alleles CYP2D6*1, *6, *5, *4, *3, and gene duplication was analysed in 233 healthy volunteers, CYP2C9*1, *2 and*3 in 254 subjects and CYP2C19*1, *2 and *2 in 218 subjects. Eighty seven patients on fluvastatin therapy, and 48 patients on monotherapy...
|
Page generated in 0.1205 seconds