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The role of proline in osmoregulation by a streptomyceteWood, Nicholas James January 1996 (has links)
No description available.
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Palladium complexes of imino acidsFreund, Kurt Alfredo 01 January 1969 (has links) (PDF)
The nature of this study involves the preparation of coordination compounds of palladium (II) and three imino acids, namely pipecolinic acid, pyrrolidine-20Carbozylic acid and azetidine carboxylic acid.
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Mechanistic Investigation of the Flavin-Neighboring Residues S45, A46 and I335 in Pseudomonas aeruginosa D-arginine DehydrogenaseOuedraogo, Daniel, Gadda, Gioavanni 16 December 2015 (has links)
Pseudomonas aeruginosa ᴅ-arginine dehydrogenase (PaDADH) is a flavin-dependent enzyme. The enzyme catalyzes the oxidative deamination of a broad range of ᴅ-amino acids to their corresponding imino-acids, which are non-enzymatically hydrolyzed to α-keto-acids and ammonia. A46, S45 and I335 residues are located in flexible loops, which form a flask-like substrate-binding pocket. In this study, I335, A46, and S45 were mutated to histidine, glycine, and alanine, respectively and individually, through site-directed mutagenesis, to investigate their role in binding and catalysis in PaDADH. The results showed that A46 and S45 residues participate in the optimal orientation of the substrate α-amino group and I335 modulate the active site flexibility.
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