Treatment of severe acute pancreatitis is considered to be conservative. The only generally accepted indication for surgery in severe acute pancreatitis patients is an established infection of the necrotic tissue and persisting or progressing symptoms of multiorgan failure despite the maximal intensive treatment. For surgical treatment are also indicated patients with complications of severe acute pancreatitis (erosive hemorrhage, perforation of GIT etc.). In the proposed work, attention is drawn to those cases, where the general condition of the patient deteriorates combined with a progression of ACS and where a decompressive laparotomy can improve the prognosis of the disease. In our group of 214 patients with severe acute pancreatitis, who were treated over the last six years, 70 patients were indicated for surgery. Out of this count, in 17 cases the indication for decompressive laparotomy was a raise of intraabdominal pressure up to the values of ACS together with the symptoms of organ dysfunction, 6 patients died and 11 younger patients survived.

This thesis evaluates the possibility of using objective measurements to assess the postural function of abdominal muscles. The theoretical part provides an overview of findings regarding postural function of the abdominal muscles and the context for their co-activation using intra-abdominal pressure. The results are summarized in the form of research studies relating postural function and low back pain (LBP). The overview of the methods used to measure intra-abdominal pressure and the abdominal muscle activity is the main focus. In this section, we present a new methodology for measuring the activity of the abdominal muscles by using pressure sensors attached to the abdominal wall in the areas of the groin and the lumbar triangle. Methodology: In the experimental part, we tested 35 healthy subjects (average age 21.26t, SD ± 1,62) in 3 posturally different seated scenarios: 1. resting breathing, 2. with added external load (the subjects held a dumbbell 20% of their body weight) and 3. with maximum voluntary increase in intra-abdominal pressure (the diaphragm test). Results: An independent samples t-test indicated that the pressure created by the abdominal wall for both sensors in situation resting breathing increases in situation external load (HA1: upper sensor p=0.0079, lower sensor p=0.0009). We...