The functioning of maxillofacial complex as a one unit is an important condition of fulfilling several functions connected with this area of human body. A maxillofacial region and other parts of the body are connected through occlusion, one of the basic characteristics of which is occlusal plane. According to the number of researchers, 3D orientation of occlusal plane, its shape and possible deformation can have an influence on other anatomic structures via a system of a complex neuromuscular reactions. This theory assumes that the adjustment of occlusal plane inclination causes redistribution and redirection of the chewing forces in the adjacent structures which will subsequently manifest itself in the adjustment of the tension of different muscles. Aim The aim of an experimental part of the research was to define the influence of occlusal plane inclination on the function of maxillofacial region with the focus of jaw joints and chewing muscles. The next goal was to determine the figures of sagittal and frontal inclination of occlusal plane which can be considered as physiological. Patients and Methods The research was based on the examination of 87 people of both genders, different age groups with a complete set of teeth and without chronic diseases. The participants were divided in two groups...