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Hypoxia and Angiogenesis in IUGRWahlquist, Hanna January 2008 (has links)
<p>BACKGROUND: Intrauterine growth restriction (IUGR) is a condition where the infant fails to reach its genetic growth potential due to numerous factors. IUGR foetuses are associated with high perinatal mortality and morbidity. This study investigated if hypoxia might be involved during gestation, and whether if hypoxia may have an impact on the development of the placenta, through regulation of various angiogenic factors, such as HIF-1_, VEGF, PIGF, VEGFR-1 and CD31. METHOD: Each sample of placental tissue was stained by immunohistochemisty for HIF-1_, VEGF, PIGF, VEGFR-1 and CD31. The intensity of staining was graded and the difference between the normal term placentas and the IUGR term placentas were evaluated. RESULTS: HIF-1_ was found to be upregulated in the normal term placental tissue, and VEGFR-1 was found to be upregulated in the IUGR term placental tissue. The other antibodies did not show any significant difference and PIGF failed to show any positive staining. CONCLUSIONS: Further studies on hypoxia in IUGR would be beneficial.</p>
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Hypoxia and Angiogenesis in IUGRWahlquist, Hanna January 2008 (has links)
BACKGROUND: Intrauterine growth restriction (IUGR) is a condition where the infant fails to reach its genetic growth potential due to numerous factors. IUGR foetuses are associated with high perinatal mortality and morbidity. This study investigated if hypoxia might be involved during gestation, and whether if hypoxia may have an impact on the development of the placenta, through regulation of various angiogenic factors, such as HIF-1_, VEGF, PIGF, VEGFR-1 and CD31. METHOD: Each sample of placental tissue was stained by immunohistochemisty for HIF-1_, VEGF, PIGF, VEGFR-1 and CD31. The intensity of staining was graded and the difference between the normal term placentas and the IUGR term placentas were evaluated. RESULTS: HIF-1_ was found to be upregulated in the normal term placental tissue, and VEGFR-1 was found to be upregulated in the IUGR term placental tissue. The other antibodies did not show any significant difference and PIGF failed to show any positive staining. CONCLUSIONS: Further studies on hypoxia in IUGR would be beneficial.
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Optimering av protokoll för immunhistokemiskfärgning med antikroppen anti-TLR4Jeppsson, Alexander January 2013 (has links)
No description available.
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Analys av leukocytinnehållet i framställd plasmakomponent för transfusionJuma, Mahmoud January 2011 (has links)
No description available.
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Hypoxi men inte frånvaro av glukos, påverkar splitsningen av muterat ISCU : Analys av hur yttre faktorer påverkar splitsning av muterat ISCU som orsakar Linderholms sjukdomMbatudde, Jackie January 2014 (has links)
No description available.
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Metodutveckling och validering av vätskebaserade lungprover, exsudat och buksköljvätskor : – en jämförelse mot den konventionella metodenSjönöst, Line January 2014 (has links)
No description available.
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Sena potentialer och arytmitendens i en grupp patienter med implanterbar defibrillatorHedström, Cassandra January 2017 (has links)
No description available.
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Utveckling av en in vitro-modell för studier av sekundärt immunsvar mot Francisella tularensisElebrink, Johan January 2019 (has links)
No description available.
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Utformning av tabletter med förlängd frisättning av ibuprofenJohansson, Lina January 2019 (has links)
No description available.
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Hållbarhetsstudie av arton analyter i klinisk kemisk vardag : Plasmaprovets hållbarhet i centrifugerade primärrör förvarade vid rumstemperatur och kylaSandström, Martina January 2019 (has links)
No description available.
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