This diploma thesis is focused on the description and implementation of the user interface for the analysis of local DNA structures as a web application in the Vue.js framework. The local structure can be described as an alternative DNA structure which arises in a specific DNA sequence that occurs in important regions of the genome. The first part of the thesis is theoretical and examines the field of DNA research and a description of selected technologies. The second part deals with the implementation and testing of the user interface on specific DNA sequences.

This diploma thesis is focused on the description and implementation of the API wrapper application, which works on top of computational core ibp bioinformatics. The first half of the thesis is focused on the summary of basic knowledge in the field of DNA research, as well as the specification of the problem and description of selected technologies. The other half deals with the actual implementation, distribution, and evaluation of application applicability on specific DNA sequences.