Global ETD Search

1	A little on EDG : the role of the cytoplasmic tail in the function of the LPA₁/Edg2 G protein coupled receptor Severin, Jamie Elizabeth 12 1900 (has links) No description available. Cytoplasm Lysophospholipids
2	In vitro and in vivo pharmacologic evaluation of novel lysophospholipid analogs as anticancer agents Hurh, Eunju. January 2005 (has links) Thesis (Ph. D.)--Ohio State University, 2005. / Available online via OhioLINK's ETD Center; full text release delayed at author's request until 2008 Nov 28 Prostate Lysophospholipids.
3	Novel ether lipids as antineoplastic agents Wan, Jung Wing January 1997 (has links) No description available. 615.1 Alkyl lysophospholipids
4	Lysophosphatidic acid receptors mediate the reduction of rat brain infarct volume Tsai, Ping-Ju 21 July 2011 (has links) Abstract Stroke is a potentially lethal cerebrovascular event. Many research studies devoted to the treatment of stroke. In a recent study, sphingosine-1-phosphate (S1P) has the function of reducing the brain infarct volume. However, no study has yet demonstrated that lysophosphatidic acid (LPA) has this function. LPA and S1P are thought to be the two functionally important LPLs with high structural similarity. Although the neuroprotective function of S1P in TIA rat was confirmed, the effects of LPA on the brain damage after ischemic stroke of animal remain unclear. In this study we evaluated the neuroprotective effects of LPA1/3 receptor agonist (VPC31143; VPC) on rat brains subjecting to permanent middle cerebral artery occlusion (PMCAO). A reliable surgical model of rat PMCAO was first established. Thereafter, the animals were divided into control, vehicle, high-dose VPC, and low-dose VPC groups. The vehicle group received intraperitoneal (i.p.) injection of 3% bovine serum albumin (BSA; 1 ml/kg) 30 minutes after PMCAO surgery. The high-dose VPC and the low-dose VPC group respectively received 0.8 mg/kg and 0.25 mg/kg of i.p. injection of VPC (in 3% BSA) 30 minutes after PMCAO surgery. The mortality rate, infarct volume ratio, and the neurobehavioral outcome were measured 24 hours after PMCAO and statistically analyzed for the difference between treatments. Analyses of the experimental results showed that VPC treatment significantly reduced the mortality rate and the infarct volume ratio of the rats 24 hours after PMCAO. The neurobehavioral scores also showed the improved outcome in stroke rats treated with VPC. The beneficial effect of VPC to the ischemic brain was thought to be mediated through the PI3K signal transduction pathway. Further studies at the transcriptional and the translational levels will further confirm this postulation. ischemic stroke lysophospholipids
5	A functional analysis of the human LPA₁G protein coupled receptor Nguyen, Giang Huong 01 June 2004 (has links) No description available. Lysophospholipids Protein kinases Proteins
6	A functional analysis of the human LPA₁G protein coupled receptor Nguyen, Giang Huong, January 2004 (has links) (PDF) Thesis (M.S. in Bio.)--School of Biology, Georgia Institute of Technology, 2004. Directed by Harish Radhakrishna. / Includes bibliographical references (leaves 55-65).
7	Effect of the atherogenic phospholipid, lysophosphatidylcholine (LPC),on endothelial senescence Ko, Choi-lam., 高彩霖. January 2010 (has links) published_or_final_version / Pharmacology / Master / Master of Medical Sciences Endothelium - Aging. Lysophospholipids.
8	Effect of treatment with lysophosphatidylcholine on vascular reactivity of porcine coronary artery Ngai, Kei-foon., 魏奇寬. January 2010 (has links) published_or_final_version / Pharmacology and Pharmacy / Master / Master of Medical Sciences Coronary arteries. Lysophospholipids.
9	Effects of anticancer alkyl-lysophospholipids on cell death and survival Ruiter, Geert Antony, January 1900 (has links) Proefschrift Universiteit van Amsterdam. / Auteursnaam op omslag: Gerald Ruiter. Met bibliogr., lit. opg. - Met samenvatting in het Nederlands. Lysophospholipids. Celdood. Tumorcellen.
10	Identification of novel lysophospholipid acyltransferases in yeast (LPT1) and humans (LPCAT3) and regulation of triglyceride synthesis in yeast / Jain, Shilpa. Oelkers, Peter. January 2008 (has links) Thesis (Ph.D.)--Drexel University, 2008. / Includes abstract and vita. Includes bibliographical references (leaves 155-172).

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