Thesis (Ph. D.)--University of Alabama at Birmingham, 2008. / Additional advisors: Andy Gannon, John Lawrence, James McClintock, Thane Wibbels. Description based on contents viewed May 29, 2008; title from title screen. Includes bibliographical references.

Thesis (M.S.)--University of Alabama at Birmingham, 2007. / Description based on contents viewed Oct. 3, 2008; title from PDF t.p. Includes bibliographical references (p. 39-53).

Thesis (M.S.)--University of Alabama at Birmingham, 2009. / Title from PDF title page (viewed Sept. 2, 2009). Includes bibliographical references (p. 30-36).

Thesis (M.S.)--University of Alabama at Birmingham, 2009. / Title from PDF t.p. (viewed July 29, 2010). Includes bibliographical references (p. 37-42).

No description available.

Thesis (M.S.)--Georgia Institute of Technology, 2004. / Title from PDF t.p. (viewed on Oct. 28, 2006). Julia Kubanek, Committee Member; Mark Hay, Committee Member; Marc Weissburg, Committee Chair. Includes bibliographical references (p. 47-51).

The structure and gene expression of a number of metallothionein (MT) genes of the sea urchin Lytechinus pictus were characterized. The MT genes in this species are members of a small gene family composed of 7 to 10 copies per haploid genome. A genomic library was constructed and 81 clones containing MT sequences were isolated of which 8 were analyzed. The complete sequence of one clone (LpMT1) and the promoter region of 7 others was determined. LpMT1 encodes a primary transcript of 3042 bp composed of 4 exons which is processed into a mRNA of 605 bases. The promoter regions of all the genes analyzed are highly conserved and contain multiple copies of the metal responsive enhancer element consensus sequence. L. pictus eggs injected with MT promoter fused to a CAT reporter gene, and cultured to various stages of development, directed transcription in a metal inducible fashion. The promoters also direct transcription in the sea urchin Strongylocentrotus purpuratus and in a human HeLa cell line. Deletion analysis indicates that the LpMT1 promoter requires regulatory elements other than the two metal responsive elements.

Thesis (M.S.)--University of Alabama at Birmingham, 2010. / Title from PDF t.p. (viewed July 20, 2010). Additional advisors: Robert U. Fischer, John M. Lawrence, Ken B. Marion. Includes bibliographical references (p. 55-59).

Thesis (M.S.)--University of Alabama at Birmingham, 2009. / Title from PDF t.p. (viewed July 19, 2010). Includes bibliographical references.

Thesis (M.S.)--University of Alabama at Birmingham, 2006. / Description based on contents viewed Jan. 29, 2007; title from title screen. Includes bibliographical references (p. 70-78).