The diploma thesis deals with the investment loan for the business entities and the macroeconomic indicators. The theoretical part provides an overview of the credit process of the investment loan for business entities. The theoretical part focuses on the process of granting the loan, loan contracts and subsequent monitoring of the credit relationship. In the thesis are included the basic characteristics of the most used hedging instrument and the process of assessing the creditworthiness of an applicant. The empirical part of the diploma thesis uses the method of descriptive statistic for analysis examined variables. In the empirical part of the diploma thesis is included the analyse of the dependence between the volume of investment loans and the macroeconomic indicators.