Thesis (M.S.)--University of Wisconsin--Madison. / Typescript. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 24-26).

Thesis (M.D.)--Medical Society of Connecticut, 1810. / Microform version available in the Readex Early American Imprints series.

Thesis (doctoral)--University of Helsinki, 1998.

Thesis (doctoral)--University of Helsinki, 1998.

The physiology of oxygen metabolism in Group B N. meningitidis was investigated. The respiratory components of the electron transport chain included dehydrogenases, ubiquinone, multiple b- and c-type cytochromes, and cytochromes o and a as terminal oxidases. Independent variations in the respiratory components were determined for cells grown under different conditions of iron concentrations and aeration (including anaerobiosis). Studies on oxidase activities in envelope preparations suggested branching of the respiratory chain at the levels of dehydrogenases, cytochrome b and terminal oxidases. Work on L-cysteine oxidase activity associated with the envelope preparations indicated the presence of an additional "alternate" oxidase insensitive to terminal oxidase inhibitors. A soluble CO- and NO-binding c-type cytochrome was shown to be present in the supernatant fluids and might be involved in an ascorbate-TMPD oxidase activity. A model of a branched electron transport system is proposed. The levels of catalase, peroxidase and superoxide dismutase in the organism were shown to vary with the growth conditions.

No description available.