No description available.

The purpose of this study was to evaluate the effectiveness of whole body vibration training (WBVT) as a modality for inducing changes in body composition and muscular strength in sedentary, overweight/obese post-menopausal women. The WBVT program was compared to other training regimens commonly used as weight loss strategies or to increase muscular strength. These training regimens were aerobic training (AT) and circuit resistance training (CT). The postmenopausal women (48 to 60 years of age) were randomly assigned to one of the following exercise training regimens: WBVT, CT or AT. Participants performed their training regimens three times per week for 8 weeks. The training regimens were progressive in nature with increases in training intensity and duration occurring throughout the 8-week period. Body composition and bone mineral density data were obtained by DEXA analyses. Upper and lower body strengths were determined by one repetition maximum (1-RM) chest press and leg press, respectively. A treadmill VO2peak test was performed to assess aerobic capacity. The following statistical analyses were performed: a 3 x 2 repeated measures ANOVA, with three levels of exercise modalities (WBVT, AT, and CT) and two levels of time (pre and post); one-way ANOVA on change scores; and, because sample size was small, non-parametric analyses. There were no significant effects of any of the training modalities for percent body fat, lean body mass, bone mineral density, or VO2peak. The 1-RM for lower body strength increased for all three training modalities. The 1-RM for upper body strength increased for the CT modality. The results indicate that 8 weeks of WBVT is as effective as CT and AT training regimens for increasing lower body strength in post-menopausal women. None of the 8-week training modalities influenced changes in body composition, bone mineral density, or VO2peak. / Kinesiology

Made available in DSpace on 2016-08-19T18:16:03Z (GMT). No. of bitstreams: 1 MARILIA LEAL FERREIRA LAGO.pdf: 216529 bytes, checksum: 435c5f8a55505185c35ba10df038cf6f (MD5) Previous issue date: 2010-11-24 / Objective: Check if there are differences in salivary flow of postmenopausal women with and without estroprogestative and estrogen hormone therapy Methods: We conducted a study of case-control, composed of 86 postmenopausal women, comprising in the case group, 47 users estroprogestative or estrogen HRT, and the control group, 39 women not taking HRT. All patients underwent history taking, through the application of a standard questionnaire, followed by the realization of sialometry stimulated whole. It was used as comparative values, the normal flow from 1.0 to 3.0 mL / min flow down from 0.7 to 1.0 mL / min; hyposalivation, less than 0.7 mL / min. Data were statistically analyzed by chi-square and Student t test (p <0.05). Results: There were no statistically significant differences in the variables analyzed, except for body mass index. Conclusion: In this sample, the flow of saliva in postmenopausal women is not influenced by hormone therapy, regardless of whether estroprogestative or estrogen. / Objetivo: Verificar se existem diferenças no fluxo salivar de mulheres na pós-menopausa com e sem terapia hormonal estroprogestativa e estrogênica. Métodos: Realizou-se um estudo do tipo caso-controle, composto por 86 mulheres na pósmenopausa, contendo, no grupo caso, 47 usuárias de TRH estroprogestativa ou estrogênica, e no grupo controle, 39 mulheres que não utilizavam a TRH. Todas as pacientes foram submetidas à anamnese, por meio da aplicação de um questionário padrão, seguido da realização de sialometria total estimulada e da obtenção do índice de massa corporal. Utilizou-se, como valores comparativos, fluxo normal de 1,0 a 3,0 mL/min, baixo fluxo de 0,7 a 1,0 mL/min; hipossalivação, menos de 0,7 mL/min. Os dados levantados foram submetidos à análise estatística, pelos testes qui-quadrado e t de student (p<0,05). Resultados: Não foram encontradas diferenças estatísticas significativas nas variáveis analisadas, exceto no índice de massa corporal. Conclusão: Na amostra estudada, o fluxo salivar de mulheres na pós-menopausa não sofre influência da terapia hormonal, independente de ser estroprogestativa ou estrogênica.

Introdução: As alterações do assoalho pélvico nas mulheres climatéricas, decorrentes das variações hormonais, de modificações físicas e do próprio envelhecimento dos tecidos, podem ser responsáveis por disfunções urinárias e sexuais. O papel da fisioterapia no tratamento da incontinência urinária tem sido documentado, porém há poucos estudos avaliando a disfunção sexual. Objetivos: Avaliar o potencial de ativação mioelétrica das musculaturas do assoalho pélvico, a função sexual através do Índice de Função Sexual Feminina (IFSF) e a qualidade de vida (Escala de Cervantes) de mulheres climatéricas com e sem dispareunia. Métodos: Estudo transversal realizado no ambulatório de Climatério do Serviço de Ginecologia do Hospital de Clínicas de Porto Alegre (HCPA) com mulheres climatéricas entre 45 e 60 anos. As participantes eram submetidas a uma anamnese e dois questionários (de qualidade de vida - Escala de Cervantes e o Índice de Função Sexual Feminina - IFSF), além da avaliação da musculatura do assoalho pélvico por meio do biofeedback eletromiográfico. Resultados: A amostra foi composta por 51 mulheres com idade média de 52,1 anos (± 4,9). Não houve diferença estatisticamente significativa em relação ao tônus muscular de repouso entre mulheres com e sem dispareunia (p=0,152). Contudo, nas mulheres com dispareunia o IFSF apresentou um pior escore (p<0,001) assim como na escala de Cervantes (p=0,009) em comparação às mulheres sem dispareunia. Houve, também, uma associação inversa significativa entre o escore de dor do FSFI e a média do tônus de base (rs= -0,300; p= 0,033). Conclusão: O presente estudo demonstrou não haver diferença entre o tônus de repouso das musculaturas do assoalho pélvico de mulheres climatéricas com e sem dispareunia. Entretanto houve diferença entre os dois grupos quanto à qualidade de vida (Escala de Cervantes) e função sexual (IFSF). Outros estudos na área da fisioterapia e disfunção sexual são necessários para aprimorar a qualidade de investigação e intervenção de mulheres climatéricas com disfunção sexual. / Introduction. Alterations in the pelvic floor during menopausal years, which are the result of hormonal and physical changes and of tissue aging itself, can lead to urinary and sexual dysfunction. The role of physical therapy in the treatment of urinary incontinence is well documented, but few studies have assessed its role in sexual dysfunction. Aim. To assess the myoelectric action potential of pelvic floor muscles, sexual function (using the Female Sexual Function Index, FSFI) and quality of life (using the Cervantes Scale) in perimenopausal and menopausal women with and without dyspareunia. Methods. Cross-sectional study carried out at the outpatient Menopause clinic of the Department of Gynecology, Hospital de Clínicas de Porto Alegre (HCPA), Brazil, in a sample of climacteric women aged 45 to 60 years. Participants were interviewed, completed two questionnaires (Cervantes Scale and FSFI), and underwent assessment of the pelvic floor muscles by the electromyographic biofeedback method. Results. The sample comprised 51 women with a mean age of 52.1±4.9 years. There were no statistically significant differences in resting muscle tone between women with and without dyspareunia (P = 0.152). However, women with dyspareunia scored worse on the FSFI (P < 0.001) and the Cervantes Scale (P = 0.009) as compared to women without dyspareunia. Furthermore, there was a significant inverse association between FSFI pain scores and mean resting tone (rs = -0.300; P = 0.033). Conclusions. Although myoelectric activation potentials were similar in women with and without dyspareunia, there were between-group differences in FSFI and Cervantes Scale scores. Further studies are required with the possibility of standardize assessment and physical therapy interventions in climacteric women with dyspareunia.

abstract: Background. Despite research aimed at understanding the mechanisms of essential hypertension, instances of this condition continue to rise. Recent findings indicate that the administration of dietary nitrates, in the form of beetroot juice and other nitrate-rich vegetables, may offer anti-hypertensive effects in various study populations. Objective. This randomized, placebo-controlled, crossover trial sought to compare the effects of high-nitrate vegetable salads to the effects of low-nitrate canned vegetables on plasma nitrate/nitrite concentration, peripheral and central-aortic systolic and diastolic blood pressures, pulse wave velocity, and flow-mediated dilation. Methods. Healthy, post-menopausal women (n=5; 80% Caucasian; 52.6 ± 5.7 years) with mildly elevated blood pressure (mean blood pressure ≥ 115/70 mm Hg and < 140/80 mm Hg) were randomly assigned to ingest a fresh, high-nitrate vegetable salad or a low-nitrate vegetable medley, twice per day, for a total of 10 consecutive days. Given the crossover design of the trial, participants observed a two to three week washout period followed by reassignment to the opposite condition. Findings were considered significant at a p-value < 0.05, and Wilcoxon Signed-Rank tests compared mean differences between conditions. Results. Plasma nitrate/nitrite concentration was significantly higher following consumption of the high-nitrate versus the low-nitrate condition (p = 0.043). Conversely, the differences in peripheral systolic and diastolic blood pressures were not statistically significant (p = 0.345 and p = 0.684 for systolic and diastolic pressures, respectively) nor were the differences in central-aortic systolic and diastolic blood pressures statistically significant (p = 0.225 and p = 0.465 for systolic and diastolic pressures, respectively). Similarly, when comparing the effects of the high-nitrate condition to the low-nitrate condition, the difference in pulse wave velocity was not statistically significant (p = 0.465). Finally, flow-mediated dilation tended to improve following consumption of the high nitrate condition (p = 0.080). Conclusion. Twice daily consumption of a fresh, high-nitrate vegetable salad significantly increased plasma nitrate/nitrite concentration. Although the trial was underpowered, there was a trend for improved flow-mediated dilation. Finally, twice daily consumption of a fresh, high-nitrate vegetable salad did not significantly lower peripheral or central-aortic systolic or diastolic blood pressures or pulse wave velocity. / Dissertation/Thesis / Masters Thesis Nutrition 2017

Introdução: As alterações do assoalho pélvico nas mulheres climatéricas, decorrentes das variações hormonais, de modificações físicas e do próprio envelhecimento dos tecidos, podem ser responsáveis por disfunções urinárias e sexuais. O papel da fisioterapia no tratamento da incontinência urinária tem sido documentado, porém há poucos estudos avaliando a disfunção sexual. Objetivos: Avaliar o potencial de ativação mioelétrica das musculaturas do assoalho pélvico, a função sexual através do Índice de Função Sexual Feminina (IFSF) e a qualidade de vida (Escala de Cervantes) de mulheres climatéricas com e sem dispareunia. Métodos: Estudo transversal realizado no ambulatório de Climatério do Serviço de Ginecologia do Hospital de Clínicas de Porto Alegre (HCPA) com mulheres climatéricas entre 45 e 60 anos. As participantes eram submetidas a uma anamnese e dois questionários (de qualidade de vida - Escala de Cervantes e o Índice de Função Sexual Feminina - IFSF), além da avaliação da musculatura do assoalho pélvico por meio do biofeedback eletromiográfico. Resultados: A amostra foi composta por 51 mulheres com idade média de 52,1 anos (± 4,9). Não houve diferença estatisticamente significativa em relação ao tônus muscular de repouso entre mulheres com e sem dispareunia (p=0,152). Contudo, nas mulheres com dispareunia o IFSF apresentou um pior escore (p<0,001) assim como na escala de Cervantes (p=0,009) em comparação às mulheres sem dispareunia. Houve, também, uma associação inversa significativa entre o escore de dor do FSFI e a média do tônus de base (rs= -0,300; p= 0,033). Conclusão: O presente estudo demonstrou não haver diferença entre o tônus de repouso das musculaturas do assoalho pélvico de mulheres climatéricas com e sem dispareunia. Entretanto houve diferença entre os dois grupos quanto à qualidade de vida (Escala de Cervantes) e função sexual (IFSF). Outros estudos na área da fisioterapia e disfunção sexual são necessários para aprimorar a qualidade de investigação e intervenção de mulheres climatéricas com disfunção sexual. / Introduction. Alterations in the pelvic floor during menopausal years, which are the result of hormonal and physical changes and of tissue aging itself, can lead to urinary and sexual dysfunction. The role of physical therapy in the treatment of urinary incontinence is well documented, but few studies have assessed its role in sexual dysfunction. Aim. To assess the myoelectric action potential of pelvic floor muscles, sexual function (using the Female Sexual Function Index, FSFI) and quality of life (using the Cervantes Scale) in perimenopausal and menopausal women with and without dyspareunia. Methods. Cross-sectional study carried out at the outpatient Menopause clinic of the Department of Gynecology, Hospital de Clínicas de Porto Alegre (HCPA), Brazil, in a sample of climacteric women aged 45 to 60 years. Participants were interviewed, completed two questionnaires (Cervantes Scale and FSFI), and underwent assessment of the pelvic floor muscles by the electromyographic biofeedback method. Results. The sample comprised 51 women with a mean age of 52.1±4.9 years. There were no statistically significant differences in resting muscle tone between women with and without dyspareunia (P = 0.152). However, women with dyspareunia scored worse on the FSFI (P < 0.001) and the Cervantes Scale (P = 0.009) as compared to women without dyspareunia. Furthermore, there was a significant inverse association between FSFI pain scores and mean resting tone (rs = -0.300; P = 0.033). Conclusions. Although myoelectric activation potentials were similar in women with and without dyspareunia, there were between-group differences in FSFI and Cervantes Scale scores. Further studies are required with the possibility of standardize assessment and physical therapy interventions in climacteric women with dyspareunia.

Introdução: As alterações do assoalho pélvico nas mulheres climatéricas, decorrentes das variações hormonais, de modificações físicas e do próprio envelhecimento dos tecidos, podem ser responsáveis por disfunções urinárias e sexuais. O papel da fisioterapia no tratamento da incontinência urinária tem sido documentado, porém há poucos estudos avaliando a disfunção sexual. Objetivos: Avaliar o potencial de ativação mioelétrica das musculaturas do assoalho pélvico, a função sexual através do Índice de Função Sexual Feminina (IFSF) e a qualidade de vida (Escala de Cervantes) de mulheres climatéricas com e sem dispareunia. Métodos: Estudo transversal realizado no ambulatório de Climatério do Serviço de Ginecologia do Hospital de Clínicas de Porto Alegre (HCPA) com mulheres climatéricas entre 45 e 60 anos. As participantes eram submetidas a uma anamnese e dois questionários (de qualidade de vida - Escala de Cervantes e o Índice de Função Sexual Feminina - IFSF), além da avaliação da musculatura do assoalho pélvico por meio do biofeedback eletromiográfico. Resultados: A amostra foi composta por 51 mulheres com idade média de 52,1 anos (± 4,9). Não houve diferença estatisticamente significativa em relação ao tônus muscular de repouso entre mulheres com e sem dispareunia (p=0,152). Contudo, nas mulheres com dispareunia o IFSF apresentou um pior escore (p<0,001) assim como na escala de Cervantes (p=0,009) em comparação às mulheres sem dispareunia. Houve, também, uma associação inversa significativa entre o escore de dor do FSFI e a média do tônus de base (rs= -0,300; p= 0,033). Conclusão: O presente estudo demonstrou não haver diferença entre o tônus de repouso das musculaturas do assoalho pélvico de mulheres climatéricas com e sem dispareunia. Entretanto houve diferença entre os dois grupos quanto à qualidade de vida (Escala de Cervantes) e função sexual (IFSF). Outros estudos na área da fisioterapia e disfunção sexual são necessários para aprimorar a qualidade de investigação e intervenção de mulheres climatéricas com disfunção sexual. / Introduction. Alterations in the pelvic floor during menopausal years, which are the result of hormonal and physical changes and of tissue aging itself, can lead to urinary and sexual dysfunction. The role of physical therapy in the treatment of urinary incontinence is well documented, but few studies have assessed its role in sexual dysfunction. Aim. To assess the myoelectric action potential of pelvic floor muscles, sexual function (using the Female Sexual Function Index, FSFI) and quality of life (using the Cervantes Scale) in perimenopausal and menopausal women with and without dyspareunia. Methods. Cross-sectional study carried out at the outpatient Menopause clinic of the Department of Gynecology, Hospital de Clínicas de Porto Alegre (HCPA), Brazil, in a sample of climacteric women aged 45 to 60 years. Participants were interviewed, completed two questionnaires (Cervantes Scale and FSFI), and underwent assessment of the pelvic floor muscles by the electromyographic biofeedback method. Results. The sample comprised 51 women with a mean age of 52.1±4.9 years. There were no statistically significant differences in resting muscle tone between women with and without dyspareunia (P = 0.152). However, women with dyspareunia scored worse on the FSFI (P < 0.001) and the Cervantes Scale (P = 0.009) as compared to women without dyspareunia. Furthermore, there was a significant inverse association between FSFI pain scores and mean resting tone (rs = -0.300; P = 0.033). Conclusions. Although myoelectric activation potentials were similar in women with and without dyspareunia, there were between-group differences in FSFI and Cervantes Scale scores. Further studies are required with the possibility of standardize assessment and physical therapy interventions in climacteric women with dyspareunia.

En Afrique subsaharienne, le fardeau exact du cancer reste largement méconnu et sous étudié. La Gambie et le Mali sont parmi les rares pays d'Afrique à avoir des registres de cancer opérationnels basés sur la population. Les données allant de 1988 à 2006 pour la Gambie et de 1987 à 2009 pour Bamako-Mali, ont été utilisées afin d'analyser les taux d'incidence en fonction de l'âge, du sexe, de l'ethnicité et de caractériser les profils des femmes atteintes de cancers du sein et du foie. Les données ont été arbitrairement divisées en deux sous périodes ; 1988-1997 et 1998-2006 pour la Gambie et 1987-1997, 1998-2009 pour Bamako-Mali. En plus de ceci, une étude cas témoins sur les facteurs de risque associés à la vie reproductive des femmes atteintes de cancer du sein a été réalisée au Mali. Dans ces deux pays, le cancer du sein chez les femmes est caractérisé par une prédominance de cancers pré-ménopausiques. Ces femmes sont pour la plupart multipares et leur âge médian au moment du diagnostic est compris dans la tranche d'âge 40-45 ans. L'étude cas témoins a montré une association significative entre l'âge tardif aux premières règles et une augmentation du risque de développer un cancer du sein chez les femmes préménopausées contre une baisse du risque chez les femmes post-ménopausées (pas significatif). Pour ce qui est du cancer du foie, pendant que l'incidence de ce dernier était relativement stable chez les hommes de la Gambie, elle augmentait chez les femmes de ce même pays. Par contre au Mali, une baisse progressive et homogène dans l'incidence du cancer du foie a été observée au fil des ans et pour les deux sexes. Des études supplémentaires sont nécessaires afin de caractériser le profil biologique du cancer du sein et les facteurs de risque qui y sont associés, mais aussi afin d'évaluer le rôle de l'obésité et de l'exposition à l'aflatoxine B1 dans les tendances observées sur le cancer du foie en Afrique de l'Ouest / In Sub-Saharan Africa, the exact burden of cancer remains largely unknown and understudied. The Gambia and Mali are among the few African countries with operational population-based cancer registries. Data from 1988 to 2006 for the Gambia and from 1987 to 2009 for Bamako-Mali were used to analyze the incidence rates according to age, sex and ethnicity and to characterize the profile of women with breast and liver cancers. The data were arbitrarily divided into two periods, 1988-1997 and 1998-2006 for the Gambia and 1987-1997, 1998-2009 for Bamako- Mali. In addition to this, a case-control study evaluating the risk factors associated with the reproductive life of women with breast cancer was conducted in Mali. In both countries, breast cancer in women is characterized by a predominance of premenopausal cancers. These women are mostly parous with a median age at diagnosis in the age group 40-45 years. The case-control study showed a significant association between late age at menarche and increased risk of developing breast cancer in pre-menopausal women against a decrease in risk among post menopausal women. Concerning liver cancer, while the incidence rate was relatively stable among males in the Gambia, it was increasing among females of this country. In contrary, in Mali, a gradual decline and homogeneous in the incidence of liver cancer was observed over the years and for both sexes. Further studies are needed to characterize the biological profile of breast cancer and risk factors associated with it, but also to assess the role of obesity and exposure to aflatoxin B1 in order to understand the trends observed in liver cancer in West Africa

L’hypothèse de l’hormono-dépendance du mélanome cutané est en débat dans la littérature depuis de nombreuses années. Dans ce contexte, il est essentiel de mieux connaître l’influence potentielle de la prise de traitements hormonaux sur le risque de ce cancer.L’objectif de ce projet de thèse était d’étudier l’influence de la prise de traitements hormonaux (contraceptifs oraux, traitements de l’infertilité, progestatifs pris seuls avant la ménopause et traitements hormonaux de la ménopause) sur le risque de mélanome cutané chez les femmes.Le projet a été conduit principalement à partir de la cohorte prospective E3N (Étude épidémiologique auprès de femmes de l’Éducation nationale) portant sur environ100 000 femmes âgées de 40 à 65 ans à l’inclusion en 1990. L’étude E3N inclut des données détaillées sur le profil pigmentaire, l’exposition solaire et la prise de traitements hormonaux des participantes, ainsi que sur la survenue éventuelle de mélanome cutané, dont les cas ont été confirmés par histologie (761 cas confirmés entre 1990 et 2011). Des données complémentaires sur l’exposition solaire, disponibles pour une fraction de la cohorte E3N, ont également été utilisées. Ces données détaillées sont issues de l’enquête cas-témoin nichée E3N-SunExp menée en 2008. Les analyses ont ensuite été étendues au consortium de cohortes européennes prospectives EPIC (European Prospective Investigation into Cancer and Nutrition), sur près de 334 500 femmes parmi lesquelles 1 734 cas de mélanomes incidents ont été diagnostiqués.Les résultats mettent en évidence des associations modestes entre la prise de traitements hormonaux et le risque de mélanome et ne soutiennent pas l’hypothèse de l’hormono-dépendance de ce cancer. Cependant, ils suggèrent un comportement d’exposition intentionnelle aux UV chez leurs utilisatrices, ce qui ouvre une nouvelle perspective pour les recherches futures dans ce domaine. / The hypothesis of a hormonal dependence of cutaneous melanoma has been debated in the literature over past decades. Within this context, it is critical to increase our knowledge on the influence of exogenous hormone use on the risk of this cancer.The aim of this project was to explore the influence of hormonal treatments (oral contraceptives, fertility drugs, premenopausal use of progestogens, and menopause hormone therapy) on the risk of cutaneous melanoma in women.The project was mainly based on the large E3N (Étude épidémiologique auprès de femmes de l’Éducation Nationale) prospective cohort, which included about 100,000 women aged 40-65 years at inclusion in 1990. The cohort collected data on pigmentary phenotype, sun exposure, hormonal treatment use, and medical data including cutaneous melanomas, which were ascertained through pathology reports (761 incident cases between 1990 and 2011). Additional information on sun exposure, available for a portion of the E3N cohort, was used. These detailed data were collected as part of the E3N-SunExp case-control study launched in 2008.Analyses were extended to the EPIC consortium (European Prospective Investigation into Cancer and Nutrition), which includes about 334 500 women and 1,734 incident melanoma cases.The results arising from this project show modest associations between exogenous hormone use and melanoma risk and suggest no strong direct influence of hormones on melanoma development. However, results suggest intentional UV exposure behaviors in exogenous hormone users, which opens new perspectives for future investigations in this field.

No description available.