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In the diploma thesis called Nursing Care as a Complication Prevention Tool in the Patient Stroke Center, we dealt with various aspects of nursing care in the stroke center. The development of nursing research in the stroke center lags behind the development of rapidly growing medical knowledge. With the development of medical care, nursing care should respond flexibly. The research intent was to get comprehensive information on preventing complications in patients in the stroke center using nursing care. We have investigated the complications that may arise in patients with acute stroke and how they can be affected by nursing care. We have set three goals: to find out what stroke complications can be influenced in the acute phase by nursing care, to identify nursing activities by nurses in stroke centers to prevent complications and to identify obstacles and limits of preventive nursing care in the stroke center. These objectives correspond to five identified research questions. We were interested in the opinions of the staff on the provided nursing care and we also wanted to know the perception of the care provided by the patients themselves. We have tried to identify key nursing care sites, identify weaknesses and possible shortcomings, and have sought to find the basis for possible improvement in care. The qualitative research strategy was chosen to achieve the objectives of the thesis. The technique of data collection was an individual depth semi-structured interview with ten respondents. The interviews were subjected to qualitative analysis using the ATLAS.ti program. By coding, a total of 104 codes have been identified, grouped into 20 categories. We identified 18 complications that can occur with a stroke patient. For all these complications, we have found interventions to be prevented or alleviated. The results also show that nurses working in the stroke center should have specialized education for intensive care rather than college education. Specialized education in neurological issues, which nurses can acquire through post-graduate stroke seminars and exercises, is also suitable. We have identified systemic barriers to nursing care, including lack of material, lack of time and lack of staff. As obstacles on the part of nursing staff we have identified nursing indifference, poor mood, poor collaboration with the patient, hurried care, physical limitations (back pain, fatigue), lack of awareness, knowledge or skills and inadequate teamwork. As obstacles on the part of the patient we have evaluated speech disorders, perception disorder, unconsciousness, faulty adaptation, lack of cooperation, lack of understanding, distrust, negation, aggression, restlessness, disorientation, apathy, depression, overvaluation of own abilities, conflict with the patient's family. During the research, other interesting facts emerged that do not directly relate to the goals and research questions.