The Focus of this study is to present Pro-Active approach and its use in pediatric occupational therapy. The main goal is to find out the effect of the Pro-active approach to neurorehabilitation on function capability of children with spastic quadruparesis form of cerebral palsy. In the first part is presented an overview of the issue of the Pro-active approach, which is made on the basis of a literature search. Nine patients participate in this study. The pro-active approach was applied to all of them. The first case study acted as a pre- research, she had 4 months of therapy with 25 therapies. The other 8 case studies took place for 5-weeks, with occupational therapy 3 times a week. Participants were assessed with the Pediatric Evaluation of Disability Inventory (PEDI), measurement of active and passive range of motion in joints at upper extremity and spasticity. Evaluation of model activities was also included. Comparison of initial and control assessment showed an improvement in all measured score. 6 participants had better score in PEDI. For most participants was the range of active and passive motion increase. The degree of spasticity remained unchanged, but the spasticity angle improved. This study confirms that Pro-active approach has a positive effect on functional capabilities of...