This thesis explores potential use of GPGPU libraries to accelerate k-Wave toolkit's acoustic wave propagation simulation. Firstly, the thesis researches and assesses available high level GPGPU libraries. Afterwards, an insight into k-Wave toolkit's current state of simulation acceleration is provided. Based on that, an approach to enhance currently available code for processors into a heterogeneous application, that is capable of being run on graphics card, is proposed. The outcome of this thesis is an application that can utilize graphics card. If graphics card is unavailable, a fallback into thread and SIMD based acceleration for processor is executed. The product of this thesis is then evaluated based on its performance, maintenance difficulty and usability.