Abstract This study is based on the ecosystem theory exploring the interpersonal relationship of so-called New Female Immigrants¡¦ offspring. The researcher used qualitative ways as the main research approach for the study, generating information. through literature analysis, sociometric method and interviews. The findings and results of the study as follows: 1. The ecosystem provides a full and complete view of the issue, the relationships among microsystem, mesosystem, exosystem and macrosystem are deeply connected to and thus affecting one another. 2. From the microsystem¡¦s point of view, mothers¡¦ and teachers¡¦ attitude has had a great impact on the interpersonal relationships of their offspring. 3. Looking at things from the mesosystem¡¦s perspective, parents and teachers rarely communicate with each other. And due to limitation in language expression, the new female immigrants from the southeastern Asia could not rely on the homework diary as the major source of teacher¡¦s ideas information from, which is the most important communication tool between teachers and parents. Therefore, difficulties in language made it harder for the parents to participate in children¡¦s school lives, and affecting the quality of parent and children interaction. 4. As for exosystem considered, the findings concerning the aspects of ¡§school administration¡¨, ¡§curriculum and instruction¡¨, and ¡§policy¡¨, show that educators and policy makers had been lacking of multicultural thinking, and thus leading to a situation where community resources aren¡¦t efficiently used. 5. Macrosystem implies the existence of ethnocentrism thinking. Discrimination and prejudice from the public did influence the interpersonal relationship and adaptability of new female immigrants and their children. According to the above findings, some suggestions were proposed by the researcher for future measures in education and counseling. Key Words: ecosystem theory, Children of the New Female Immigrants, interpersonal relationship ,case study