Submitted by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2015-01-23T16:14:43Z No. of bitstreams: 5 rafaela.pdf: 1470955 bytes, checksum: eed92eb403aa475a00a1b8d776f95ebc (MD5) license_url: 52 bytes, checksum: 3d480ae6c91e310daba2020f8787d6f9 (MD5) license_text: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) license_rdf: 23898 bytes, checksum: e363e809996cf46ada20da1accfcd9c7 (MD5) license.txt: 2109 bytes, checksum: aa477231e840f304454a16eb85a9235f (MD5) / Approved for entry into archive by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2015-02-10T10:51:15Z (GMT) No. of bitstreams: 5 rafaela.pdf: 1470955 bytes, checksum: eed92eb403aa475a00a1b8d776f95ebc (MD5) license_url: 52 bytes, checksum: 3d480ae6c91e310daba2020f8787d6f9 (MD5) license_text: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) license_rdf: 23898 bytes, checksum: e363e809996cf46ada20da1accfcd9c7 (MD5) license.txt: 2109 bytes, checksum: aa477231e840f304454a16eb85a9235f (MD5) / Made available in DSpace on 2015-02-10T10:51:15Z (GMT). No. of bitstreams: 5 rafaela.pdf: 1470955 bytes, checksum: eed92eb403aa475a00a1b8d776f95ebc (MD5) license_url: 52 bytes, checksum: 3d480ae6c91e310daba2020f8787d6f9 (MD5) license_text: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) license_rdf: 23898 bytes, checksum: e363e809996cf46ada20da1accfcd9c7 (MD5) license.txt: 2109 bytes, checksum: aa477231e840f304454a16eb85a9235f (MD5) Previous issue date: 2014 / O objetivo do presente estudo foi verificar se a aplica??o t?pica de bebidas alco?licas destiladas, cacha?a e u?sque, altera a espessura epitelial da mucosa lingual de hamsters. Ap?s c?lculo amostral, 720 campos microsc?picos foram utilizados para mensura??o da espessura total do epit?lio de l?ngua (camada epitelial mais camada c?rnea). Quarenta hamsters foram divididos em dois grupos experimentais, conforme aplica??o da subst?ncia teste, em grupo 1 (cacha?a 48?gl) e grupo 2 (u?sque 40?gl), ambos avaliados em per?odos experimentais de 13 e 20 semanas. A borda contralateral da l?ngua, que n?o recebeu a subst?ncia teste, foi utilizada como controle. Ap?s eutan?sia, as l?nguas foram dissecadas, fixadas em solu??o de formol 10% e processadas para a obten??o de cortes histol?gicos, que foram corados pela t?cnica de hematoxilina e eosina (HE). Para a an?lise morfom?trica, tr?s l?minas por esp?cime foram avaliadas. A espessura do epit?lio, de ambas as bordas da l?ngua, foi mensurada com aux?lio do Programa Motic Images Plus 2.0 (Motic?). Os dados da an?lise morfom?trica foram avaliados pela estat?stica descritiva e teste de Wilcoxon e teste de Mann-Whitney. No grupo cacha?a, em rela??o ? espessura total do epit?lio, houve diferen?a estat?stica significativa entre a m?dia do lado teste, 61,87 (14,75)?m e a m?dia do lado controle, de 67,20 (9,96)?m (p=0,044). Tamb?m observou-se uma redu??o altamente significativa da espessura das camadas epitelial (p<0,001) e c?rnea (p=0,021). No per?odo de 13 semanas, houve diminui??o estat?stica significativa da espessura das camadas c?rnea (p=0,032) e epitelial (p<0,001), enquanto que, em 20 semanas, somente a camada epitelial apresentou-se significativamente reduzida (p=0,002). No grupo u?sque houve aumento significativo da espessura da camada c?rnea (p=0,015) e epitelial (p=0,012) em 13 semanas. Conclui-se que tipos diferentes de bebidas alco?licas destiladas, com concentra??o alco?lica entre 40?gl e 48?gl, promoveram altera??es morfom?tricas e morfol?gicas diferenciadas. A cacha?a promoveu atrofia epitelial, o que poderia facilitar a penetra??o de sust?ncias ou agentes carcinog?nicos. J? o u?sque promoveu hiperplasia, podendo assim sugerir o in?cio do desenvolvimento de les?es pr?-malignas. / Disserta??o (Mestrado) ? Programa de P?s-Gradua??o em Odontologia, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 2013. / ABSTRACT The aim of this study was to determine whether topical application of distilled spirits, cacha?a and whiskey, alter the epithelial thickness of tongue mucosa of hamsters. After sample size calculation, 720 microscopic fields were used to measure the total thickness of the tongue epithelium (epithelial layer over the stratum corneum). Forty hamsters were divided into two groups, depending on the application of the test substance in group 1 (cacha?a 48?gl) and group 2 (whiskey 40?gl), both evaluated in the experimental periods of 13 and 20 weeks. The contralateral side of the tongue, which has not received the test substance was used as control. After euthanasia, the tongues were dissected, fixed in 10% formalin solution, processed to obtain histological sections and were stained by hematoxylin and eosin (HE). For the morphometric analysis, three slides per specimen were evaluated. The thickness of the epithelium, both edges of the tongue, was measured with the aid of the program Motic Images Plus 2.0 (Motic ?). Data from morphometric analysis were evaluated by descriptive statistics and by Wilcoxon and Mann-Whitney tests. In cacha?a group, regarding the total thickness of the epithelium, there was a statistically significant difference between the average of the test side, 61.87 (14.75) ?m and the average of the control side, 67.20 (9.96) ?m (p=0.044). It was also observed a highly significant reduction in the thickness of the epithelium (p<0.001) and the cornea (p=0.021). At 13 weeks, there was a statistically significant decrease in the thickness of the cornea (p=0.032) and epithelial (p<0.001), whereas at 20 weeks, only the epithelial layer was significantly reduced (p=0.002). In the Whiskey group, there was a significant increase in thickness of the cornea (p=0.015) and epithelial (p=0.012) at 13 weeks. It was conclude that different types of distilled spirits with alcohol concentration between 40 ?gl ?and 48 ?gl, promoted ?morphological and morphometric changes differentiated. Cacha?a promoted epithelial atrophy, which could facilitate the penetration of substances give or carcinogens. The whiskey promoted hyperplasia which suggest the early development of premalignant lesions.

Submitted by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2015-01-23T16:14:43Z No. of bitstreams: 5 anne.pdf: 708252 bytes, checksum: 4181732fe1d95bea52fbf78610b24a96 (MD5) license_url: 52 bytes, checksum: 3d480ae6c91e310daba2020f8787d6f9 (MD5) license_text: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) license_rdf: 23898 bytes, checksum: e363e809996cf46ada20da1accfcd9c7 (MD5) license.txt: 2109 bytes, checksum: aa477231e840f304454a16eb85a9235f (MD5) / Approved for entry into archive by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2015-02-10T11:08:27Z (GMT) No. of bitstreams: 5 anne.pdf: 708252 bytes, checksum: 4181732fe1d95bea52fbf78610b24a96 (MD5) license_url: 52 bytes, checksum: 3d480ae6c91e310daba2020f8787d6f9 (MD5) license_text: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) license_rdf: 23898 bytes, checksum: e363e809996cf46ada20da1accfcd9c7 (MD5) license.txt: 2109 bytes, checksum: aa477231e840f304454a16eb85a9235f (MD5) / Made available in DSpace on 2015-02-10T11:08:27Z (GMT). No. of bitstreams: 5 anne.pdf: 708252 bytes, checksum: 4181732fe1d95bea52fbf78610b24a96 (MD5) license_url: 52 bytes, checksum: 3d480ae6c91e310daba2020f8787d6f9 (MD5) license_text: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) license_rdf: 23898 bytes, checksum: e363e809996cf46ada20da1accfcd9c7 (MD5) license.txt: 2109 bytes, checksum: aa477231e840f304454a16eb85a9235f (MD5) Previous issue date: 2013 / A pesquisa intitulada ?Sa?de Bucal de portadores de HIV-AIDS: influ?ncia de fatores sist?micos e locais no determinante sa?de-doen?a?, foi realizada durante o ano de 2012 em Diamantina, Minas Gerais. O objetivo desta pesquisa foi avaliar as condi??es bucais e sist?micas de portadores HIV/AIDS atendidos pelo Programa Municipal de DST-AIDS de Diamantina, provenientes de 24 munic?pios do Vale do Jequitinhonha. Para isso, foram avaliados 118 pacientes com HIV-AIDS. Foram observadas as condi??es de sa?de bucal e geral dos pacientes, condi??es socioecon?micas, aspectos epidemiol?gicos da infec??o pelo HIV (forma de contamina??o e de diagn?stico), uso de terapia antirretroviral de alta pot?ncia (HAART), contagem de linf?citos T CD4, h?bitos presentes (fumo, ?lcool e outras drogas), bem como o acesso destes pacientes a servi?os de Odontologia. Os resultados revelaram que a maioria dos pacientes pertencia ao g?nero masculino (53,4%), a m?dia de idade encontrada foi de 39,7 anos, a forma de contamina??o de 98,3% dos pacientes foi por via sexual e a renda familiar de 44,9% dos pacientes foi de at? 1 (um) sal?rio m?nimo mensal. Foi observado um alto ?ndice de doen?as e les?es bucais, sendo as mais prevalentes as doen?as periodontais (70,3%), a hiperpigmenta??o da mucosa (52,5%), a queilite angular (32,2%) e ulcera??es aftosas recorrentes (29,7%). A hiperpigmenta??o de mucosa parece ser mais frequente entre pacientes em uso de HAART e em tabagistas. A candidose bucal foi associada com diabetes, anemia, xerostomia, uso de HAART e taxa de CD4 > 500 cel/mm3, enquanto a ulcera??o aftosa recorrente foi associada com tabagismo, etilismo e xerostomia. / ABSTRACT The research entitled "Oral Health of HIV-AIDS patients: influence of local and systemic factors" was held during the year 2012 in Diamantina, Minas Gerais. The aim of this research was to evaluate the oral and systemic conditions of patients with HIV / AIDS attended by Municipal DST-AIDS of Diamantina, from 24 cities of Jequitinhonha Valley. To do this, 118 patients with HIV-AIDS were evaluated. The patients were observed about their conditions of oral and general health, socioeconomic aspects, epidemiological aspects of HIV infection (form of contamination and diagnosis), use of highly active antiretroviral therapy (HAART), CD4 count, customs(smoking, alcohol and other drugs), as well as access of these patients to dental services. The results revealed that most of the patients were males (53.4%), mean age was 39.7 years, the form of contamination of 98.3% of patients was through sex and the family income of 44.9% of patients is a monthly wage like $362,00. There was a high rate of disease and oral lesions, the most prevalent periodontal diseases (70.3%), mucosal hyperpigmentation (52.5%), angular cheilitis (32.2%) and recurrent aphthous ulcerations ( 29.7%). Hyperpigmentation of mucosa seems to be more frequent among patients on HAART and in smokers. Oral candidiasis was associated with diabetes, anemia, xerostomia, HAART use and CD4 count> 500 cells/mm3, while recurrent aphthous ulceration was associated with smoking, alcohol and xerostomia.

Submitted by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2015-02-19T13:03:28Z No. of bitstreams: 5 crisley.pdf: 2081607 bytes, checksum: 90ca0fb9cd507118e713cc82f093637a (MD5) license_url: 52 bytes, checksum: 3d480ae6c91e310daba2020f8787d6f9 (MD5) license_text: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) license_rdf: 23898 bytes, checksum: e363e809996cf46ada20da1accfcd9c7 (MD5) license.txt: 2110 bytes, checksum: b4c884761e4c6c296ab2179d378436d4 (MD5) / Approved for entry into archive by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2015-02-20T09:27:10Z (GMT) No. of bitstreams: 5 crisley.pdf: 2081607 bytes, checksum: 90ca0fb9cd507118e713cc82f093637a (MD5) license_url: 52 bytes, checksum: 3d480ae6c91e310daba2020f8787d6f9 (MD5) license_text: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) license_rdf: 23898 bytes, checksum: e363e809996cf46ada20da1accfcd9c7 (MD5) license.txt: 2110 bytes, checksum: b4c884761e4c6c296ab2179d378436d4 (MD5) / Made available in DSpace on 2015-02-20T09:27:10Z (GMT). No. of bitstreams: 5 crisley.pdf: 2081607 bytes, checksum: 90ca0fb9cd507118e713cc82f093637a (MD5) license_url: 52 bytes, checksum: 3d480ae6c91e310daba2020f8787d6f9 (MD5) license_text: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) license_rdf: 23898 bytes, checksum: e363e809996cf46ada20da1accfcd9c7 (MD5) license.txt: 2110 bytes, checksum: b4c884761e4c6c296ab2179d378436d4 (MD5) Previous issue date: 2013-12-17 / A busca por energias alternativas, sustent?veis e economicamente vi?veis, colocou em destaque o uso dos biocombust?veis. Os estudos recentes apontam o uso de biomassas residuais como candidatas potenciais para produ??o de bioenergia. Nesse contexto, a presente disserta??o teve por objetivo ava-liar a torta de dend? como insumo para produ??o de etanol de segunda gera??o por meio de estudos que envolveram etapas de pr?-tratamento ?cido e alcalino, sacarifica??o e fermenta??o. Inicialmente foi determinada a composi??o centesimal da torta de dend?, indicando a presen?a de 53,2% de car-boidratos totais, dos quais 32% referente a fra??o de celulose. Para otimiza??o do pr?-tratamento ?cido foi aplicado um Planejamento Fatorial atrav?s de delineamento composto central rotacional. O programa STATISTICA Vers?o 8.0 (Statsoft Inc., Tulsa,) foi utilizado para an?lise dos dados. O pr?-tratamento com ?cido sulf?rico dilu?do resultou na remo??o de pelo menos 82% da hemicelulose presente na torta de dend?. O pr?-tratamento alcalino subsequente foi capaz de remover pelo menos 72% da lignina da biomassa, um interferente do processo fermentativo. Na sequ?ncia o processo de sacarifica??o foi otimizado com o uso de delineamento composto central rotacional com 3 fatores, 4 pontos centrais e 6 pontos axiais, onde foram avaliadas a concentra??o de celulases, a raz?o s?lido-l?quido e o tempo. O hidrolisado enzim?tico obtido em condi??o otimizada, com 80% de convers?o da celulose a a??cares redutores, foi submetido ? fermenta??o com Saccharomyces cerevisiae apre-sentando um YP/S de 0,49 com 5,4%(v/v) de ?lcool no mosto fermentado. Os dados obtidos indicaram que a torta de dend? avaliada apresenta elevado potencial para produ??o de bioetanol de segunda gera??o. / Disserta??o (Mestrado) ? Programa de P?s-Gradua??o em Qu?mica, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 2013. / ABSTRACT The search for alternative energies, sustainable and economically viable, highlighted the use of biofuels. Recent studies indicate the use of residual biomass as potential candidates for bioenergy production. In this context, the present dissertation aimed at evaluating the palm cake as a feedstock for the production of second generation ethanol through studies involving acid and alkaline pretreatment steps, saccharification and fermentation. Initially it was determined the chemical composition of palm cake, indicating the presence of 53.2% of total carbohydrates, of which 32% related to cellulose. To optimize the pretreatment was applied a Factorial Design by central composite rotational design. The program STATISTICA version 8.0 (Statsoft Inc., Tulsa,) was used for data analysis. Pretreatment with dilute sulfuric acid resulted in the removal of at least 82% of the hemicellulose present in palm cake. The subsequent alkaline pretreatment was able to remove at least 72% of the lignin from the biomass, an interfering of fermentation. Further the saccharification process was optimized by the use of central composite design with three factors, fourth central points and six axial points, evaluating the concentration of cellulase, the solid-liquid ratio and the time. The enzymatic hydrolyzate obtained under optimized conditions with 80% conversion of cellulose to sugars was subjected to fermentation with Saccharomyces cerevisiae showing an YP/S of 0.49 based on 5.4% (v/v) of alcohol in the fermented must. The data indicated that the palm kernel cake evaluated presents high potential for production of second generation bioethanol.

Submitted by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2015-02-19T13:34:45Z No. of bitstreams: 5 fab.pdf: 3600092 bytes, checksum: 62e73afe3033394e17b7ea0fbf24fbf8 (MD5) license_url: 52 bytes, checksum: 3d480ae6c91e310daba2020f8787d6f9 (MD5) license_text: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) license_rdf: 23898 bytes, checksum: e363e809996cf46ada20da1accfcd9c7 (MD5) license.txt: 2110 bytes, checksum: b4c884761e4c6c296ab2179d378436d4 (MD5) / Approved for entry into archive by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2015-02-20T10:44:39Z (GMT) No. of bitstreams: 5 fab.pdf: 3600092 bytes, checksum: 62e73afe3033394e17b7ea0fbf24fbf8 (MD5) license_url: 52 bytes, checksum: 3d480ae6c91e310daba2020f8787d6f9 (MD5) license_text: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) license_rdf: 23898 bytes, checksum: e363e809996cf46ada20da1accfcd9c7 (MD5) license.txt: 2110 bytes, checksum: b4c884761e4c6c296ab2179d378436d4 (MD5) / Made available in DSpace on 2015-02-20T10:44:39Z (GMT). No. of bitstreams: 5 fab.pdf: 3600092 bytes, checksum: 62e73afe3033394e17b7ea0fbf24fbf8 (MD5) license_url: 52 bytes, checksum: 3d480ae6c91e310daba2020f8787d6f9 (MD5) license_text: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) license_rdf: 23898 bytes, checksum: e363e809996cf46ada20da1accfcd9c7 (MD5) license.txt: 2110 bytes, checksum: b4c884761e4c6c296ab2179d378436d4 (MD5) Previous issue date: 2013-02-20 / Eletrodos perme?veis a fluidos (EPF) foram confeccionados mediante a eletrodeposi??o do di?xido de chumbo (PbO2) sobre substratos constitu?dos de tecido de carbono (TC) do tipo sarja empregando-se diferentes condi??es experimentais. Foi investigada a influ?ncia dos diferentes tipos de pr?-tratamento do TC na eletross?ntese dos filmes de PbO2. Os substratos pr?-tratados foram caracterizados empregando-se a t?cnica de voltametria c?clica (VC), enquanto que os filmes de PbO2 suportados sobre o TC pr?-tratado foram caracterizados pelas t?cnicas de difratometria de raios-X (DRX), microscopia ?tica (MO), microscopia eletr?nica de varredura (MEV), e a voltametria. Foi verificado que o pr?-tratamento do TC empegando-se o isopropanol ? o mais apropriado para a eletross?ntese dos filmes de PbO2 visando a obten??o de um EPF. O estudo de caracteriza??o ?ex-situ? (DRX, MO e MEV) revelou que as condi??es experimentais mais satisfat?rias para a forma??o da fase ?-PbO2 sobre o TC pr?-tratado, de modo a se obter um EPF, s?o: pH ? 2; 40 oC ? T < 70 oC, e 40 mA cm-2. O comportamento eletroqu?mico do EPF (TC/?-PbO2) foi investigado na condi??o de ?zero-gap? empregando-se a membrana Nafion? 117 (DuPont) como eletr?lito s?lido e a ?gua destilada como fase l?quida. A an?lise das curvas de polariza??o registradas em condi??es quase-estacion?rias para o processo eletr?dico misto da rea??o de desprendimento de oxig?nio (RDO) acompanhada pela rea??o de forma??o de oz?nio (RFO) revelou a presen?a de duas inclina??es de Tafel distribu?das nos dom?nios dos baixos e dos altos sobrepotenciais. Foi obtido um valor de 16 kJ mol-1 para a entalpia de ativa??o aparente determinada no dom?nio dos elevados sobrepotenciais. O estudo envolvendo a quantifica??o do oz?nio produzido com o anodo do tipo TC/?-PbO2 empregando-se um prot?tipo de reator do tipo filtro-prensa revelou que este tipo de EPF n?o ? adequado para o processo da produ??o eletroqu?mica de oz?nio. Entretanto, a grande estabilidade qu?mica e mec?nica apresentada pelo TC/?-PbO2 aliada ao seu grande sobrepotencial para o processo da RDO permite inferir que reatores do tipo filtro-prensa empregando-se este tipo de anodo s?o bastante promissores para processos de interesse ambiental envolvendo a combust?o de poluentes org?nicos presentes em ?guas. / Disserta??o (Mestrado) ? Programa de P?s-Gradua??o em Qu?mica, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 2011. / ABSTRACT Electrodes permeable to fluids (EPF) were fabricated by electrodeposition of lead dioxide (PbO2) on substrates made of twill type woven carbon (TC) using different experimental conditions. There has been investigated the influence of the different types of pre-treatment on TC in the electrosynthesis of PbO2 films. The pretreated substrates were characterized using the technique of cyclic voltammetry (VC), while the PbO2 films supported on pre-treated TC were characterized by the techniques of X-ray diffraction (DRX), optical microscopy (MO), scanning electron microscopy (MEV) and voltammetry. It was observed that the pre-treatment of TC using isopropanol is the most suitable electrosynthesis of PbO2 films for obtaining an EPF. The characterization study "ex-situ" (DRX, MO e MEV)) revealed that the experimental conditions more suitable for the formation of phase ?-PbO2 on the TC pre-treated in order to obtain an EPF, are pH ? 2; 40 oC ? T < 70 oC, e 40 mA cm-2. The electrochemical behavior of EPF (TC/?-PbO2) was investigated in the condition of "zero-gap" employing the Nafion? 117 membrane (DuPont) as solid electrolyte and distilled water as the liquid phase. The analysis of polarization curves recorded in quasi-stationary conditions for the mix electrode process of from the mixture of oxygen detachment reaction (RDO) accompanied by the reaction of ozone formation (RFO) has revealed the presence of two Tafel slopes distributed in the areas of low and high overpotentials. There was obtained a value of 16 kJ mol-1 for the apparent activation enthalpy determined in the field of high overpotentials. The study involving the measurement of ozone produced in the anode-type TC/?-PbO2 employing a prototype reactor of the filter-press revealed that this type of EPF is not suitable for the process of electrochemical production of ozone. However, the high chemical and mechanical stability provided by the TC/?-PbO2 combined with its large overpotential for the process of RDO allows to infer that reactors of filter-press employing this type of anode are very promising for processes of environmental interest involving the combustion of organic pollutants in waste water.

Submitted by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2015-02-27T13:30:29Z No. of bitstreams: 5 1.pdf: 759671 bytes, checksum: 1f3560e9506658bab885766f9f65fd21 (MD5) license_url: 49 bytes, checksum: fd26723f8d7edacdb29e3f03465c3b03 (MD5) license_text: 20626 bytes, checksum: 7851d446050a985bd0603b7c4cee472d (MD5) license_rdf: 19710 bytes, checksum: aa65da15f424ff71c620a992a187295c (MD5) license.txt: 2109 bytes, checksum: aa477231e840f304454a16eb85a9235f (MD5) / Approved for entry into archive by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2015-02-27T14:09:52Z (GMT) No. of bitstreams: 5 1.pdf: 759671 bytes, checksum: 1f3560e9506658bab885766f9f65fd21 (MD5) license_url: 49 bytes, checksum: fd26723f8d7edacdb29e3f03465c3b03 (MD5) license_text: 20626 bytes, checksum: 7851d446050a985bd0603b7c4cee472d (MD5) license_rdf: 19710 bytes, checksum: aa65da15f424ff71c620a992a187295c (MD5) license.txt: 2109 bytes, checksum: aa477231e840f304454a16eb85a9235f (MD5) / Made available in DSpace on 2015-02-27T14:09:52Z (GMT). No. of bitstreams: 5 1.pdf: 759671 bytes, checksum: 1f3560e9506658bab885766f9f65fd21 (MD5) license_url: 49 bytes, checksum: fd26723f8d7edacdb29e3f03465c3b03 (MD5) license_text: 20626 bytes, checksum: 7851d446050a985bd0603b7c4cee472d (MD5) license_rdf: 19710 bytes, checksum: aa65da15f424ff71c620a992a187295c (MD5) license.txt: 2109 bytes, checksum: aa477231e840f304454a16eb85a9235f (MD5) Previous issue date: 2010 / Objetivou-se com este trabalho avaliar os efeitos de diferentes aduba??es de solo e doses de N em cobertura na cultura da alface. O experimento foi realizado no campus JK da UFVJM, em Diamantina/MG, no per?odo compreendido entre junho e setembro de 2008. O delineamento experimental utilizado foi em blocos ao acaso com parcelas subdivididas, com tr?s blocos, cinco aduba??es de solo: NPK+esterco, NPK, esterco, composto org?nico e vermicomposto e cinco doses de N em cobertura, sendo a parcela experimental constitu?da por dezesseis plantas, espa?adas em 0,30 m x 0,30 m. Foram avaliados a massa seca e fresca da parte a?rea, di?metro da cabe?a, n?mero de folhas, altura de plantas, vari?vel can?nica e teores foliares de N, P, K, Ca, MG, S, B, Cu, Fe, Mn e Zn. As vari?veis de produ??o foram afetadas pelo tipo de aduba??o de solo e pelas doses de N aplicadas em cobertura. A aduba??o com esterco foi a que proporcionou os melhores resultados para as caracter?sticas de produ??o avaliadas, seguida das aduba??es com NPK+esterco e vermicomposto. Para o cultivo da alface na regi?o de Diamantina/MG, recomenda-se aplicar 160 kg.ha-1 de N em cobertura. O processo de vermicompostagem reduziu os teores de B, Cu, Fe e Mn na parte a?rea das plantas de alface. Os teores dos nutrientes nas plantas de alface variaram em fun??o da aduba??o de solo e das doses de nitrog?nio em cobertura, o que mostra que, com o aumento das doses de N, houve aumento nos teores foliares dos nutrientes analisados, exceto para o B, Cu e Zn. / Disserta??o (Mestrado) ? Programa de P?s-Gradua??o em Produ??o Vegetal, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 2009. / ABSTRACT The objective of this study was to evaluate the effects of different soil fertilization and nitrogen rates in coverage on lettuce cultivation. The experiment was accomplished on JK campus of UFVJM, Diamantina/MG, in the period between June and September of 2008. The experimental design was a randomized block with split plot with three blocks and five fertilization of soil: NPK + manure, fertilizer, manure, organic compost, vermicompost and five doses of nitrogen in coverage, considering that the experimental plot was composed of sixteen plants spaced by 0.30 m x 0.30 m. The dry and fresh weight, head diameter, leaf number, plant height, canonical variable and foliar contents of N, P, K, Ca, Mg, S, B, Cu, Fe, Mn and Zn were evaluated. The growth variables were affected by the type of soil fertilization and N rates applied in coverage. The manuring was the one that provided the best results for the evaluated growth features, followed by fertilization with NPK+manure and vermicompost. For the lettuce cultivation in the region of Diamantina/MG, it is recommended to apply 160 kg.ha-1 N in coverage. The vermicomposting process reduced the B, Cu, Fe and Mn content in lettuce weights. The nutrient contents in lettuce plants varied according to soil fertilization and nitrogen dosage in coverage, which shows that with increasing doses of N, there was an increase in the analyzed foliar nutrients, except for the B, Cu and Zn.

Submitted by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2016-01-05T13:42:22Z No. of bitstreams: 2 uidemar_morais_barral.pdf: 1274629 bytes, checksum: d89bbca6115310a0b5ad8323167ba551 (MD5) license_rdf: 22974 bytes, checksum: 99c771d9f0b9c46790009b9874d49253 (MD5) / Approved for entry into archive by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2016-01-05T18:01:03Z (GMT) No. of bitstreams: 2 uidemar_morais_barral.pdf: 1274629 bytes, checksum: d89bbca6115310a0b5ad8323167ba551 (MD5) license_rdf: 22974 bytes, checksum: 99c771d9f0b9c46790009b9874d49253 (MD5) / Made available in DSpace on 2016-01-05T18:01:03Z (GMT). No. of bitstreams: 2 uidemar_morais_barral.pdf: 1274629 bytes, checksum: d89bbca6115310a0b5ad8323167ba551 (MD5) license_rdf: 22974 bytes, checksum: 99c771d9f0b9c46790009b9874d49253 (MD5) Previous issue date: 2015 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior (Capes) / A mat?ria org?nica (MOS) do solo consiste de uma mistura de compostos em v?rios est?gios de decomposi??o, resultante da degrada??o biol?gica de res?duos de plantas e animais, e da atividade de microrganismos, denominados subst?ncias h?micas (SHs). Essas subst?ncias fracionadas em ?cidos f?lvicos (AF), ?cidos h?micos (AH) e humina (H), de acordo com sua solubilidade em meio ?cido ou b?sico. Os AH t?m sido usados como fertilizantes aplicados diretamente no solo ou via foliar, principalmente por influenciarem o metabolismo das plantas. Objetivou-se com este trabalho avaliar em feijoeiro (Phaseolus vulgaris L.), a influ?ncia de fontes e doses diferentes de AH, na produ??o, crescimento radicular e absor??o de nutrientes e biodisponibilidade de nutrientes no solo. O experimento foi conduzido utilizando o delineamento em blocos casualizados com 15 tratamentos, sendo estes as fontes de AH (turfa - 1, composto - 2 e produto comercial - 3) e as doses de AH (0, 2, 8, 16 e 32 kg ha-1), com quatro repeti??es. Foram avaliadas: altura das plantas (cm), di?metro do caule (cm), teor de clorofila (?g cm-2) e teor de macro e micronutrientes nas folhas no florescimento do feijoeiro e ao fim do experimento, peso de sementes (g), massa seca da parte a?rea e de ra?zes (g), n?mero de vagem por planta e de sementes por vagem e no solo: pH em ?gua e teores de mat?ria org?nica, P, K, Ca, Mg, Al e H+Al. A aplica??o de AH reduziu o crescimento e produ??o de gr?o, com aumento das doses em cada fonte, seguindo a ordem fonte 3 > fonte 1 > fonte 2. Os teores de P, K, Cu, Fe, Mn e Zn nas folhas foram influenciados pelas doses de todas as fontes de AH. Houve redu??o para maioria dos nutrientes quantificados nas folhas com aumento das doses de AH. Os teores de P e K se elevaram no solo, com a aplica??o de AH. Para condi??es testadas, n?o se recomenda utiliza??o de AH para cultura do feijoeiro. / Disserta??o (Mestrado) ? Programa de P?s-Gradua??o em Produ??o Vegetal, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 2015. / ABSTRACT The soil organic matter (SOM) consists of a mixture of compounds in many decomposition stages, the result of biological degradation of residues of plants and animals, and microorganisms activity, called humic substances (HS). These substances are fractionated into fulvic acids (FA), humic acids (HA) and humin (H), according to their solubility in acidic or basic medium. HA have been used as fertilizers directly applied to the soil or via foliar, mainly because they influence plants metabolism. The main goal of this study was evaluating, in bean plant (Phaseolus vulgaris L.), the influence of sources and different doses of HA in production, root growth, nutrients absorption and bioavailability of nutrients in the soil. The experiment was conducted using randomized block design with 15 treatments, which are the sources of HA (peat ? 1, compound ? 2 and commercial product ? 3) and doses of HA (0, 2, 8, 16 e 32 kg ha-1), with four repetitions. Evaluations were made on: plants height (cm), stem diameter (cm), chlorophyll content (?g cm-2) and content of macro and micronutrients in the leaves in the flowering stages and in the end of the experiment, seeds weight (g), dry matter of the aerial part and roots (g), number of pods per plant and seeds per pod, and in the soil: pH in water and contents of organic matter, P, K, Ca, Mg, Al and H+Al. Application of HA reduced bean growth and production, with increase of doses in each source, following order: source 3 > source 1 > source 2. Contents of P, K, Cu, Fe, Mn and Zn in the leaves were influenced by the doses of all HA sources. Most of the nutrients quantified in the leaves were reduced with increasing HA doses. Contents of P and K were increased in the soil with application of HA. For tested conditions, the use of HA for bean culture is not recommended.

Submitted by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2016-01-12T17:40:07Z No. of bitstreams: 2 license_rdf: 22974 bytes, checksum: 99c771d9f0b9c46790009b9874d49253 (MD5) lucio_flavio_macedo_mota.pdf: 1719975 bytes, checksum: 3893bff470fc397394ef7bd5048cfde3 (MD5) / Approved for entry into archive by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2016-01-12T17:40:32Z (GMT) No. of bitstreams: 2 license_rdf: 22974 bytes, checksum: 99c771d9f0b9c46790009b9874d49253 (MD5) lucio_flavio_macedo_mota.pdf: 1719975 bytes, checksum: 3893bff470fc397394ef7bd5048cfde3 (MD5) / Made available in DSpace on 2016-01-12T17:40:32Z (GMT). No. of bitstreams: 2 license_rdf: 22974 bytes, checksum: 99c771d9f0b9c46790009b9874d49253 (MD5) lucio_flavio_macedo_mota.pdf: 1719975 bytes, checksum: 3893bff470fc397394ef7bd5048cfde3 (MD5) Previous issue date: 2014 / Funda??o de Amparo ? Pesquisa do estado de S?o Paulo (FAPESP) / Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico (CNPq) / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior (CAPES) / Objetivou-se avaliar a influ?ncia da express?o da leptina e relacionar as concentra??es de leptina plasm?tica com as caracter?sticas de desenvolvimento corporal, mudan?as no proteoma do m?sculo Longissumus dorsi e o impacto o modelo na estima??o de equa??es de predi??o de consumo de alimentos em bovinos Nelore e no ranking de desempenho alimentar, utilizando diferentes modelos para a estimativa do consumo alimentar residual (CAR). Foi utilizado um total de 97 animais classificados para alto e baixo CAR, medidos para caracter?sticas de ingest?o, crescimento, efici?ncia alimentar, concentra??o plasm?tica de leptina e caracter?sticas de carca?a. Foram abatidos 20 animais classificados para alto e baixo CAR e coletadas amostras do m?sculo Longissimus dorsi, para an?lise da express?o do gene leptina e prote?mica. Os modelos utilizados para estima??o do CAR foram o modelo atualmente em uso e modelos que inclu?ram medidas de ultrassom de m?sculo e espessura de gordura. As amostras de prote?nas extra?das do m?sculo Longissimus dorsi foram separadas em duas etapas: a primeira etapa de separa??o das prote?nas foi realizada por migra??o eletrofor?tica em tira de IPG (Immobilized pH Gel) at? o ponto isoel?trico; a segunda, realizada pela migra??o eletrofor?tica das prote?nas focalizadas na tira de IPG (primeira dimens?o) e em seguida, em gel de acrilamida de acordo com o peso molecular (segunda dimens?o). Ap?s as an?lises dos g?is 2-D, os spots diferencialmente expressos nos grupos de CAR foram excisados para an?lise por dessor??o a laser, assistida por matriz MALDI TOF/TOF. As an?lises estat?sticas foram realizadas utilizando o procedimento MIXED do SAS, as estimativas de correla??o fenot?pica, utilizando o procedimento CORR e a compara??o dos valores de express?o entre as classes de CAR,utilizando o procedimentoCONTRAST do procedimento MIXED. Animais classificados para baixo CAR apresentaram maior express?o do gene leptina (2,80) e maior concentra??o plasm?tica (11,48) deste gene em bovinos Nelore. Os n?veis mais elevados de leptina podem estar envolvidos na redu??o da ingest?o de alimentos em animais classificados para baixo CAR, indicando ser um regulador na diferen?a de consumo de alimentos pelos animais. Embora os modelos de CAR tenham apresentado diferen?as na estima??o, as correla??es entre cada um dos modelos indicaram que estes n?o foram diferentes uns dos outros na classifica??o dos animais para efici?ncia alimentar. A maior express?o de fibras de contra??o lenta em bovinos mais eficientes ocorre devido a uma redu??o preferencial das fibras musculares de contra??o r?pida, como uma adapta??o para melhor lidar com a redu??o da exig?ncia nutricional, por apresentar diferen?as no perfil metab?lico da contra??o muscular. No entanto, a varia??o na efici?ncia do modelo que inclui os par?metros de composi??o corporal ? muito importante, sugerindo que a composi??o corporal pode ser fundamental para explicar a varia??o no consumo de alimentos e que ele precisa ser inclu?do no modelo de c?lculo do CAR. / Disserta??o (Mestrado) ? Programa de P?s-Gradua??o em Zootecnia, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 2014. / ABSTRACT The objectives were to evaluate the effects of leptin expression and to correlate plasma leptin concentrations with corporal development traits, changes in proteomics of the Longissumus dorsi muscle, and the impact of the model approach in estimating predicting equations for feed intake in Nellore animals and in feed performance ranking using different models for the estimation of residual feed intake (RFI). A total of 97 animals, classified for high and low RFI, measured for intake, growth, feed efficiency, plasma leptin concentration, and carcass traits, was utilized. Twenty animals classified for high and low RFI were slaughtered, and Longissimus dorsi muscle was sampled to analyze leptin gene expression and proteomics. Models utilized for RFI estimation were the current model used, and models which included muscle ultrasound and fat thickness measurement. Protein samples of Longissimus dorsi muscle were separated into two stages: the first stage of proteins separation was performed by electrophoretic migration in IPG (Immobilized pH Gel) strip until the isoelectric point; the second, performed by electrophoretic migration of the proteins in the focused IPG strip (first dimension) and then, in acrylamide gel according to the molecular weight (second dimension). After analysis of 2-D gels, spots differentially expressed in RFI groups were excised for analysis by laser desorption assisted by MALDI TOF / TOF matrix. Statistical analyzes were achieved by using the MIXED procedure of SAS, estimation of phenotypic correlation, using the CORR procedure, and comparison of expression values ??among RFI classes, using the CONTRAST procedure of the MIXED procedure. Low RFI animals had greater expression of leptin gene (2.80) and greater plasma concentration (11.48) in Nellore animals. Greater levels of leptin can be involved in the reduction of feed intake in low RFI animals, indicating to be a regulator on feed intake. Although RFI models were different in estimating values, correlations among each model indicate that they were not different in classifying animals for feed efficiency. The greater expression of slow-twitch fibers in more efficient cattle is due to preferential reduction of the fast twitch muscle fibers, as an adaptation to better deal with reduced nutritional requirement because it shows differences in the metabolic profile of muscle contraction. Nonetheless, variation in efficiency of the model that includes body composition parameters is important, suggesting that body composition can be critical to explain variations in feed intake and it must be included in the RFI model.

Submitted by Jos? Henrique Henrique (jose.neves@ufvjm.edu.br) on 2017-07-27T20:49:30Z No. of bitstreams: 2 karen_marina_alves_diniz.pdf: 2490788 bytes, checksum: f57f33837519e4bf59beffaaa5eae22a (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) / Made available in DSpace on 2017-07-28T17:07:39Z (GMT). No. of bitstreams: 2 karen_marina_alves_diniz.pdf: 2490788 bytes, checksum: f57f33837519e4bf59beffaaa5eae22a (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Previous issue date: 2017 / A abdu??o do joelho durante atividades din?micas realizadas em cadeia cin?tica fechada ? considerada o principal mecanismo envolvido nas les?es n?o traum?ticas do joelho. A abdu??o do joelho est? relacionada ao aumento da adu??o do quadril, da rota??o medial do f?mur e da prona??o do p?, tais altera??es cinem?ticas podem ser influenciadas por altera??es de alinhamento estrutural, amplitude de movimento e for?a muscular. Especificamente, o varismo excessivo do antep?, a diminui??o da for?a muscular de rotadores laterais de quadril e o aumento da amplitude de movimento passiva de rota??o medial do quadril podem contribuir para o aumento da prona??o do p? e da rota??o medial da t?bia e f?mur, o que consequentemente pode contribuir para a abdu??o do joelho em cadeia fechada. Portanto, entender como estes fatores em conjunto interagem e influenciam a abdu??o do joelho permite desenvolvimento de estrat?gias de preven??o e reabilita??o mais eficientes. O objetivo da presente disserta??o foi investigar a influ?ncia do alinhamento do p?, torque muscular de rotadores laterais do quadril e amplitude de movimento passiva em rota??o medial do quadril na cinem?tica do joelho no plano frontal durante o agachamento unipodal. Quarenta e um indiv?duos participaram do estudo, sendo avaliados nos testes de torque isom?trico de rotadores laterais do quadril (TRLQ), amplitude de movimento (ADM) passiva de rota??o medial (RM) do quadril, alinhamento perna-antep? (APA) e avalia??o da cinem?tica do joelho no plano frontal durante o agachamento unipodal atrav?s do sistema de an?lise do movimento em 3D. A ?rvore de classifica??o e regress?o (Classification and Regression Tree - CART) foi utilizada para identificar os fatores e intera??es que est?o associados ao movimento do joelho no plano frontal. A curva receiver operating characteristic (ROC) foi usada para determinar a acur?cia do modelo desenvolvido pela CART. Finalmente, utilizou-se a raz?o de preval?ncia (RP) para identificar a for?a de associa??o das intera??es indicadas em cada nodo terminal da ?rvore com o desfecho. Os resultados revelaram que 14 indiv?duos (93,3%) classificados com abdu??o do joelho apresentaram menores valores de TRLQ (entre 0,26 e 0,47) e maiores valores de APA (>10,11?), com RP igual a 3,03. O modelo desenvolvido pela CART obteve acur?cia adequada (91,5% (IC 95%= 82,7-100) p < 0.0001), indicando como predi??o correta 81,8% de indiv?duos com abdu??o de joelho e 94,7% de indiv?duos com adu??o do joelho. Concluise que a abdu??o do joelho ? influenciada e depende da intera??o entre TRLQ e APA, sendo assim, indiv?duos com menores valores de TRLQ e maiores APA apresentam abdu??o do joelho. / Disserta??o (Mestrado) ? Programa de P?s-Gradua??o em Reabilita??o e Desempenho Funcional, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 2016. / The knee abduction during dynamic activities in closed kinetic chain is considered the main mechanism involved in non-traumatic knee injuries. Knee abduction is related to the increase in hip adduction, femur medial rotation and foot pronation. These kinematic changes can be influenced by modifications on structural alignment, range of motion and muscular strength. Specifically, the excess of forefoot varus, reduction strength of in the lateral hip rotators and increased passive hip medial rotation can contribute to a higher degree of foot pronation and medial rotation of tibia and femur, which may contribute to the abduction of the closed-chain knee. Therefore the understanding of how these factors interact to influence the keen abduction permits the development of prevention strategies and a more efficient rehabilitation. The aim of the study was to investigate the influence of foot alignment, hip lateral rotator torque and passive hip medial rotator range of motion on frontal plane knee kinematic during single leg squat. Forty one subjects participated in this study. They were tested on the hip lateral rotator isometric torque test (HLIT), passive range of motion (ROM) of hip medial rotator (MR), shank-forefoot alignment (SFA) and were assessed on the frontal plane knee kinematics during single leg squat using a 3D movement analysis system. The Classification and Regression Tree ? CART was used to identify factors and interaction that are associated to the occurrence of knee abduction. The receiver operation characteristic curve (ROC) was used to calculate the accuracy of the model developed by the CART. Finally, prevalence ratio (PR) was used to identify the strength of the association of the interactions indicated at each terminal node with the outcome. The results revealed that 14 subjects (93.3%) classified with knee abduction present lower HLIT values (between 0.26 and 0.47) and higher SFA values (>10.11?, PR=3.03). The model developed by CART had an adequate accuracy (91.5% (IC 95%= 82.7-100) p < 0.0001), indicating a correct prediction of 81.8% of the subjects with knee abduction and 94.7% of the subjects with knee adduction. In conclusion the knee abduction is influenced and depends on the interaction between HLIT and SFA. Subjects with a lower HLIT and higher FSA present knee abduction.

Submitted by Jos? Henrique Henrique (jose.neves@ufvjm.edu.br) on 2018-10-29T17:31:07Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) douglas_novaes_bonifacio.pdf: 1344470 bytes, checksum: 3296da1067a3fd71e852bfafb7cbef48 (MD5) / Approved for entry into archive by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2018-11-10T11:39:14Z (GMT) No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) douglas_novaes_bonifacio.pdf: 1344470 bytes, checksum: 3296da1067a3fd71e852bfafb7cbef48 (MD5) / Made available in DSpace on 2018-11-10T11:39:14Z (GMT). No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) douglas_novaes_bonifacio.pdf: 1344470 bytes, checksum: 3296da1067a3fd71e852bfafb7cbef48 (MD5) Previous issue date: 2018 / Diariamente, o sistema locomotor humano ? desafiado a transpor diferentes n?veis de terrenos. Subir e descer escadas ? uma atividade comum da vida di?ria, podendo ser um obst?culo quando a fun??o motora est? comprometida. Pacientes com dor patelofemoral se queixam de dor retropatelar agravada por atividades como subida e descida de degraus, sendo a dor maior durante a descida de degraus. A necessidade de controle durante a tarefa de descida de degrau e conseguida atrav?s da contra??o muscular exc?ntrica. Na descida de degrau, os indiv?duos devem transportar ativamente o centro de gravidade para frente e resistir a gravidade durante a fase de descida controlada. Estudos v?m investigando respostas das altera??es dos padr?es fisiol?gicos de movimentos nos p?s, por acreditarem que essas altera??es podem originar compensa??es aos membros inferiores. A prona??o excessiva tem sido relacionada a numerosas altera??es funcionais nos membros inferiores, indicando les?es de uso excessivos que afetam o quadril, joelho, tornozelo e p?. Os cl?nicos geralmente concordam que algumas formas de ?rteses ou cal?ados ortop?dicos especializados podem controlar a prona??o excessiva. Diante disso, o presente estudo tem como objetivo avaliar o efeito de uma palminha com cunha medial a cinem?tica, cin?tica e a ativa??o muscular dos membros inferiores e pelve de volunt?rios h?gidos durante a tarefa de descida degrau. O estudo foi dividido em tr?s cap?tulos: 1) revis?o de literatura; 2) artigo cient?fico; 3) considera??es finais. A revis?o de literatura aborda inicialmente a anatomia de membros inferiores e pelve, seguida das fases e subfase da tarefa de decida de degrau. Em seguida foram abordados a cinem?tica, cin?tica e ativa??o muscular de membros inferiores e pelve durante a tarefa de decida de degrau e uma discuss?o sobre o uso de palmilhas com arco longitudinal medial e sua resposta de forma ascendente aos membros inferiores. O artigo cient?fico avaliou a influ?ncia e os benef?cios das ?rteses plantares quanto a cinem?tica, cin?tica e ativa??o muscular na tarefa de decida de degrau. Como considera??o final apontou que as ?rteses plantares podem alterar a mec?nica articular do p? e dos membros inferiores, fornecendo benef?cios funcionais durante a tarefa de descida de degrau. / Disserta??o (Mestrado) ? Programa de P?s-Gradua??o em Reabilita??o e Desempenho Funcional, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 2018. / Daily, the human locomotor system is challenged to cross different levels of terrain. Going up and down stairs is a common activity of daily living and can be an obstacle when motor function is compromised. Patients with patellofemoral pain complain of retropatellar pain aggravated by activities such as ascent and descent of stairs, with pain being greater during the descent of stairs. The need for control during the step descent task is achieved through eccentric muscle contraction. In the descent of the step, the individuals must actively transport the center of gravity forward and resist gravity during the phase of controlled descent. Studies have been investigating responses of changes in physiological patterns of movement in the feet, believing that these changes can lead to compensations to the lower limbs. Excessive pronation has been linked to numerous functional changes in the lower limbs, indicating excessive use injuries affecting the hip, knee, ankle and foot. Clinicians generally agree that some forms of specialized orthopedic orthoses or footwear can control excessive pronation. Therefore, the present study aims to evaluate the effect of a limb wedge with the kinematics, kinetics and muscular activation of the lower limbs and pelvis of healthy volunteers during the task of descending step. The study was divided into three chapters: 1) literature review; 2) scientific article; 3) final considerations. The literature review initially addresses the anatomy of the lower limbs and pelvis, followed by the phases and sub-phase of the step deciding task. Kinematics, kinetics and muscular activation of the lower limbs and pelvis were discussed during the decision-making task and a discussion about the use of insoles with a medial longitudinal arch and its response ascending to the lower limbs. The scientific article evaluated the influence and benefits of plantar orthoses regarding kinematics, kinetics and muscular activation in the task of deciding step. As a final consideration it was pointed out that the plantar orthoses can alter the joint mechanics of the foot and lower limbs, providing functional benefits during the step descent task.

Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Mecânica, Florianópolis, 2015. / Made available in DSpace on 2016-05-24T17:21:36Z (GMT). No. of bitstreams: 1 338913.pdf: 15783641 bytes, checksum: e4e5e30a9fc572b02430ff4164172aea (MD5) Previous issue date: 2015 / Este trabalho tem como foco o problema de otimização topológica para minimização de massa com restrições locais sobre o campo de tensões de von Mises. Usando conceitos de curvas de nível (ou level sets) para o controle do domínio, desenvolve-se um procedimento de restrição responsável por uma contínua ativação/desativação de um número finito de restrições de tensão local durante a sequência de otimização. As restrições são convenientemente distribuídas sobre o domínio e impostas ao problema através de uma abordagem Lagrangiano aumentado. O principal objetivo da presente tese é criar um algoritmo capaz de identificar as regiões com concentração de tensões e conduzir a topologia para um mínimo local viável. A evolução das curvas de nível utiliza informações da análise de sensibilidade para atualizar a topologia da estrutura. Em um primeiro momento, tendo como finalidade testar a restrição de tensão proposta, emprega-se a clássica equação de Hamilton-Jacobi para a atualização das curvas de nível, uma técnica bastante usada na literatura. Em seguida, uma equação de reação-difusão é usada para orientar, também via evolução das curvas de nível, a sequência de otimização do projeto. Esta última equação de evolução possui duas vantagens. A primeira é a possibilidade de nuclear furos durante o processo de otimização, uma importante característica para um verdadeiro método de otimização topológica. A outra vantagem consiste na eliminação da etapa de reinicialização da função, necessária em evoluções de Hamilton-Jacobi, obtendo melhorias significantes em termos de convergência. Para a solução numérica da equação de reação-difusão, utilizam-se malhas regulares com os tradicionais elementos finitos quadrilaterais e malhas poligonais não-estruturadas, obtidas a partir de tesselações de Voronoi. Vários exemplos em duas dimensões com resultados numéricos bem sucedidos comprovam o bom comportamento da metodologia proposta para detectar concentrações de tensões e propor um projeto viável.<br> / Abstract : This work focuses on topology optimization for mass minimization with local constraints on the von Mises stress field. Within a level-set context to control the domain, it is developed a constraint procedure that accounts for a continuous activation/deactivation of a finite number of local stress constraints during the optimization sequence. Such constraints are conveniently distributed over the domain and imposed to the problem through an augmented Lagrangian approach. The main objective is to create an efficient algorithm capable of identifying stress concentration regions and drive the topology to a feasible local minimum. The level set evolution makes use of information of the sensitivity analysis to update the structural topology. Initially, being the main goal testing the proposed stress constraint, the level set updating is accomplished by the classical Hamilton-Jacobi equation, widely employed in the literature. Next, a reaction-diffusion equation is used to guide, also via evolution of a level set, the design optimization sequence. The advantages of the latter evolution equation are twofold. Firstly, it allows the creation of new holes during the optimization process, a significant feature for a true topological optimization method. Secondly, reinitialization steps usually found in Hamilton-Jacobi based evolution are eliminated with a significant improvement in convergence. The numerical solution of the reaction-diffusion equation is performed by using regular meshes with standard quads and unstructured polygonal meshes obtained from Voronoi tessellations. A set of benchmark examples in two dimensions achieving successful numerical results assesses the good behavior of the proposed methodology to detect stress concentrations and propose a feasible design.