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The Effects of Adolescent Nicotine Exposure on Adult Rat Serial Pattern LearningPickens, Laura Renee Glass 09 July 2009 (has links)
No description available.
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Evaluation of the Brainstem Spinal Cord Preparation in the Neonatal Rat as a Model for Prenatal Nicotine ExposureLevine, Richard January 2012 (has links)
Class of 2012 Abstract / Specific Aims: The goal of this project was to evaluate the use of a preparation of the brainstem and spinal cord of neonatal rats that has been widely used for observing and quantifying central nervous activity, as well as the response to pharmacological manipulation. To achieve this, we specifically aimed to remove the intact brainstem and spinal cord of newborn rats, and develop a preparation that would maintain physiological function and allow for recording of electrical activity.
Methods: Multiple dissections were performed on neonatal rats. Conditions during the dissections were controlled to maintain physiological function. Once removed, the intact brainstem and spinal cord was placed in a preparation that allowed for manipulation and access to nerve rootlets. Finally, glass suction electrodes were used to record electrical activity directly from the nerve rootlets. Once recorded, the data were stored on a hard drive for further analysis.
Main Results: We were successful in isolating the intact brainstem and spinal cord in neonatal rats while maintaining physiological conditions and nervous activity. The preparation allowed for easy access to nerve roots as well as customization for different experiments. We were also successful in recording nerve activity in the preparation and collection of data for use in future experiments
Conclusions: We conclude that the brainstem spinal cord preparation described in this study is a valuable tool that allows for recording and analysis of nerve activity, and specifically for measurement of respiratory motor output. This is a preparation that can be used in a variety of experiments that attempt to observe or quantify the activity of central nerve cells and allows for pharmacological interventions that could be applied in various experiments.
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The Effects of Adolescent Nicotine Exposure on Adult Memory for Stimulus Attributes and Extinction LearningCullen, Patrick Kennedy 24 June 2011 (has links)
No description available.
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The Effects of Chronic Adolescent Nicotine Exposure on Adult Cognition in the Male and Female RatPickens, Laura R. G. 28 November 2012 (has links)
No description available.
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Epigenetic effects of adolescent nicotine exposure on rat serial pattern learningRenaud, Samantha Marie 18 July 2013 (has links)
No description available.
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