Despite mounting evidence, a question still exists as to the true clinical relevance of varying degrees of malnutrition, the role of currently measured nutritional parameters in identifying malnutrition and predicting clinical risk in individual patients, and the efficacy of nutritional therapy. This study was designed to document the usefulness of the Prognostic Nutritional Index (PNI) as a predictor of clinical course. The nutritional assessments and clinical records of 328 subjects in a Veterans Administration Hospital were reviewed, PNI and complication rates were determined for each of the subjects, and the data statistically analyzed. The PNI was found to be a useful indicator of malnutrition and predictor of clinical course. The PNI appeared to be a more sensitive index of clinical outcome than did comparison of individual nutritional parameters to accepted norms, although it accounted for only 17% of the information needed to predict clinical course perfectly.

Made available in DSpace on 2015-03-26T13:55:31Z (GMT). No. of bitstreams: 1 texto completo.pdf: 162034 bytes, checksum: eb0e927258e22712193fc49665f832bc (MD5) Previous issue date: 2007-08-09 / A study was accomplished with the objective of determining the level of Spray Dried plasma (SDP) to be used in substitution to the powdered skimmed milk in diets without antibiotics for pigs weaned to the 21 days of age. 108 barrous and female pigs were used, with initial weight of 6,05± 0,35 Kg, distributed in experimental blocks randomized, with four treatments, nine blocks and three animals for experimental unit. The treatments consisted of levels of inclusion of 0,0; 2,5; 5,0 and 7,5% of SDP in the Period I (of the 22 to the 28 days of age); 0,0; 1,25; 2,50; 3,25 of SDP in the Period II (of the 29 to the 35 days of age). Blocks was constituted in function of the initial weight of the animals, the animals were maintained in the experiment up to 49 days of age. The relationship aminoacid was maintained between the lisina and the other essential amino acids, with base in the concept of ideal protein for piglets in the phase pré-initial. The ration consumption and the weight gain of the animals were influenced by the levels of inclusion of SDP in the period I (P <0,10), the bio- nutritional index indicated an improvement in the feed conversion (P <0,05) without difference of the diarrhea occurrence (P>0,05). There was no effect (P>0,10) of the treatments on the consumption of ration of the pigs in the period I+II. However, the increment of the levels of SDP provided increase in the weight gain (P<0,10) and the bio-nutritional index indicated an improvement in the feed conversion (P<0,05), doesn't tend significant difference in the diarrhea occurrence (P>0,05). In the period I+II+III the treatment four that understood the animals that consumed 7,5% of SDP the first week and 3,75% in the second week pós-weaning it differed of the other treatments on the consumption of ration of the pigs, on the medium daily gain (P <0,10) and on the bio-nutritional index (P <0,05), in the case of the diarrhea occurrence it was smaller in the treatments that had plasma. The levels of inclusion of spray dried plasma in diets without antibiotics for pigs of 5,0% in the period I, 2,5% in the period II. / Foi realizado um estudo com o objetivo de se determinar o nível de plasma sanguíneo em pó (PSP) a ser usado em substituição ao leite desnatado em pó em dietas sem antibióticos para leitões desmamados aos 21 dias de idade. Foram utilizados 108 leitõesmachos e fêmeas, com peso inicial de 6,05± 0,35 Kg, distribuídos em delineamento em blocos ao acaso, com quatro tratamentos, nove blocos e três animais por unidade experimental. Os tratamentos consistiram de níveis de inclusão de 0,0; 2,5; 5,0 e 7,5% de PSP no Período I (dos 22 aos 28 dias de idade); 0,0; 1,25; 2,50; 3,25 de PSP no Período II (dos 29 aos 35 dias de idade). O bloco foi constituído em função do peso inicial dos animais, os animais foram mantidos no experimento até 49 dias de idade. Foi mantida a relação aminoacídica entre a lisina e os demais aminoácidos essenciais, com base no conceito de proteína ideal para suínos na fase pré- inicial. O consumo de ração e o ganho de peso dos animais foram influenciados pelos níveis de inclusão do PSP no período I (P<0,10), o Índice bionutricional indicou uma melhoria na conversão alimentar (P<0,05) sem diferença da ocorrência de diarréia (P>0,05). Não houve efeito (P>0,10) dos tratamentos sobre o consumo de ração dos leitões no período I+II. Entretanto, o incremento dos níveis de PSP proporcionou aumento no ganho de peso (P<0,10) e o Índice bionutricional indicou uma melhora na conversão alimentar (P<0,05), não tendo diferença significativa na ocorrência de diarréia (P>0,05). No período I+II+III que foi dos 22 aos 49 dias o tratamento 4 que compreendeu os animais que consumiram 7,5% de PSP na primeira semana e 3,75% na segunda semana pós-desmame diferiu dos outros tratamentos sobre o consumo de ração dos leitões, sobre o ganho diário médio (P<0,10) e sobre o índice bionutricional (P<0,05), no caso da ocorrência de diarréia foi menor nos tratamentosque tiveram plasma. Os níveis de inclusão de plasma sanguíneo em pó em dietas sem antibióticos para leitões de 5,0% no período I, 2,5% no período II.