Thesis (Ph.D.)--Duquesne University, 2008. / Title from document title page. Abstract included in electronic submission form. Includes bibliographical references (p. 67-72) and index.

Thesis (Ph.D.)--University of Delaware, 2007. / Principal faculty advisor: Ronet Bachman, Dept. of Sociology & Criminal Justice. Includes bibliographical references.

No description available.

The basis for sex differences in cognitive ability remains poorly defined and controversial both scientifically and politically. One of the biological hypotheses on sex differences, of particular relevance to this thesis, concerns the role of gonadal steroids, specifically testosterone (T) and oestrogen, and their relationship to individual differences in the performance of specific cognitive tasks. In addition, the role that age-related changes in these hormones play in relation to generalised and pathological cognitive ageing in males is studied. It is important to determine whether decreases in T levels that occur with ageing in males are associated with age-related decreases in cognitive performance because T levels can potentially be modified. Males have consistently been found to outperform females on measures of visuo-spatial function; performance on the Vandenberg and Kuse Mental Rotation Test (MRT) shows the largest and most robust of sex differences. Gonadal steroids have both organisational and activational effects which contribute to both withinsex variability and between-sex differences in visuo-spatial cognition. As males age, endogenous plasma T levels decline gradually yet variably between individuals. Studies in older males show improvement in visuo-spatial cognition following T supplementation; however, it remains to be resolved whether decreases in endogenous T levels with ageing are associated with poorer MRT performance. Some recent studies in older males have reported positive correlations between measures of plasma T levels and cognitive functioning, including processing speed and executive function measures. These data are inconsistent, however, and important questions remain concerning, for example: the age at which the effect is strongest; whether there are different effects at different ages; whether there is an optimal level at which T levels affect particular abilities; and which abilities show the strongest association with endogenous plasma T levels. Increased intra-individual variability in performance on Choice Reaction Time (RT) tasks has recently been shown to be a strong predictor of cognitive functioning in university students. Methodological advances in the analyses of RT distributions has allowed for the calculation of robust estimates of intra-individual RT variability. The association between these estimates and cognitive performance in middle and older aged males, however, remains to be determined. Further, the association between endogenous plasma T levels and intra-individual RT variability in aged males is unknown. The thesis addresses these issues; firstly, through cross-sectional analyses of the associations between different measures of plasma T levels, learning and memory, processing speed, and executive function performance in a large population based sample of 1046 men aged between 35 and 81 years. Secondly, further cross-sectional analyses are reported from a subsequent study in a healthy sub-sample of 96 of these men on the associations between endogenous plasma T levels, MRT performance, constituent abilities related to MRT performance, and performance on composite measures of both processing speed and executive function. In a third study, these data are re-analysed in relation to intra-individual variability in RT performance. In light of the results of these studies, the role that age-related declines in plasma T levels play in relation to generalised age-related cognitive decline in males is discussed. / http://proxy.library.adelaide.edu.au/login?url= http://library.adelaide.edu.au/cgi-bin/Pwebrecon.cgi?BBID=1330807 / Thesis (Ph.D.) -- University of Adelaide, School of Psychology and School of Medicine, 2008

This hermeneutical study interprets and describes the phenomena of ageing and living with disability. The lived experiences of 14 older men and the horizon of this researcher developed an understanding of what it is like for men to grow old and, for some, to live with the effects of a major disability. The study is grounded in the philosophical hermeneutics of Gadamer and framed in the context of embodiment, masculinity, and narrative. I conducted multiple in-depth interviews with older men aged from 67 to 83 years of age. Seven of the participants had experienced a stroke and I was able to explore the phenomenon of disability with them. Through thematic and narrative analyses of the textual data interpretations were developed that identified common meanings and understandings of the phenomena of ageing and disability. These themes and narratives reveal that the men�s understandings are at odds with conventional negative views of ageing and disability. These older men are �alive and kicking�, they voice counternarratives to the dominant construction of ageing as decline and weakness, and have succeeded in remaking the lifeworld after stroke. Overall I have come to understand an overarching meaning of older men �working it out� as illustrative of a strong face of ageing and disability. Older men seek out opportunities to participate actively in community life and, despite the challenges of ageing and disability, lead significant and meaningful lives. These findings challenge and extend our limited understandings of men�s experiences of ageing and living with disability. This interpretation offers gendered directions for policy development, clinical practice, and future research.

This hermeneutical study interprets and describes the phenomena of ageing and living with disability. The lived experiences of 14 older men and the horizon of this researcher developed an understanding of what it is like for men to grow old and, for some, to live with the effects of a major disability. The study is grounded in the philosophical hermeneutics of Gadamer and framed in the context of embodiment, masculinity, and narrative. I conducted multiple in-depth interviews with older men aged from 67 to 83 years of age. Seven of the participants had experienced a stroke and I was able to explore the phenomenon of disability with them. Through thematic and narrative analyses of the textual data interpretations were developed that identified common meanings and understandings of the phenomena of ageing and disability. These themes and narratives reveal that the men�s understandings are at odds with conventional negative views of ageing and disability. These older men are �alive and kicking�, they voice counternarratives to the dominant construction of ageing as decline and weakness, and have succeeded in remaking the lifeworld after stroke. Overall I have come to understand an overarching meaning of older men �working it out� as illustrative of a strong face of ageing and disability. Older men seek out opportunities to participate actively in community life and, despite the challenges of ageing and disability, lead significant and meaningful lives. These findings challenge and extend our limited understandings of men�s experiences of ageing and living with disability. This interpretation offers gendered directions for policy development, clinical practice, and future research.

Thesis (M.F.A.)--George Mason University, 2007. / Title from PDF t.p. (viewed Jan. 21, 2008). Thesis director: Peggy Feerick. Submitted in partial fulfillment of the requirements for the degree of Master of Fine Art in Art and Visual Technology. Vita: p. 58. Includes bibliographical references (p. 55-56). Also available in print.

Thesis (Ph.D.) -- University of Adelaide, School of Psychology and School of Medicine, Discipline of Medicine, 2008. / "Thesis submitted in fulfilment of the Degree of Doctor of Philosophy, January 2008" Includes author's previously published papers. Bibliography: leaves 123-157. Also available in print form.

Progressive resistance training (PRT) in the elderly has commonly used ATPase histochemistry to evaluate fiber type changes, but evidence shows there are myosin heavy chain (MHC) hybrids in aging muscle that cannot be classified by histochemistry. The purpose of this study was to assess the MHC and whole muscle alterations following a 12-week PRT protocol. Seven healthy men (age=74.0±4.7, weight=74.6±13.5kg) underwent testing for 1-repetition maximum (1-RM), whole muscle (thigh) crosssectional area (CSA) by computed tomography, and a needle muscle biopsy from the vastus lateralis for analysis of MHC, pre- and post-training. The PRT consisted of 2 sets of 10 repetitions, and a third set to volitional exhaustion at 80% 1-RM, 3 days per week for 12 weeks. Muscle ATPase histochemistry analysis for distribution did not significantly differ following training. Muscle samples were freeze dried and dissected for MHC analysis (sodium dodecyl sulfate-polyacrylamide gel electrophoresis (5% gel) and silver stained; 224.0±11.2 and 213.0±8.1 fibers/subject pre-/post-training; total fibers analyzed=3059). MHC analysis demonstrated significant increases in MHC I proportion (10.4%; P<0.05), and significant decreases in MHC UIIa (9.0%; P<0.05), UIIa/x (0.9%; P<0.05), and IIa/x (8.9%; P<0.05) isofroms, along with no change in the MHC Ila and IIx isoforms, pre- versus post-training. In addition, 1-RM (51.9%; P<0.05) and CSA (5.9%; P<0.05) increased from pre- to post-testing. This data supports previous whole muscle changes, more important, is the increase in MHC I and decrease in MHC I/IIa, I/IIa/IIx, and IIa/x hybrids. The myosin light chain 3f (MLC3f) to MLC 2 ratio did not change with the PRT in either the MHC I or MHC IIa isoforms, although there was a significantly greater amount of MLC 3f in the MHC Ila versus the MHC I fibers (p<0.05), pre- and post-training. The myosin isofrom data provides support that aging muscle has the plasticity to adapt in a manner unlike that of young muscle. / School of Physical Education

Thesis (Ph. D.)--University of Sydney, 2002. / Title from title screen (viewed Apr. 23, 2008). Submitted in fulfilment of the requirements for the degree of Doctor of Philosophy to the School of Behavioural and Community Health Sciences, Faculty of Health Sciences. Degree awarded 2002; thesis submitted 2001. Includes bibliography. Also available in print form.