Bluetooth Piconet has become an important area of research and development in the short-range wireless network system. It is well known that bluetooth causes disturbing interference since sharing frequency band is used in communication channels. This thesis proposes a new and efficient method to solve the retransmission problem that occurs in wireless interference. The proposed method is developed based on average transmit times and margin of grouping to find out the grouping rule of the Bluetooth Piconet. A computer simulation shows in this thesis that the performance of the proposed group assignment approach is much bettter than can be obtained by other conventional means. Furthermore, in order to reduce retransmit time and save time-slot, a new packet combine retransmit method is developed based on different reliability of packet's transmit conditions in this thesis. As a consequence, for total duty cycle and time slots, the proposed packet combine retransmit method obtains a better performance than the conventional retransmit method.