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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Bidens sulphurea (Sch. Bip.): efeitos fotodinâmico e antibiótico dos extratos etanólicos de suas flores

Araújo Neto, Alexandre Dias de 31 August 2011 (has links)
This work had the aim to assess some biological eects of the Bidens sulphurea (Asterace ) (also know as Cosmos sulphureus), assessed eects were: cytotoxicity, antibiotic and phototoxicity. The phototoxicity was ephasized, since the primary aim of this work was to evaluate if this plant\'s pigments could be used as photosensitizers in the photodynamic therapy, in a non invasive way, using light emitted by LED, for treatment of dermatosis, particularly, onicomicosis. The conclusion of this work is that, of the two Bidens sulphurea varieties studied, the one that bear the greater photodynamic activity, when irradiated with white light, or red light ( 600 nm) and did showed greater antibiotic eect (in the dark) was the orange variety. The orange variety did showed an increase in the toxicidy to the Artemia salina nauplii, when irradiated with red light. / Este trabalho teve por objetivo, avaliar alguns efeitos biologicos do extratos bruto (etanolico) das ores de Bidens sulphurea (Asterace), os efeitos avaliados foram: citotoxicidade, efeito antibiotico e fototoxico. Deu-se ênfase aos efeitos fototoxicos, pois o objetivo primario era avaliar se os pigmentos desta planta poderiam ser utilizados como fotosensitizadores para a terapia fotodinâmica, empregando-se luz emitida por LED, para o tratamento de um modo não invasivo de dermatoses, tais como a onicomicose. Concluiuse que, das duas variedades da planta estudada (variedades laranja e amarela), a que apresenta maior fototoxicidade tanto quando irradiado por luz branca, e vermelha ( 600 nm), quanto efeito antibiotico (no escuro) foi a variedade laranja, a qual tambem mostrou uma grande toxicidade frente aos nauplios de Artemia salina quando irradiada com luz vermelha. / Mestre em Química

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