M.Cur. (Obstetrics and Neonatal Nursing) / A premature baby is physiologically and neurologically immature and does not always react as desired to the extra-uterine environment. A possible way to stimulate babies is by playing slow baroque music to them. The purpose of the study was to determine what effect slow baroque.music has on the heart rate, respiratory rate, saturation, blood pressure and motor movements of premature babies. The effect of slow baroque music on premature babies was investigated by means of an extensive literature study, but only limited research on premature babies was found. A preparatory study was used to determine whether slow baroque music has a positive effect on the behaviour of premature babies. Ten premature babies were then used as case studies to determine the effect of slow baroque music on their heart and respiratory rates, saturation, blood pressure and motor movements. The following conclusions were reached by statistically processing the results: • Slow baroque music had a positive and significant effect on the babies' respiratory rate and motor movements. • The heart rate, saturation and blood pressure of the babies showed a slight positive effect only. Nursing guidelines were established for playing baroque music to premature babies and recommendations were made for further research.