Thesis (M.A. (Heritage and Museum studies))--University of Pretoria, 2002. / Summary in English. Includes bibliographical references.

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Orientador: Anaglória Pontes / Resumo: O câncer de mama é uma doença maligna relativamente comum em mulheres adultas jovens, justificando a preocupação com a potencial toxicidade gonadal relacionada à quimioterapia. É importante considerar o encaminhamento precoce de pacientes jovens com câncer de mama que tenham desejos reprodutivos para especialistas, a fim de discutir sobre a preservação da fertilidade. A criopreservação de embriões ou de oócitos estão entre os principais métodos à disposição, e para conseguir isso, estimulação ovariana controlada (EOC) é o primeiro passo a ser considerado. O presente estudo tem como objetivo apresentar protocolo de estimulação ovariana em para preservação da fertilidade em pacientes com câncer de mama. De novembro de 2014 a dezembro de 2016, 109 pacientes com câncer de mama com menos de 40 anos de idade foram selecionadas para preservar seu potencial reprodutivo. Elas foram divididas de acordo com a fase do ciclo menstrual em que o estímulo ovariano foi iniciado: fase folicular inicial, fase folicular tardia e fase lútea. Para reduzir o tempo necessário da obtenção dos oócitos, este estudo utilizou o princípio do início aleatório, no qual a EOC pode ser iniciada durante qualquer período do ciclo menstrual sem consequências negativas. O letrozol foi utilizado durante toda a estimulação para diminuir as concentrações de estradiol, independentemente da imunohistoquímica tumoral. Na presença de tumores positivos ao estradiol, e indicação de quimioterapia neoadjuvante, o tamoxi... (Resumo completo, clicar acesso eletrônico abaixo) / Abstract: Breast cancer is a relatively common malignancy in young adult women, justifying the concern about the potential gonadal toxicity related to chemotherapy. It is important to consider early referral of young breast cancer patients with reproductive desires to fertility specialists, in order to discuss the fertility preservation. Embryos or oocytes cryopreservation are among the main methods available, and to achieve that, controlled ovarian stimulation (COS) is the first step to be considered. From November 2014 to December 2016, 109 breast cancers patients under 40 years were enrolled to preserve their reproductive potential. They were divided according to the menstrual cycle status in: initial follicular phase, late follicular phase and luteal phase. In order to reduce the time necessary to obtain the oocytes, this study used the principle of random start, in which the COS can be initiated during any period of the menstrual cycle without negative consequences. Letrozole was used during all stimulation to reduce estradiol concentrations, regardless of tumor immunohistochemistry. In the presence of estradiol positive tumors, and indication of neoadjuvant chemotherapy, tamoxifen was administerd as an additional protective measure. A GnRH agonist was used to trigger ovulation, in order to mitigate the risk of ovarian hyperstimulation syndrome. The following parameters were analyzed: age, day of COS start, number of days required to COS, total FSH dosage, estradiol levels at fi... (Complete abstract click electronic access below) / Mestre

abstract: Civic identity in San Diego emerged first from a complex set of Native, Spanish and Mexican traditions. However, after 1850 Americans from the East coast and Midwest arrived and brought with them to San Diego a strong sense of how to both build and manage towns. These regional influences from other parts of the country carried over into the early twentieth century, and began to reshape civic identity and the first historic preservation movements in San Diego. This dissertation establishes San Diego's place in the scholarly literature of the urban West and historic preservation. After a brief background of San Diego history, this study begins with an explanation of the dual efforts at work in San Diego after 1945 to build for the future while preserving the past. Next, this study examines the partnerships formed and conflicts between promoters for development and advocates of preservation. The progression of historic preservation efforts in San Diego since WWII includes missed opportunities, lapses in historic authenticity, and divisions about what buildings or stories to preserve. This study describes how conflicts were resolved and explains the impact of those outcomes on historic preservation and authenticity. San Diego's history has much in common with many cities in the American West, but the historic narrative of San Diego also differs from other Western cities in several compelling ways. First, San Diego bears distinction as the oldest city in California and one of the oldest cities in the West. Second, historic preservation in San Diego has yet to be fully explored by scholars. Third, some of preservation conflicts explored in this study reveal distinct differences from preservation debates in other urban areas. Using government, organizational, and archival records, secondary sources, interviews, and personal observation, this dissertation explains how historic preservation in San Diego became an integral part of city planning, an expectation of residents and visitors, and a key feature of the city`s civic identity. This study contributes to Western scholarship by bringing San Diego into the literature of historic preservation and the urban West. / Dissertation/Thesis / Ph.D. History 2011

abstract: Pavement preservation is the practice of selecting and applying maintenance activities in order to extend pavement life, enhance performance, and ensure cost effectiveness. Pavement preservation methods should be applied before pavements display significant amounts of environmental distress. The long-term effectiveness of different pavement preservation techniques can be measured in terms of life extension, relative benefit, and benefit-cost ratio. Optimal timing of pavement preservation means that the given maintenance treatment is applied so that it will extend the life of the roadway for the longest possible period with the minimum cost. This document examines the effectiveness of chip seal treatment in four climatic zones in the United States. The Long-Term Pavement Performance database was used to extract roughness and traffic data, as well as the maintenance and rehabilitation histories of treated and untreated sections. The sections were categorized into smooth, medium, and rough pavements, based upon initial condition as indicated by the International Roughness Index. Pavement performance of treated and untreated sections was collectively modeled using exponential regression analysis. Effectiveness was evaluated in terms of life extension, relative benefit, and benefit-cost ratio. The results of the study verified the assumption that treated sections performed better than untreated sections. The results also showed that the life extension, relative benefit, and benefit cost ratio are highest for sections whose initial condition is smooth at the time of chip seal treatment. These same measures of effectiveness are lowest for pavements whose condition is rough at the time of treatment. Chip seal treatment effectiveness showed no correlation to climatic conditions or to traffic levels. / Dissertation/Thesis / M.S. Civil Engineering 2012

Orientador: Lindsay Unno Gimenes / Coorientador: Fabio Morato Monteiro / Coorientador: Moyses dos Santos Miranda / Coorientador: Rinaldo Batista Viana / Banca: Marcílio Nichi / Banca: Rubens Paes de Arruda / Resumo: A criopreservação provoca injúrias aos espermatozoides e necessita de métodos que minimizem esses danos. Embora seja bastante discutida, a remoção do plasma seminal tornou-se uma alternativa para melhorar a qualidade e viabilidade espermática após a congelação e vem sendo utilizada em outras espécies na tentativa de obter bons resultados. O objetivo deste estudo foi comparar a remoção do plasma seminal de bubalinos tanto por filtragem (SpermFilter®) quanto por centrifugação sobre a qualidade do sêmen descongelado de búfalos. Foram utilizados sete touros da raça Murrah, os quais foram submetidos à colheita de sêmen por vagina artificial uma vez por semana. Os ejaculados foram diluídos com Botu-Bov® e fracionados em alíquotas para confrontar três técnicas antes da congelação: grupo C (Criopreservação convencional com plasma seminal), grupo CE (Criopreservação removendo o plasma seminal por centrifugação) e grupo F (Criopreservação removendo o plasma seminal por filtragem). O sêmen fresco foi analisado quanto ao volume, aspecto, cor, concentração (câmara de Neubauer), turbilhonamento, motilidade progressiva, vigor e morfologia espermática. No sêmen descongelado, foram avaliados a cinética espermática pelo CASA, a integridade de membrana plasmática, acrossoma, potencial de membrana mitocondrial e quantificação de EROs por citometria de fluxo e, adicionalmente, foi estimado o grau de peroxidação lipídica pela técnica de TBARS. Os resultados revelam que a remoção de plasma seminal ... (Resumo completo, clicar acesso eletrônico abaixo) / Abstract: Cryopreservation promotes injury to sperm and methods to minimize such damage are necessary. Although much discussed, removal of seminal plasma that has been successfully used in other species has become an alternative for improving sperm quality and viability after freezing. The aim of the present study was compare to removal seminal plasma in buffalo both by filtering (SpermFilter®) and by centrifugation on the quality frozen thawed buffalo semen. For this purpose, semen of seven Murrah buffalo-bulls, which were submitted to semen collection by artificial vagina once a week. The samples were diluted with Botu-Bov® and were fractionated in aliquots to confront three techniques before freezing: C group (conventional cryopreservation with seminal plasma), CE group (cryopreservation removing the seminal plasma centrifuge) F group (Cryopreservation removing the seminal plasma with Sperm Filter®). Fresh semen was analyzed for volume, appearance, color, concentration (Neubauer chamber), gross motility, progressive motility, vigor and sperm morphology. In the thawed sperm, sperm kinetics was evaluated by CASA, plasma membrane and acrosomal integrity, mitochondrial membrane potential and estimation of the levels of reactive oxygen species were assigned by flow cytometry and was estimated degree of lipid peroxidation by TBARS technique. The results show that the removal seminal plasma did not improve sperm kinetics, mitochondrial membrane potential and does not modify the degree of l... (Complete abstract click electronic access below) / Mestre

This thesis analyzes the English National Trust’s interpretation of the making and reception of Stowe Landscape Garden. Specifically, this is a critique of the Trust’s narrative of nationalism, which is overlaid by the use of romantic interpretive themes. Arguably, Stowe’s first contribution was the combination of expressions of nature through landscape with architectural and sculptural monuments of Englishness. The National Trust, however, has combined interpretations of multiple landscape gardens across a century, thus blurring its actual significance. Stowe has been lumped into a jumbled framework of anachronistic landscape commentary much based in the literature of reception. The use of receptive history as fact to define concepts like ‘Englishness’, ‘Landscape Garden’, and the ‘Picturesque’ only further aid the unsustainable development of the historical landscape. Stowe is recognized as the most extensive extant landscape garden to exemplify contributions by the first four designers in the medium: Vanbrugh, Bridgeman, Kent, and Brown. Lancelot ‘Capability’ Brown’s place-making role in the history of English landscape, much derided by the proponents of the Picturesque, found its first expression at Stowe from 1740 to 1751. Thus, Stowe’s Brownian dominant landscape, of which the bones are still largely intact, should be used as the designated period of interpretation. In this way, the National Trust could fulfill a modern desire for connection to nature, and with greater specificity, diversity and transparency in historical accounts, expand the accessibility of ‘Englishness’ in the form the consummate national landscape garden.

Submitted by Sérgio Ricardo Losnak (sergiolosnak@gmail.com) on 2018-07-02T19:30:14Z No. of bitstreams: 1 Sergio Losnak - Dissertação Final.pdf: 4316643 bytes, checksum: dd25415cac52b23e14a916d78c72a644 (MD5) / Approved for entry into archive by Lucilene Cordeiro da Silva Messias null (lubiblio@bauru.unesp.br) on 2018-07-02T20:19:01Z (GMT) No. of bitstreams: 1 losnak_sr_me_bauru.pdf: 4296854 bytes, checksum: 02a8c9d777e2b59ab9fb183eafe1d080 (MD5) / Made available in DSpace on 2018-07-02T20:19:01Z (GMT). No. of bitstreams: 1 losnak_sr_me_bauru.pdf: 4296854 bytes, checksum: 02a8c9d777e2b59ab9fb183eafe1d080 (MD5) Previous issue date: 2018-06-15 / As questões relacionadas à preservação do patrimônio ferroviário no Brasil têm ganhado maior dimensão nas últimas décadas, não só diante da obsolescência tecnológica, mas principalmente devido ao processo de privatização de empresas estatais do setor. As particularidades desta tipologia de patrimônio vêm permitindo múltiplas possibilidades da sua transformação em equipamentos culturais, como museus, centros de documentação e espaços de cultura e de turismo que são viabilizados ou incentivados por meio das políticas públicas de preservação implementadas pela União, estados e municípios. No campo acadêmico verifica-se um reduzido número de trabalhos que investigam as particularidades, práticas, métodos e até mesmo resultados relacionados às políticas públicas que atuam na preservação ferroviária. É diante desse contexto que este trabalho busca caracterizar as práticas das políticas públicas no estado de São Paulo, mais especificamente da cidade de Bauru, tendo como objetos o Conselho de Defesa do Patrimônio Cultural e o Museu Ferroviário Regional. Esses mecanismos de proteção estão presentes em muitos municípios e se tornaram a principal ferramenta de preservação de bens ferroviários. Em termos metodológicos, o trabalho contará com pesquisa bibliográfica exploratória sobre o tema, análise documental e entrevistas com agentes envolvidos no processo. Como resultado, pretende-se chegar à compreensão das diretrizes, conceitos, valores e agentes que atuam na preservação por meio das políticas públicas, indicando-nos o possível método de musealização como prática principal quando se trata do patrimônio industrial ferroviário, não só na cidade de Bauru como também em outros municípios do estado de São Paulo. / The issues related to the preservation of railway heritage in Brazil is getting more and more importance in last decades, not only due to the technological obsolescence, but mainly due to privatization process of the companies in the sector. The characteristics of that kind of heritage have allowed many possibilities in its transformation in cultural equipment, such as museums, document center and cultural and tourism spaces that are encouraged by the country, states and cities. There are a few works in academic field that investigate the particularities, practices, methods and even results related to the public policies that act in railway preservation. In this context, this work aims to characterize public policies practices in São Paulo state, more specifically at Bauru city, having as the research object the Council of Defense of Cultural Heritage and the Regional Railway Museum. These protection mechanisms are presents in many municipalities and they became the main tool for the preservation of railway goods. In methodological terms, the research will have exploratory bibliographic research, documentary analysis and interviews with agents related in the process. As a result, we intend to comprehend the guidelines, concepts, values and agents that act in the preservation through public policies, indicating us the possible method of musealization as main practice for the industrial railway heritage, not only in Bauru city, but also in other municipalities in São Paulo State

The growth of data/information on social media and in large organizations is huge in terms of velocity, volume and variety which is also something being tackled by the large IT companies providing Big Data solutions. The other challenges which are linked to managing the huge pile of data are about ensuring preservation and access of crucial data which has implications in every sector ranging from pharmaceuticals to aerospace and cultural institutions (museums, archives and governmental records). The challenges for data management are further complicated by the changing infrastructure landscape and the new business models to host data in virtualized cloud-based storage termed as Cloud solutions (PaaS, SaaS, and IaaS). Several large companies and public institutions are migrating their data/applications to cloud due to the apparent benefits of scalability, reliability, cost, easy of operability and security. The digitization and maintenance of e-records / digital archives in Cloud provides many potential benefits but it is also prone to several risks to ensure long-term retention of data as well as to ensure integrity, authenticity and accessibility of data. For several organizations such as memory institutions, heavy industries (Aerospace & Defence), banks and pharmaceutical companies, it is business critical to securely store data for long-term with integrity, authenticity and accessibility ensured. Hence, along with preservation of data, it is crucial to keep integrity and authenticity of data intact. The digital forensics methods and tools offer several solutions to ensure preservation of data and detect risks at pre-ingest stage of digital archiving to take appropriate measures towards ensuring authenticity, integrity and accessibility. The specific forensics methods and tools also offers possibilities to detect malicious activities or tampering in the digital archives and prepare report for presentation in the court. This thesis work is focussed on the applications of digital forensics towards ensuring the preservation of data in cloud-based storage. It discusses the applications of processes, methods and tools to improve the acquisition, management and accessibility of collections hosted on cloud-based storage (Google Drive, Sky Drive). The pilot platform (i.e. Google Drive) would be tested with forensics methods/tools to draw conclusions for the memory institutions about hosting their data on cloud storage.

Orientador: Eduardo Romero de Oliveira / Banca: Nilson Ghirardello / Banca: Marília Xavier Cury / Resumo: As questões relacionadas à preservação do patrimônio ferroviário no Brasil têm ganhado maior dimensão nas últimas décadas, não só diante da obsolescência tecnológica, mas principalmente devido ao processo de privatização de empresas estatais do setor. As particularidades desta tipologia de patrimônio vêm permitindo múltiplas possibilidades da sua transformação em equipamentos culturais, como museus, centros de documentação e espaços de cultura e de turismo que são viabilizados ou incentivados por meio das políticas públicas de preservação implementadas pela União, estados e municípios. No campo acadêmico verifica-se um reduzido número de trabalhos que investigam as particularidades, práticas, métodos e até mesmo resultados relacionados às políticas públicas que atuam na preservação ferroviária. É diante desse contexto que este trabalho busca caracterizar as práticas das políticas públicas no estado de São Paulo, mais especificamente da cidade de Bauru, tendo como objetos o Conselho de Defesa do Patrimônio Cultural e o Museu Ferroviário Regional. Esses mecanismos de proteção estão presentes em muitos municípios e se tornaram a principal ferramenta de preservação de bens ferroviários. Em termos metodológicos, o trabalho contará com pesquisa bibliográfica exploratória sobre o tema, análise documental e entrevistas com agentes envolvidos no processo. Como resultado, pretende-se chegar à compreensão das diretrizes, conceitos, valores e agentes que atuam na preservação por meio das... (Resumo completo, clicar acesso eletrônico abaixo) / Abstract: The issues related to the preservation of railway heritage in Brazil is getting more and more importance in last decades, not only due to the technological obsolescence, but mainly due to privatization process of the companies in the sector. The characteristics of that kind of heritage have allowed many possibilities in its transformation in cultural equipment, such as museums, document center and cultural and tourism spaces that are encouraged by the country, states and cities. There are a few works in academic field that investigate the particularities, practices, methods and even results related to the public policies that act in railway preservation. In this context, this work aims to characterize public policies practices in São Paulo state, more specifically at Bauru city, having as the research object the Council of Defense of Cultural Heritage and the Regional Railway Museum. These protection mechanisms are presents in many municipalities and they became the main tool for the preservation of railway goods. In methodological terms, the research will have exploratory bibliographic research, documentary analysis and interviews with agents related in the process. As a result, we intend to comprehend the guidelines, concepts, values and agents that act in the preservation through public policies, indicating us the possible method of musealization as main practice for the industrial railway heritage, not only in Bauru city, but also in other municipalities in São Paulo Stat... (Complete abstract click electronic access below) / Mestre