Oregon State University has hosted an International Atomic Energy Agency (IAEA) International Collaborative Standard Problem (ICSP) through testing conducted on the Multi-Application Small Light Water (MASLWR) facility. The MASLWR facility features a full-time natural circulation loop in the primary vessel and a unique pressure suppression device for accident scenarios. Automatic depressurization system (ADS) lines connect the primary vessel to a high pressure containment (HPC) which dissipates steam heat through a heat transfer plate thermally connected to another vessel with a large cool water inventory. This feature drew the interest of the IAEA and an ICSP was developed where a loss of feedwater to the steam generators prompted a depressurization of the primary vessel via a blowdown through the ADS lines. The purpose of the ICSP is to evaluate the applicability of thermal-hydraulic computer codes to unique experiments usually outside of the validation matrix of the code itself. RELAP5-3D 2:4:2 was chosen to model the ICSP. RELAP5-3D is a best-estimate code designed to simulate transient fluid and thermal behavior in light water reactors. Modeling was conducted in RELAP5-3D to identify the strengths and weaknesses of the code in predicting the experimental trends of the IAEA ICSP. This extended to nodalization sensitivity studies, an investigation of built-in models and heat transfer boundary conditions. Besides a qualitative analysis, a quantitative analysis method was also performed. / Graduation date: 2013