International Classification of Diseases the 10th Revision (ICD-10) was implemented October 1, 2015, and there was little knowledge how the transition to ICD-10 would impact the revenue cycle for intraoperative neurophysiological monitoring medical practices in Oklahoma. This correlational quantitative study examined the changes in dependent variables of reimbursements due to the change from ICD-9 to ICD-10 for independent variables of intraoperative neurophysiological monitoring procedure codes. The reimbursements from 2014 were compared to reimbursements from 2016. Prices were adjusted for inflation to 2016 dollar values. Annual reimbursements decreased for all intraoperative neurophysiological monitoring procedures examined except the remote monitoring code. The intraoperative neurophysiological monitoring procedure with the greatest mean annual decreases in reimbursement was the lower somatosensory evoked potentials. The intraoperative neurophysiological monitoring procedures with the least annual reimbursement decreases were transcranial electrical motor potential monitoring and electromyography. The findings of the budget-impact analysis and cost-effectiveness analysis indicated that reimbursement for procedures has steadily decreased from 2014 to 2016, causing a negative effect on practices' revenue cycle management. The findings of this study could benefit intraoperative neurophysiological monitoring companies in Oklahoma by supporting adjustments essential for healthcare leaders to maintain a financially sustainable intraoperative neurophysiological monitoring medical practice.