This thesis focuses on the evolution and framing of xenotransplantation (XTP) policy debate in New Zealand from 1998 to 2011. Its aim is providing a better understanding of both the science-society interface and the importance of issue framing policy debate in understanding of the scientific debate in New Zealand and its relationship with the public. A qualitative study, this thesis draws upon a variety of public science commentary and debate and poses the research question: How did xenotransplantation’s introduction and explanation to the New Zealand public inform its current status as a Restricted Procedure under New Zealand law; and what ethical implications arise from this public policy debate for public participation in bio-medical research in New Zealand?