This thesis is dedicated to an archaeogenetic study of five prehistoric individuals. The sample material comes from central Yakutia, also called Sakha Republic, in the north-eastern part of Russia. The main focus of this study has been the analysis of five mitochondrial genomes, retrieved from osteological material (human bones and teeth), having an estimated age of 6845 BP to 2490 BP. The dates fall within Neolithic, Bronze Age and Early Iron Age. A brief presentation for each individual’s archaeological profile and interpretation of the burial will be provided. While a series of interpretive tests with the mitochondrial DNA material were performed and the results are presented. The neolitization of the north-eastern Eurasia will also be discussed. The correlation between the Neolithic Age, Bronze Age and Early Iron Age populations will be proposed, as well as their connections to modern populations.