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The efficacy of thiosinaminum 1X cream on striaeRamoupi, Koketso 16 October 2012 (has links)
M.Tech. / Striae are linear scars in the dermis which arise from rapid stretching of the skin over weakened connective tissue (de Angelis & Adatto, 2010). Striae occur when collagen production cannot keep pace with a sudden growth of the underlying tissues. Striae have no medical consequences but are frequently distressing to those afflicted. These disfiguring marks are usually caused by excessive stretching of the skin that may occur with pregnancy, adolescent growth spurts, obesity and weightlifting (Kang & Arbor, 1998). Striae usually appear on the abdomen, thighs, buttocks, breasts and extremities. Patients’ quality of life can be enhanced with the effective management of these unsightly marks. Modalities of treatments that exist for the treatment of striae have been advocated with varying success and side effects (Manuskiatti et al., 2010). The aim of this study was to determine the efficacy of the topical application of a homoeopathic preparation Thiosinaminum 1X on the appearance of striae. The research was a double-blind placebo controlled study which took place at the Homoeopathy Health Centre which is located at the University of Johannesburg(Doornfontein campus). Forty female participants aged between eighteen and thirty-five were randomly selected to take place in the study. The study was conducted over a period of twelve weeks. On recruitment, the participants were required to read and sign the information sheet (Appendix A) and consent form (Appendix B) assisted by the researcher. Participants were asked to complete a questionnaire (Appendix C) to determine contributing factors e.g. duration of the stretch marks, the cause of the stretch marks and any disease that may contribute to the formation of stretch marks. A pertinent case and vital signs were taken at the initial consultation to eliminate any pathologies. All potential participants were required to present with stretch marks on the thighs or buttocks present for at least 6 months prior to the study. The stretch marks needed to have had a minimum length of 50mm and a maximum length of a 100mm. The researcher was responsible for choosing the designated area that was treated. The most distinct striae were selected by the researcher according to criteria for treatment. The researcher took photographs of the treatment areas at the commencement of the study and this was repeated at the end of the study (Appendix I). The length of the most prominent stretch mark (according to criteria) below was also measured on the commencement of the study. To physically iv measure the most prominent stretch mark a string and a ruler was utilized. The same ruler and ball of string was used each time to ensure validity of the results. A new piece of string was cut and tied in a knot at the tip and placed on the stretch mark itself to mould to its shape and thereafter it was placed on a ruler to determine the measurements in millimeters. To ensure that the same stretch mark was measured every time, the researcher measured out the distance between the stretch mark and a defined anatomical point for all the participants. The stretch mark was traced using plotting paper. The participants were required to apply the cream twice daily for the duration of the study. Participants were able to rate their satisfaction on a monthly basis by completing a questionnaire. The results of the study indicated that there was no improvement in the length of striae however there was more improvement in satisfaction ratings throughout the study from the experimental group.
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