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The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
provided by the
Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
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Showing 271 to 273 of 273 (0.111 seconds)| 271 |
"Determinantes funcionais e morfológicos de ação de droga sobre os pulmões utilizando um modelo experimental em cobaias sob uso do cloridrato de fluoxetina" / Functional and morphological determinants of drug action on the lungs through an experimental model in guinea pigs under use of fluoxetineMarco Antonio Capelozzi 15 February 2005 (has links)
Muito se tem pesquisado sobre os efeitos adversos dos antidepressivos tricíclicos (p.e. imipramina) sobre o sistema respiratório, embora pouco ou quase nada se encontre com relação a tal aspecto na literatura médica sobre a fluoxetina (Prozac®) um inibidor seletivo da recaptação de serotonina, até porque esta droga começou a ser utilizada somente há cerca de quinze anos. Ambas substâncias (fluoxetina e imipramina, ou seus congêneres) agem basicamente sobre quadros depressivos, fóbicos e obsessivo-compulsivos, obesidade, anorexia, e outras indicações de várias naturezas, indo desde a ansiedade até a sindrome do pânico. Nota-se entretanto, que na maioria dos pacientes com tais quadros (sob tratamento com a fluoxetina ou não), são muito frequentes as queixas de natureza respiratória, como tosse, falta de ar, angústia" no peito etc. Alguns efeitos adversos da fluoxetina e seus derivados são descritos na literatura, embora raros. Entre eles, destaca-se o comprometimento do aparelho respiratório na forma de doença pulmonar intersticial, pneumonia de hipersensibilidade e fosfolipidose. Apresentamos a seguir um projeto de trabalho experimental em cobaias com intuito de verificar a ação da fluoxetina sobre o aparelho respiratório, com relação à mecânica pulmonar, influência sobre o óxido nítrico exalado e resposta histopatológica pulmonar frente a possíveis injúrias, comparados a animais controles sem efeito da droga. Nosso modelo descreve um protocolo em que os animais foram submetidos ao cloridrato de fluoxetina por via oral durante 30 dias consecutivos, sendo ainda submetidos a uma reação de estresse tipo pânico a natação forçada. / Although high-affinity imipramine binding sites have been reported in both rat and human lung, the role of the lungs in the pharmacokinetics of antidepressants like fluoxetine has not received much attention. Imipramine and fluoxetine have their action in depression, obesity, panic and anxiety among other indications. However, accumulation of selective serotonin-reuptake inhibitors- like fluoxetine, in the human lungs has been reported. Besides, it is very frequent to most patients (under fluoxetine treatment or not) present respiratory symptoms and/or signs, just like dyspnea, cough, chest anguish and so on. There also have been some adverse effects of fluoxetine described in the literature, although being few and isolated ones, related to hypersensitivity pneumonitis, phospholipidosis and interstitial lung disease. The purpose of this project is to investigate the fluoxetine action in respiratory tract, more specifically over the pulmonary interstitium, using an experimental model in guinea-pigs. Our project comprehends an experimental model with the animals under treatment of fluoxetine so that we could evaluate the substance effects on the respiratory system, concerning the mechanics and the lung histopathological aspects, compared to the control animals. We created then a protocol where the animals were treated with fluoxetine for 30 consecutive days and submmited to the forced swimmig test, a kind of panic-like reaction.
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Pantomima Alfreda Jarryho / The Alfred Jarry PantomimePlicková, Karolina January 2013 (has links)
The aim of this diploma thesis is to employ a theatrological approach to the work of one of the most original and influential Czech pantomime troupes of all time, entitled Pantomima Alfreda Jarryho (the Alfred Jarry Pantomime, AJP). The company was established in 1966 in Prague by two young mime artists Boris Hybner and Ctibor Turba and existed as late as the political liquidation of the troupe in 1972 that came due to the process of the so-called normalization period in the former Czechoslovakia. The thesis consists of four major parts that are divided into several subsections. The first part deals with the historical contexts of the art of mime, both international and domestic. The AJP troupe represents the second generation of Czech pantomime that refused the style of the so-called modern pantomime expressed in the international context by Marcel Marceau and in the Czech context by Ladislav Fialka at the Theatre Na zábradlí (Theatre on the Balustrade). Since there is no monograph strictly based on this theatre, although it played a major role among the newly established small theatres in the sixties (and had an important influence on the poetics of the AJP troupe), we briefly introduce the poetics of both the pantomime company led by Fialka and the drama company led by the director Jan Grossman,...
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Grassroots Canadian Muslim Identity in the Prairie City of Winnipeg: A Case Study of 2nd and 1.5 Generation Canadian MuslimsHameed, Qamer January 2015 (has links)
What are grassroots “Canadian Muslims” and why not use the descriptor “Muslims in Canada”? This thesis examines the novel concept of locale specific grassroots Canadian Muslim identity of second and 1.5 generation Muslims in the prairie city of Winnipeg, Manitoba. The project focuses on a generation of Muslims that are settled, embedded, and active in a medium sized Canadian metropolis. Locale plays a powerful part in the way people navigate identities, form attachments, find belonging, and negotiate communities and society. In order to explore this unique identity a case study was conducted in Winnipeg. Interviews with 1.5 and second generation Muslims explored the experience of grassroots Canadian Muslim identity. The project does not focus on religious doxy or praxis but rather tries to understand a lived Canadian Muslim identity by exploring discourse and space as well as strategies, social perceptions and expectations. Participant observation, community resources and literature also aid in the understanding of the grassroots Canadian Muslim experience. This study found that the attachments, networks, and experiences in the locale give room for an embedded Canadian Muslim experience and more negotiable identities than most studies on Muslims in Canada describe. These individuals are not foreigners living in Canada. Their worldviews develop out of this particular and embedded grassroots experience. They navigate a new kind of hybrid Canadian Muslim identity that is unique and flexible. This is the Canadian Muslim experience of 2nd and 1.5 generation Winnipeg Muslims.
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