Orientador: Marina Suely Kofes / Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Filosofia e Ciências Humanas / Made available in DSpace on 2018-08-20T16:05:48Z (GMT). No. of bitstreams: 1 Kabengele_DanieladoCarmo_D.pdf: 5740814 bytes, checksum: 1643ec9d7294eadc862eabc2a03cee50 (MD5) Previous issue date: 2012 / Resumo: Este trabalho é uma narrativa histórica em torno da trajetória de Antonio Ferreira Cesarino (1808-1892). O objetivo foi procurar apresentar o itinerário de Cesarino, observando o período histórico e os contextos em que viveu. Movendo-se dentro de uma sociedade racialmente hierarquizada, mas afeita a lógicas raciais contextuais, Cesarino, negro, era classificado sob o designativo "pardo". Numa visão dialética, verificou-se que a classificação de Cesarino na categoria parda se deu devido a uma leitura de sua cor em relação à sua condição social e ações sociais. Além disso, argumento que o designativo pardo, operando como modalidade oposicional, era um sinal diacrítico utilizado para demonstrar a diferença. O expressivo desempenho sócio-profissional e o prestígio que Cesarino alcançou ao longo da vida se fez possível também por força de sa condição social, de suas ações e pela prática de mercês e de troca de mercês. Para este trabalho, as mercês e a troca de mercês foram entendidas como préstimos, favores, dádivas, cordialidades, esforços e toda sorte de princípios e práticas úteis e proveitosas que se conectam com as capacidades de dar, receber e retribuir. O cenário escolhido para a análise é móvel, deslocando-se da Vila do Paracatu do Príncipe, noroeste mineiro, para a Vila de São Carlos, futura cidade de Campinas, interior paulista, entre a primeira década do século XIX e os primeiros anos do XX. A narrativa e a análise da trajetória de Cesarino expõem alguns traços pertinentes de sua biografia, compreendendo, em especial, as relações desse homem com a sociedade em que vivia e as disposições presentes nesse campo / Abstract: The here presented work constitutes a historical narrative constructed around the life trajectory of Antonio Ferreira Cesarino (1808-1892). The aim was to present the itinerary of this man, noting the historical period and the contexts in which he lived. Moving in racially hierarchical society which had logical racial contextual, Cesarino, a black man, was classified as "pardo" (brown). In a dialectical view, I will suggest that an identification as pardo was attributed in intersection with his social conditions well as his particular social action. In parallel, I argue that the designation pardo, operating as oppositional mode, was a diacritical signal used to demonstrate the difference. For Cesarino, reaching the expressive social and professional performance and a high level of prestige was only possible, given specific social conditions, his own actions, as well as the practise and exchange of "mercês". As result of my research, I assume that the practise of mercês or its exchange can be understood as borrowings, donations, favors, efforts, altogether, as the useful and profitable practices that are bound together by the capacities of giving, receiving and returning. In terms of spacial scenary, my work choses a rather flexibel focus for analysis, switching from Vila do Paracatu do Príncipe, in the northeast of Minas Gerais to Vila São Carlos, a place later to become the city of Campinas, a country town of São Paulo state. The discussion is situated between the first decades of the 19th and the first years of the 20th century. Narrative and analysis about the life trajectory of Cesarino brings several pertinent aspects of his biography leading to a deeper understanding of this man?s relationship to the society he lived in and opportunities avaiable in that context / Doutorado / Antropologia Social / Doutor em Antropologia Social

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior / Most of the features are displayed by complex organisms results of multifactorial inheritance, such as skin color in humans. This study aimed to investigate the high school students conceptions about multifactorial inheritance and, based on the information collected, develop educational materials that promote the application of genetic concepts in everyday matters. Participated in this study 48 students from two high school classes, enrolled in two public schools in Santa Maria / RS and São Vicente do Sul / RS. The survey was conducted in three stages called application of pre-test, didactic approach and implementation of the post-test. We develop a game, a didactic model and a hypertext is recommended for high school classes. The game and the teaching model was applied by the researcher and indicate their use for classes that have studied basics of monogenic and multifactorial inheritance. The applied materials were evaluated as motivation and use of genetic concepts. The evaluation by students and teachers indicated that the proposal is challenging and useful for genetic education with good applicability to review concepts. Hypertext was developed in three versions, according to the student's reality, being a material useful for situations where you have little time to teaching content to be a practical and easy handling means. To make it more interesting and interactive activity is recommended to be done beyond reading a discussion so that students and teachers can share ideas on the subject under study. Students from both groups showed an increase in the proportion of correct answers after the application of the didactic sequence, this improvement was most notable for the students in the class had a low rate of correct answers in the pre-test which had not studied the subject multifactorial inheritance ( class 2). / A maioria das características apresentadas pelos organismos complexos são resultados de heranças multifatoriais, como por exemplo, a cor da pele nos seres humanos. Este trabalho teve como objetivo investigar as concepções de alunos do Ensino Médio sobre herança multifatorial e, com base nas informações coletadas, desenvolver materiais didáticos que favoreçam as aplicações de conceitos de genética em assuntos do cotidiano. Participaram deste trabalho 48 alunos de duas turmas de Ensino Médio, matriculados em duas escolas públicas localizadas em Santa Maria/RS e São Vicente do Sul/RS. A pesquisa foi realizada em três etapas denominadas aplicação do pré-teste, abordagem didática e aplicação do pós-teste. Desenvolvemos um jogo, um modelo didático e um hipertexto sendo recomendados para turmas de Ensino Médio. O jogo e o modelo didático foram aplicados pela pesquisadora e indicamos a sua utilização para turmas que já estudaram conceitos básicos de herança monogênica e multifatorial. Os materiais aplicados foram avaliados conforme motivação e utilização de conceitos de genética. A avaliação por alunos e professores indicou que a proposta é desafiadora e útil para o ensino de genética, com boa aplicabilidade para revisar conceitos. O hipertexto foi desenvolvido em três versões, de acordo com a realidade do aluno, sendo um material útil para situações em que se tenha pouco tempo para o ensino do conteúdo por ser um meio prático e de fácil manipulação. Para tornar a atividade mais interessante e interativa recomenda-se que seja feita além da leitura uma discussão para que os alunos e professor possam compartilhar ideias sobre o tema em estudo. Os alunos de ambas as turmas apresentaram aumento na proporção de respostas corretas após a aplicação da sequência didática, essa melhora foi mais notável para os alunos da turma que teve baixo índice de acertos no pré-teste a qual não havia estudado o tema herança multifatorial (turma 2).

This is a step-by-step cosmetology handbook with instructions and techniques employed by professional makeup artists to transform a woman from average to gorgeous.

L’espérance de vie des patients atteints de mélanome à haut risque ne peut être prédite d’une façon<p>fiable en se basant sur les analyses d’histopathologies de la lésion primitive et est souvent ajustée<p>durant la progression de la maladie. Notre étude vise à élargir nos observations initiales au niveau<p>des métastases cutanées et d’évaluer la valeur pronostique de tyrosinase related protein 1 (TYRP1)<p>dans les métastases ganglionnaires des patients atteints de mélanome de stades III et IV. TYRP1 est<p>une enzyme mélanosomale qui partage des similitudes structurelles avec la tyrosinase, l'enzyme clé<p>de la mélanogenèse.<p>L’expression de l'ARNm de TYRP1 a été quantifiée dans 104 métastases ganglionnaires par PCR<p>en temps réel et normalisée par rapport à l’expression de l’ARNm de S100B (marqueur reconnu du<p>mélanome) pour corriger l’expression de TYRP1 suivant la charge tumorale de l’échantillon. Le<p>rapport TYRP1/S100B a été calculé et la médiane a été utilisée en tant que valeur seuil. Ensuite<p>nous avons étudié la relation entre les valeurs de TYRP1/S100B, le suivi clinique et les<p>caractéristiques histopathologiques de la tumeur primitive.<p>Un rapport élevé de l’ARNm TYRP1/S100B corrélait significativement avec une survie sans<p>récidive et une survie globale plus courtes, avec une épaisseur de Breslow plus élevée et avec la<p>présence d'une ulcération au niveau de la tumeur primitive. En outre, une expression élevée de<p>TYRP1/S100B était de meilleure valeur pronostique pour la survie globale que l'épaisseur de<p>Breslow et l'ulcération des primitifs. De plus, cette expression est bien conservée au cours de la<p>progression de la maladie par rapport aux groupes de TYRP1 bas/élevé.<p>Nous avons constaté qu’une expression élevée de TYRP1/S100B dans les métastases de patients<p>atteints de mélanome est associée à un résultat clinique défavorable et une survie courte. Menée sur<p>des patients atteints d'un mélanome à haut risque de récidive, cette première étude a suggéré que<p>l'ARNm de TYRP1 dans les métastases pourrait servir de biomarqueur pour affiner le pronostic<p>initial des patients surtout ceux ayant des lésions primitives de localisation inconnues ou non<p>évaluables et peut permettre une gestion différente des deux groupes de patients. Son expression<p>conservée au cours de la progression de la maladie est en faveur de son utilisation comme cible<p>thérapeutique.<p>En second lieu, en évaluant l’expression de la protéine TYRP1 par immunohistochimie dans les<p>métastases cutanées et ganglionnaires, nous avons observé qu’elle n'était pas détectée dans la moitié <p>7<p>des tissus exprimant bel et bien l'ARNm correspondant et qu’elle, contrairement à l'ARNm, n’était<p>pas associée à la survie.<p>Des données récentes ont indiqué que le 3'-UTR de l’ARNm de TYRP1 contient trois sites de<p>liaison putatifs de miR-155 dont deux présentant un polymorphisme d'un seul nucléotide (SNPs:<p>rs683 et rs910) qui favorisent la dégradation en cas d’hybridation miARN-ARNm parfaite de<p>l’ARNm ou non en cas d’hybridation imparfaite. Nous avons cherché à examiner si miR-155 peut<p>affecter l’expression de l’ARNm et de la protéine TYRP1 en fonction de ces SNPs. Tout d'abord,<p>nous avons transfecté deux lignées de mélanome ayant chacune l’une ou l’autre de l’allèle (au<p>niveau rs683 et rs910) avec différentes concentrations de pré-miR-155 et nous avons évalué<p>l’expression du miR-155 et l’ARNm TYRP1 par PCR en temps réel ainsi que l’expression de la<p>protéine TYRP1 par western blot. Nous avons constaté qu’une surexpression de miR-155 a induit<p>une dégradation importante des ARNm TYRP1 et a perturbé sa traduction en protéine dans la lignée<p>avec le génotype “hybridation parfaite”. Ensuite, nous avons examiné l'expression des ARNm et<p>protéines de TYRP1, le niveau de miR-155 et les SNPs rs683 et rs910 dans 192 échantillons de<p>métastases cutanées et ganglionnaires de mélanome. Nous avons trouvé que le groupe d'échantillons<p>avec le génotype “hybridation parfaite” était significativement associé à un niveau de protéine de<p>TYRP1 plus bas alors qu'aucune différence de niveau d’expression n'a été trouvée pour l’ARNm de<p>TYRP1 ou miR-155 entre les deux groupes de génotype, confirmant que les SNPs au niveau de 3’-<p>UTR de TYRP1 peuvent spécifiquement affecter l'expression de la protéine TYRP1. En outre, nous<p>avons montré que l’ARNm de TYRP1 est inversement corrélé avec l’expression miR-155, mais pas<p>avec la protéine TYRP1 dans le groupe " hybridation parfaite", alors qu'il corrèle positivement avec<p>la protéine mais pas avec miR-155 dans le groupe "hybridation imparfaite" où la protéine corrélait<p>inversement à la survie. Cela montre que les SNPs dans le 3'-UTR de l'ARNm TYRP1 affectent la<p>régulation de l’ARNm par miR-155 et la traduction en protéine. Ces SNPs rendent la régulation de<p>l’ARNm et la protéine de TYRP1 indépendante de miR-155 et confèrent une valeur pronostique à<p>la protéine TYRP1 / Doctorat en Sciences biomédicales et pharmaceutiques / info:eu-repo/semantics/nonPublished

Indiana University-Purdue University Indianapolis (IUPUI) / In the past, the present and the future, Lebanon has been an important link between the East and the West. It was always known as the ‘Switzerland of the East’. Over the years, it was a hotspot for different civilizations that uniquely shaped the genomic backbone of the current Lebanese. It is also a good representation of genetically admixed individuals with diverse phenotype characteristics and unique features. Lebanon, quite like other Middle Eastern populations, lacks sufficient genetic studies that helps to better comprehend the complex genomic composition of different traits and diseases. The lack of good representation of the Middle East and North Africa (MENA) region in global studies has led to ambiguity in discovering special ancestry markers and patterns in the Lebanese genome. Yet, in this study, a thorough investigation into a Lebanese collection shows new patterns that potentially would be helpful in forensic and genealogical applications. The investigation into the autosomal and Y-STRs revealed unique alleles that would be valuable in future forensic investigation analysis. In addition, the assessment of phenotype prediction models to predict eye, hair and skin color showed promising results in terms of prediction performance. Those results encourage the future use of intelligence tools in the regions that in return would aid in serving justice and furthering science research. In fact, ancestry and genetic distance studies confirms the presence of admixture within Lebanon between Europe and North Africa. / 2029-06-01

Stress is a common health problem among students, and individuals with a minority identity might also experience minority stress. Minority stress associated with skin color is a relatively unexplored topic in Sweden; thus this study aims to investigate a possible connection between students' skin color and their minority stress from a jobseeker's perspective. To investigate this, a digital survey consisting of 25 items was carried out. Participants (n=177)  were recruited through convenience sampling and categorized into three groups based on skin color (light, medium light/dark, dark). A one-way ANOVA was carried out to test the study's hypothesis that students with darker skin have a higher degree of minority stress prior to the job search process than students with lighter skin. The result showed a significant difference between the groups(F2,174=34.5, p&lt;.001, 2= .275) and a post-hoc test (Tukey) showed significant differences between each group. The result was consistent with the study's hypothesis and previous research. Furthermore, this study concludes that minority stress can give rise to mental illness. Additionally, the study concludes that Meyer's American framework, which aims to measure minority stress in gay and bisexual individuals, can be applied in a Swedish context with racist stress factors. For further research, a more representative sample would be beneficial, as well as a broadened perspective by examining how schools and workplaces work to counter minority stress, which in turn could prevent mental illness.

The ownership and demand for fitness trackers, smartwatches, and wrist-worn deviceshave been increasing globally. These devices offer various features such as measuringphysical activity, sleep monitoring, and health-related measurements like heart rate andheart rate variability using PhotoPlethysmoGraphy (PPG). However, research indicatesthat PPG measurements are less accurate on darker skin compared to lighter skin due to thehigher presence of melanin, a light-absorbing substance in dark skin.This thesis addresses the impact of melanin on the accuracy of heart rate measurements ondifferent skin colors using four commercial smartwatches, Apple Watch Series 5, FitbitCharge 2, Xiaomi Miband 3, and Sony mSafety. The study involves analyzing the accuracyof these smartwatches on individuals with varying skin colors while controlling forexternal factors. The collected data from the smartwatches are compared to a referencesensor that uses electrocardiography (ECG) measurements with electrodes placed aroundthe chest. Three different tests are conducted wearing the devices, with no movement,while walking, and with circular hand motions.The tests were conducted on twelve participants representing the 6 different skin typescategorized using the Fitzpatrick scale. With the presented results in this thesis, it wasconcluded that the 4 smartwatches' measurement accuracy does not seem to be dependenton specific skin types. Ranked in terms of Mean Absolute Error (MAE), the Apple Watchshowed the lowest value, followed by Xiaomi, Fitbit and the mSafety and that the accuracydid not depend on skin color. / Ägandet och efterfrågan av smartklockor har ökat globalt. Dessa enheter erbjuder olikafunktioner som mäter fysisk aktivitet, övervakning av sömn och hälsorelaterade mätningarsom puls och hjärtfrekvensvariabilitet med hjälp av PhotoPlethysmoGraphy (PPG).Forskning har dock visat att PPG-mätningar är mindre noggranna på mörkare hud jämförtmed ljusare hud på grund av den högre närvaron av substansen melanin, ettljusabsorberande ämne.Syftet med detta arbete är att undersöka påverkan av melanin på noggrannheten i pulsmätningar på olika hudfärger med hjälp av fyra kommersiella smartklockor: Apple WatchSeries 5, Fitbit Charge 2, Xiaomi Miband 3 och mSafety av Sony. Arbetet inkluderar enanalys av dessa smartklockors noggrannhet på personer med de olika hudfärger samtidigtsom externa faktorer som kan påverka noggrannheten kontrolleras. De insamlade data frånsmartklockorna jämförs med en referenssensor, Polar band, som använderelektrokardiografimätningar (ECG) med elektroder. Tre olika tester utförs med enheterna,utan rörelse, medan man går och med cirkulära handrörelser.Testerna utfördes på tolv deltagare som representerar olika hudtyper kategoriserade enligtFitzpatrick-skalan. Utifrån de presenterade resultaten i denna avhandling drogs slutsatsenatt de fyra smartklockornas mätnoggrannhet inte verkar vara beroende av specifikahudtyper. Rankade i termer av Mean Absolute Error (MAE) visade Apple Watch det lägstavärdet, följt av Xiaomi, Fitbit och mSafety.

O objetivo deste trabalho é criar uma metodologia capaz de reconhecer gestos de mãos, a partir de imagens dinâmicas, para interagir com sistemas. Após a captação da imagem, a segmentação ocorre nos pixels pertencentes às mãos que são separados do fundo pela segmentação pela subtração do fundo e filtragem de cor de pele. O algoritmo de reconhecimento é baseado somente em contornos, possibilitando velocidade para se trabalhar em tempo real. A maior área da imagem segmentada é considerada como região da mão. As regiões detectadas são analisadas para determinar a posição e a orientação da mão. A posição e outros atributos das mãos são rastreados quadro a quadro para distinguir um movimento da mão em relação ao fundo e de outros objetos em movimento, e para extrair a informação do movimento para o reconhecimento de gestos. Baseado na posição coletada, movimento e indícios de postura são calculados para reconhecimento um gesto significativo. / The purpose of this paper is to develop a methodology able to recognize hand gestures from dynamic images to interact with systems. After the image capture segmentation takes place where pixels belonging to the hands are separated from the background based on skin-color segmentation and background extraction. The image preprocessing can be applied before the edge detection. The recognition algorithm uses edges only; therefore it is quick enough for real time. The largest blob from the segmented image will be considered as the hand region. The detected regions are analyzed to determine position and orientation of the hand for each frame. The position and other attributes of the hands are tracked per frame to distinguish a movement from the hand in relation to the background and from other objects in movement, and to extract the information of the movement for the recognition of dynamic gestures. Based in the collected position, movement and indications of position are calculated to recognize a significant gesture.

O objetivo deste trabalho é criar uma metodologia capaz de reconhecer gestos de mãos, a partir de imagens dinâmicas, para interagir com sistemas. Após a captação da imagem, a segmentação ocorre nos pixels pertencentes às mãos que são separados do fundo pela segmentação pela subtração do fundo e filtragem de cor de pele. O algoritmo de reconhecimento é baseado somente em contornos, possibilitando velocidade para se trabalhar em tempo real. A maior área da imagem segmentada é considerada como região da mão. As regiões detectadas são analisadas para determinar a posição e a orientação da mão. A posição e outros atributos das mãos são rastreados quadro a quadro para distinguir um movimento da mão em relação ao fundo e de outros objetos em movimento, e para extrair a informação do movimento para o reconhecimento de gestos. Baseado na posição coletada, movimento e indícios de postura são calculados para reconhecimento um gesto significativo. / The purpose of this paper is to develop a methodology able to recognize hand gestures from dynamic images to interact with systems. After the image capture segmentation takes place where pixels belonging to the hands are separated from the background based on skin-color segmentation and background extraction. The image preprocessing can be applied before the edge detection. The recognition algorithm uses edges only; therefore it is quick enough for real time. The largest blob from the segmented image will be considered as the hand region. The detected regions are analyzed to determine position and orientation of the hand for each frame. The position and other attributes of the hands are tracked per frame to distinguish a movement from the hand in relation to the background and from other objects in movement, and to extract the information of the movement for the recognition of dynamic gestures. Based in the collected position, movement and indications of position are calculated to recognize a significant gesture.

With the improvement of multimedia technologies such as broadband-enabled HDTV, video on demand and internet TV, the computer and the TV are merging to become a single device. Moreover the previously cited technologies as well as DVD or Blu-ray can provide menu navigation and interactive content. The growing interest in video conferencing led to the integration of the webcam in different devices such as laptop, cell phones and even the TV set. Our approach is to directly use an embedded webcam to remotely control a TV set using hand gestures. Using specific gestures, a user is able to control the TV. A dedicated interface can then be used to select a TV channel, adjust volume or browse videos from an online streaming server. This approach leads to several challenges. The first is the use of a simple webcam which leads to a vision based system. From the single webcam, we need to recognize the hand and identify its gesture or trajectory. A TV set is usually installed in a living room which implies constraints such as a potentially moving background and luminance change. These issues will be further discussed as well as the methods developed to resolve them. Video browsing is one example of the use of gesture recognition. To illustrate another application, we developed a simple game controlled by hand gestures. The emergence of 3D TVs is allowing the development of 3D video conferencing. Therefore we also consider the use of a stereo camera to recognize hand gesture.