This dissertation describes the theoretic studies of magnetic moment and spinorbit interaction in vacuum (Dirac wavepacket) and solid state systems, such as semiconductors. The semiclassical approach developed here provides a simple and intuitive picture for the origin of spin and spin-orbit coupling. In the Dirac model, the spin magnetic moment is originated from the self-rotating Dirac wavepacket with a correct g-value. The spin-orbit interaction is related to Berry connection (gauge potential) and the model is generalized to solid state systems. The Rashba effect caused by the spin-orbit coupling in a crystal with asymmetric potential in heterostructure quantum well is calculated by semiclassical spindependent scattering. The exact treatment of interface phase accumulation provides a justification of spin-dependent boundary condition at interface derived in previous treatment using Löwdin decomposition. Other spin-orbit coupling related phenomena in solid state system are also discussed in this thesis. / text