The diploma thesis deals with the use of a simulation model for the development of an automatic algorithm for the creation of a routing table and route evaluation in a transport system. It includes a search of modeling and simulation issues and state-space search issues with an analysis of available search methods. The simulation model of the transport system is created in the software Tecnomatix Plant Simulation, where an algorithm for automatic creation of routing tables for routing and evaluation of routes according to static criteria is subsequently developed and tested. The work presents a proposal for the principle of the algorithm for evaluating the routes of the transport system, including dynamic criteria and their optimization.