Global ETD Search

1	Hypothyrodism in rats developmental consequences of varying prenatal doses of thiouracil / Dorcey, Teresa Plucinska. January 1972 (has links) Thesis (M.A.)--University of Wisconsin-Madison, 1972. / eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 42-45). Rats. Hypothyroidism. Thiouracil.
2	Veränderung der Beliebtheit und der Wahrnehmung von Fett im Verlauf eines Gewichtsreduktionsprogramms für Adipöse Einfluss von Fettverzehr, Körpergewicht und PROP-Tasterstatus Kreuter, Petra January 2007 (has links) Zugl.: Giessen, Univ., Diss., 2007
3	Veränderung der Beliebtheit und der Wahrnehmung von Fett im Verlauf eines Gewichtsreduktionsprogramms für Adipöse Einfluss von Fettverzehr, Körpergewicht und PROP-Tasterstatus Kreuter, Petra January 2007 (has links) (PDF) Zugl.: Giessen, Univ., Diss., 2007
4	Veränderung der Beliebtheit und der Wahrnehmung von Fett im Verlauf eines Gewichtsreduktionsprogramms für Adipöse : Einfluss von Fettverzehr, Körpergewicht und PROP-Tasterstatus / Kreuter, Petra. January 2008 (has links) Universiẗat, Diss., 2007--Giessen.
5	Veränderung der Beliebtheit und der Wahrnehmung von Fett im Verlauf eines Gewichtsreduktionsprogramms für Adipöse Einfluss von Fettverzehr, Körpergewicht und PROP-Tasterstatus / Kreuter, Petra. January 2008 (has links) Universiẗat, Diss., 2007--Giessen.
6	Comparison Between PCB Exposure and Hypothyroidism: Behavioral Development in Sprague-Dawley Rats Toth, Cynthia L. 29 July 2009 (has links) No description available. Biology polychlorinated biphenyls hypothyroidism thiouracil, thyroid hormones grooming
7	Inhibitors of SecA as Potential Antimicrobial Agents chaudhary, Arpana S 02 August 2013 (has links) Protein translocation is essential for bacterial survival and the most important translocation mechanism in bacteria is the secretion (Sec) pathway. Thus targeting Sec pathway is a promising strategy for developing novel antibacterial therapeutics. We report the design, syntheses, mechanistic studies and structure-activity relationship studies using HQSAR and 3-D QSAR Topomer CoMFA analyses of 4-oxo-5-cyano thiouracil derivatives. In summary, introduction of polar group such as –N3 and linker groups such as –CH2-O- enhanced the potency as well as logP and logS several fold. We also report the discovery, optimization and structure-activity relationship study of 1,2,4-triazole containing pyrimidines as novel, highly potent antimicrobial agents. A number of inhibitors have been found to inhibit microbial growth at high nanomolar concentrations. SecA inhibitors Sec pathway inhibition Thiouracil 1 2 4-Triazole Novel antibacterial therapeutics Protein translocation inhibition
8	Inhibitors of SecA as Potential Antimicrobial Agents Chaudhary, Arpana S 02 August 2013 (has links) Protein translocation is essential for bacterial survival and the most important translocation mechanism in bacteria is the secretion (Sec) pathway. Thus targeting Sec pathway is a promising strategy for developing novel antibacterial therapeutics. We report the design, syntheses, mechanistic studies and structure-activity relationship studies using HQSAR and 3-D QSAR Topomer CoMFA analyses of 4-oxo-5-cyano thiouracil derivatives. In summary, introduction of polar group such as –N3 and linker groups such as –CH2-O- enhanced the potency as well as logP and logS several fold. We also report the discovery, optimization and structure-activity relationship study of 1,2,4-triazole containing pyrimidines as novel, highly potent antimicrobial agents. A number of inhibitors have been found to inhibit microbial growth at high nanomolar concentrations. SecA inhibitors Sec pathway inhibition Thiouracil 1 2 4-Triazole Novel antibacterial therapeutics Protein translocation inhibition

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