Thesis (Ph. D.)--University of Texas at Austin, 2003. / Vita. Includes bibliographical references. Available also from UMI Company.

published_or_final_version / Orthopaedics and Traumatology / Master / Master of Medical Sciences

Introduction: This study aimed to assess the outcomes and implant survivorship in Chinese patients aged 55 years or younger. Methods: We reviewed our local joint replacement registry on a total of 102 knees from 68 Chinese patients aged 55 years or below at the time of surgery. All patients were operated on from January 2000 to July 2007. The mean followup was 8.3 years (range, 5 ? 12.5 years). We included patients with osteoarthritis (70 knees), rheumatoid arthritis (24 knees), hemophilia (4 knees), psoriatic arthropathy (1 knee), post?traumatic (1 knee) and tuberculosis (2 knees). All implants were cemented. 53 were posterior cruciate ligament (PCL) sacrificing, 47 were posterior stabilized implants and 1 was constrained implant. The preoperative and latest Knee Society Knee Scores, Knee Society Functional Score, knee range of motion and lower limb mechanical alignment on long film measurement were obtained. The postoperative occurrence of radiolucent lines, complications, revision operation and deaths were noted. Each knee was analyzed separately. Results: Mean Knee Society Knee Score improved from 41 (range: 13?79, SD 12.9) to 88 (range: 30?100, SD 13.3)(p <0.0001), while the mean Knee Society Functional Score improved from 41 (range: 0?80, SD 19.2) to 69 (range 0?100, SD 26.5 ) (p<0.0001). 70% achieved a postoperative coronal mechanical axis of within 3 from neutral alignment. Implant survivorship was 97% at 5 years and 85% at 10 years. 11 knees from 9 patients had complications requiring revision surgery. Aseptic loosening occurred in 10 knees of 8 patients. Among those with aseptic loosening, 3 knees from different patients had coexisting osteolysis. Heterotopic ossification occurred in 1 knee. There were no cases of infection. Rheumatoid arthritis patients when compared with osteoarthritis patients had a more valgus preoperative lower limb alignment (p<0.001), a lower mean preoperative KSFS (30 and 45 respectively, p=0.004) and a lower mean postoperative KSFS (53 and 74 respectively, p=0.006). There were no significant differences in mean improvement of KSFS, KSKS, radiological outcomes and implant survival. There were no statistically significant differences in clinical outcomes, radiological outcomes and implant survival between PCL sacrificing and PCL substituting implants. There were no statistically significant differences between the postoperatively neutrally aligned group and the outlying group in terms of clinical outcomes, radiological outcomes and implant survival. Conclusion: Total knee arthroplasty provides good clinical and functional outcomes in young Chinese comparable to those of international standards. Careful patient selection is crucial to avoid complications. / published_or_final_version / Orthopaedics and Traumatology / Master / Master of Medical Sciences

Introduction: This retrospective comparative study was to define the validity and reliability of a translated, culturally adapted Chinese version questionnaire of the New Knee Society Knee Scoring System (NKSS). This study is aim to investigate the validity and reliability of the translated Chinese version of the NKSS and assess its feasibility of measuring the scale on Chinese patients by performing its cross-cultural adaptation for patients after Total Knee Arthroplasty (TKA) in Hong Kong. Methods: A total of 104 knees from 64 Chinese patients performed TKA were included in the study using the translated, culturally adapted Chinese version of the NKSS. All Patients were operated on from October 2010 to May 2013 at Queen Mary Hospital. Patients who participated in this study have been clinically screened and established a set of including criteria. The outpatients were evaluated by completing the five questionnaires containing the NKSS, the Knee Society Clinical Rating System (KSS), Medial Outcomes Study 36+Item Short Form (SF-36), Bristol Knee Score and Oxford Knee Score. Reliability was evaluated using the Split-half reliability, Chronbach's α coefficient and inter-item correlation. To assess validity, all patients filled in the same NKSS questionnaire, and previously validated Chinese version of the SF-36, Bristol Knee Score and Oxford Knee Score. The validity was determined with Content Validity and Contract Validity. Results: The NKSS showed ideal split-half reliability as evidenced by the high correlation coefficient (R>0.7, P<0.05). Chronbach's α coefficient for five major domains demographics, objective knee score, expectations, satisfaction and function was high (α>0.7. P<0.05). Also, the inter-item correlation was also excellent for all domains. For validity, the NKSS was found to have excellent correlation with Bristol Knee Score and Oxford Knee Score, good correlation with KSS and SF 36 Discussion: The NKSS as a validated approach is adapted to the diverse health-related quality of lives and activities of contemporary patients with TKA. Orthopaedics surgeons are allowed to appreciate differences in the priorities of individual patients and the interplay among function, expectation, symptoms, and satisfaction after TKA using this assessment instrument. Conclusion: The results of this study show that the NKSS as a functional status questionnaire has been translated into Chinese without missing any psychometric properties of the original version. This culturally and linguistics adapted Chinese version of the NKSS outcome assessment has satisfactory internal consistency and good validity. It is an adequate and helpful instrument for the evaluation of Chinese speaking patients after TKA in clinical studies. / published_or_final_version / Medical Sciences / Master / Master of Medical Sciences

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Thesis (Ph. D.)--University of Texas at Austin, 2003. / Vita. Includes bibliographical references (leaves 221-235). Also available also in an electronic version.

Thesis (M. Med. Sc.)--University of Hong Kong, 2005.

Thesis (D.PT.)--Sage Colleges, 2010. / "May 2010." "A Capstone project for PTY 768 presented to the faculty of The Department of Physical Therapy Sage Graduate School in partial fulfillment of the requirements for the degree of Doctor of Physical Therapy." Includes bibliographical references.

Thesis (Ph. D.)--University of Oregon, 2006. / Includes bibliographical references (leaves 102-109). Also available online (PDF file) by a subscription to the set or by purchasing the individual file.

Thesis (Ph. D.)--University of Oregon, 2006. / Includes bibliographical references (leaves 102-109).