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The role of APPL1 in the adiponectin signaling : a dissertation /Mao, Xuming. January 2006 (has links)
Dissertation (Ph.D.).--University of Texas Graduate School of Biomedical Sciences at San Antonio, 2006. / Vita. Includes bibliographical references.
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The role of sequestosome 1 (SQSTM1) in Paget's disease of bone a dissertation /Rhodes, Emily C. January 2008 (has links)
Dissertation (Ph.D.) --University of Texas Graduate School of Biomedical Sciences at San Antonio, 2008. / Vita. Includes bibliographical references.
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Investigation of the effect of FE65-ARF6 interaction on neurite outgrowth. / CUHK electronic theses & dissertations collectionJanuary 2013 (has links)
Cheung, Hei Nga. / Thesis (M.Phil.)--Chinese University of Hong Kong, 2013. / Includes bibliographical references (leaves 63-72). / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Abstracts also in Chinese.
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Extent of DNA methylation in biparental hydatidiform moles and functional consequences of NALP7 mutationsDjuric, Ugljesa. January 2006 (has links)
Hydatidiform mole (HM) is an abnormal human pregnancy characterized by cystic degeneration of chorionic villi and absence of embryo. It has been correctly proposed that deregulation of imprinted genes, expressed in a parent-of-origin specific pattern, leads to this pathology due to the fact that biparental and androgenetic HMs are indistinguishable at the phenotypic level. To determine the extent of the abnormal DNA methylation in two biparental moles from a family with a mutation in NALP7, we assessed long interspersed nuclear elements (LINEs), inactive X-linked genes and three tumour suppressor genes and demonstrated their normal levels of methylation. Since the identification of the NALP7 as the causative gene of recurrent HMs, the role of inflammation and immunity has come into light as a possible cause of this disease. Due to the known role of NALP7 in cytokine processing, we addressed the ability of the patients' peripheral blood mononuclear cells (PBMCs) to secrete cytokines in response to stimulation with various antigenic molecules. We found a reduced level of IL-1beta and TNF-alpha secretion by the patients' PBMCs suggesting that abnormal processing of several cytokines may underlie this disease.
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The role of the deleted in breast cancer 1 gene product, DBC-1, in estrogen-independent breast cancer cell survival : a dissertation /Trauernicht, Amy Michelle. January 2007 (has links)
Dissertation (Ph.D.).--University of Texas Graduate School of Biomedical Sciences at San Antonio, 2007. / Vita. Includes bibliographical references.
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Regulation of two WW domain-containing transcriptional co-regulators in mammalian cellsXu, Minghong, January 1900 (has links)
Thesis (Ph.D.). / Written for the Division of Experimental Medicine, Dept. of Medicine. Title from title page of PDF (viewed 2008/03/12). Includes bibliographical references.
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Brain Cav1 Channel/AKAP15 signaling complexes and the role of the distal C-terminus in Cav1 channel regulation in vivo /Marshall, Misty. January 2007 (has links)
Thesis (Ph. D.)--University of Washington, 2007. / Vita. Includes bibliographical references (leaves 85-100).
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Characterization of the functional role of APPL1 phosphorylation in adiponectin signaling a dissertation /Mapes, Rebekka. January 2008 (has links)
Dissertation (Ph.D.).--University of Texas Graduate School of Biomedical Sciences at San Antonio, 2008. / Vita. Includes bibliographical references.
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Extent of DNA methylation in biparental hydatidiform moles and functional consequences of NALP7 mutationsDjuric, Ugljesa January 2006 (has links)
No description available.
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Gene regulation and immune mechanisms in multiple sclerosis experimental models /Marta, Mónica Sofia Calado, January 2007 (has links)
Diss. (sammanfattning) Stockholm : Karolinska institutet, 2007. / Härtill 4 uppsatser.
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