Thesis (doctoral)--University of Copenhagen.

Thesis (doctoral)--University of Copenhagen.

A thesis submitted to the faculty of medicine, University of the Witwatersrand, Johannesburg for the degree of Doctor of Philosophy (Medicine). Johannesburg 1991. / This thesis describes corneal ulceration in the black South African and how the pattern of the disease differs from that seen in white South Africans. Initial comparative surveys of one year each were conducted at St John Eye Hospital and the Johannesburg Hospital. These surveys showed that the main problem area in the black patient was central bacterial corneal ulcers while in the white, central viral ulcers accounted for most of the cases seen. Marginal catarrhal ulceration. in the black was commonly seen but it showed a better response to treatment and a better visual outcome. There was generally a marked male predominance in blacks and this was mainly related to predisposing factors. TIle commonest predisposing factors. in the black. patient were episodes of corneal trauma, climatic droplet keratopathy, corneal scarring, malnutrition and alcohol abuse. Pretreatment with antibiotics was found in nearly half of the patients and this was significantly associated with the absence of significant isolates in 40% of central ulcers. Single Gram-posltlve bacterlal isolates were round in 30% of-central ulcers and single Gram-negative isolates in 15%, While fungal isolates were recovered in 5.5% of central ulcers. Streptococcus pneumoniae was by far the commonest orgllnism. accounting for 42% of SIgnificant bacterial. isolates. This organism and Pseudomonas aeruginos were associated with some of the major complications (deseemetocoeles and perforations). Using fixed treatment regiments the results of treatment in mild and moderate bacterial and fungal keratitis were good, as well as most types of marginal ulcers. Vision was shown to improve significantly in the moderate bacterial infections but not in the severe and complicated bacterial cases, A numerical ranking system for the statistical analysis of visual. acuity is described and the method was found to produce consistent results. In a controlled clinical trial using topical steroids plus antibiotics versus antibiotics alone, no difference in visual outcome could be shown. Complications in the two groups were similar, however, and the steroid did not appear to retard the rate of heating. Recommendations for the incorporation of topical steroid Into a treatment regimen are made. Principles for the management of suppurative keratitis in a developing population are outlined in the conclusions. / AC2017

194 leaves : / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Thesis (M.D.)--University of Adelaide, Dept. of Medicine, 1973

Equine gastric ulcer syndrome (EGUS) is highly prevalent in horses and most commonly found in racing and performance horses. This condition may negatively impact the health and athletic performance of affected horses (Vatistas et al. 1999). Proton pump inhibitors are commonly used to treat EGUS, however, a less expensive method, such as a change of diet, may give similar results. Alfalfa hay may offer some buffering capabilities within the stomach (Nadeau et al. 2000). The objective of this study was to further investigate any possible antiulcerogenic properties of alfalfa hay. Twenty-four Quarter Horse yearlings, 12-16 months of age, were utilized in this study. The 77-d experiment consisted of two 28-d periods separated by a 21-d wash-out period. Horses were endoscopically examined at the beginning and end of each period and blocked into two treatment groups. Treatment 1 included coastal bermuda grass (CB) hay and Treatment 2 included alfalfa hay as the only forage source. Horses were fed in stalls, housed in small dry lots, and subjected to an exercise regimen using a mechanical horse-exerciser. A significant effect of diet, was observed on ulcer score (P< 0.05). CB hay–fed yearlings experienced an increase in ulcer score severity compared to that of alfalfa hay– fed yearlings. Significant healing did not occur during the wash-out period, but horses experienced a significant increase in ulcer score severity (P< 0.05). The outcome of this study suggests that alfalfa hay does have antiulcerogenic capability.

Thesis (M.D.) -- University of Adelaide, Dept. of Medicine, 1973.

No description available.

Thesis--Odense Universitet. / Summary in Danish. Bibliography: p. 147-151.

Thesis--Odense Universitet. / Summary in Danish. Bibliography: p. 147-151.

Thesis (doctoral)--Lund University, 1992. / Added t.p. with thesis statement inserted.