BACKGROUND: Accelerating orthodontic treatment is a priority for clinicians and patients aiming to reduce treatment duration and associated discomforts. This systematic literature review assesses the current evidence regarding the efficacy of surgically assisted acceleration techniques in orthodontics. MATERIALS AND METHODS: In November 2021, an extensive search was conducted across EMBASE, Cochrane, and PubMed databases, yielding a total of 2,022 articles. After application of selection criteria and full text analysis the articles for review, were narrowed down to a total of 26 entries. These studies included Piezocision, Propel, Micro-osteoperforations (MOP), Periodontally Assisted Osteogenic Orthodontics (PAOO), and laser-assisted techniques as interventions. RESULTS: The scrutinized literature revealed that 75% of articles on Piezocision reported a favorable impact on treatment time, whereas MOP was found effective in half of the related articles. The Propel system was deemed beneficial in only 25% of the studies examined. In contrast, both articles evaluating PAOO unanimously found it to be an effective method for accelerating orthodontic tooth movement. CONCLUSION: Our review indicates a significant variance in the success rates of surgically assisted orthodontic acceleration methods, with Piezocision and PAOO displaying the highest efficacy, 1.5-2x faster than control groups. Risk of bias assessment revealed moderate to high risk across our selected studies, with the most common issues including lack of blinding of participants and assessors as well as inconsistent reporting of outcomes.