The doctoral thesis focuses on the Warburg's concept of thought space [Denkraum] and the related concept of artistic creation as an interface between the affections and abstract thinking [Zwischenraum], representing the key concepts of his late work (especially between the years 1920- 1929), culminating in the pictorial atlas Mnemosyne. In this context, the thesis focuses on the motive of ascent as well, and concludes that the pathos formula of ascent plays a crucial historical role in the constitution of modern Denkraum and forms one of the fundamental constitutive parameters of the thought-space, whose own metaphorical perspective is the contemporary aviation. For an adequate reflection of the historical development of this Denkraum, Warburg turns to the physical models of thought and artistic creation, including an attempt to use Einstein's theories of relativity. The key role of the motive of ascent in the constitution of Denkraum subsequently shapes this thought space within the confines of Renaissance humanism.