碩士 / 國立中央大學 / 電機工程研究所 / 100 / This dissertation adopted multi-channel MEG to study the steady-state auditory evoked field (SSAEF) responses in tinnitus patients. In this study, 10 right-handed subjects (5 single-side tinnitus patients), aged from 22 to 50 years (mean age at 33 years) were recruited. MEG experiments were performed in a sound-proof magnetic shielding room. MEG data were recorded at 1000 Hz sampling rate. Auditory stimuli were given to subject’s left ear and right ear separately. Preceding the SSAEF study, pure tone stimulations were given to each subject to ensure the sound loudness was within subject’s acceptable range. The stimulation material of SSAEF was 1000Hz sound modulated by 37 Hz modulation frequency. MEG data were segmented into epochs and decomposed by empirical mode decomposition (EMD) into several intrinsic mode functions (IMF). Task-related IMFs with 37Hz information were identified to reconstruct noise-suppressed SSAEFs. In this study, we found the SSAEFs have the following characteristics in normal subjects: 1. right brain energy is always greater than the left hemisphere, and 2. Greater responses induced by contralateral auditory stimulation. Neverthelss, no similar finding was concluded in tinnitus patients. We guess it is caused by cerebral cortex plasticity, it makes the brain not normal discharge. And We also found disinhibition of SSAEF response in affected side (tinntus ear), it might caused by the some reason.
| Identifer | oai:union.ndltd.org:TW/100NCU05442069 |
| Date | January 2012 |
| Creators | En-Hung Lin, 林恩弘 |
| Contributors | Po-Lei Lee, 李柏磊 |
| Source Sets | National Digital Library of Theses and Dissertations in Taiwan |
| Language | zh-TW |
| Detected Language | English |
| Type | 學位論文 ; thesis |
| Format | 58 |
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